THE EFFECT OF WESTERNIZATION ON THE PSYCHOMOTOR DEVELOPMENT OF AFRICAN (YORUBA) INFANTS DURING THE FIRST YEAR OF LIFE

Abstract Background Canavan disease (CD, MIM # 271900) is a rare and devastating leukodystrophy of early childhood. To identify clinical features that could serve as endpoints for treatment trials, the clinical course of CD was studied retrospectively and prospectively in 23 CD patients. Results were compared with data of CD patients reported in three prior large series. Kaplan Meier survival analysis including log rank test was performed for pooled data of 82 CD patients (study cohort and literature patients). Results Onset of symptoms was between 0 and 6 months. Psychomotor development of patients was limited to abilities that are usually gained within the first year of life. Macrocephaly became apparent between 4 and 18 months of age. Seizure frequency was highest towards the end of the first decade. Ethnic background was more diverse than in studies previously reported. A CD severity score with assessment of 11 symptoms and abilities was developed. Conclusions Early hallmarks of CD are severe psychomotor disability and macrocephaly that develop within the first 18 months of life. While rare in the first year of life, seizures increase in frequency over time in most patients. CD occurs more frequently outside Ashkenazi Jewish communities than previously reported. Concordance of phenotypes between siblings but not patients with identical ASPA mutations suggest the influence of yet unknown modifiers. A CD severity score may allow for assessment of CD disease severity both retrospectively and prospectively.

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In congenital hypothyroidism bone maturation at birth may be a predictive factor of psychomotor development during the first Year of life irrespective of other variables related to treatment

Acta Endocrinologica ◽

10.1530/eje.0.1490001 ◽

2003 ◽

pp. 1-6 ◽

Cited By ~ 42

Author(s):

M Wasniewska ◽

F De Luca ◽

A Cassio ◽

N Oggiaro ◽

P Gianino ◽

...

Keyword(s):

Congenital Hypothyroidism ◽

Psychomotor Development ◽

First Year ◽

X Rays ◽

Bone Maturation ◽

Gestation Age ◽

Group A ◽

One Year ◽

First Year Of Life ◽

Tsh Levels

OBJECTIVE: To evaluate in a cohort of infants with congenital hypothyroidism (CH): (a) the frequency of bone maturation (BM) retardation at birth and (b) whether BM delay at birth may be considered as a tool to make a prognosis of psychomotor status at the age of 1 Year, irrespective of other variables related to treatment. DESIGN: BM at birth, CH severity and developmental quotient (DQ) at the age of 1 Year were retrospectively evaluated in 192 CH infants selected by the following inclusion criteria: (a) gestation age ranging between 38 and 42 weeks; (b) onset of therapy within the first Month of life; (c) initial thyroxine (l-T(4)) dosage ranging from 10 to 12 microg/kg/day; (d) normalization of serum thyrotropin (TSH) levels before the age of 3 Months; (e) Monthly adjustments of l-T(4) dose during the first Year of life with serum TSH levels ranging from 0.5 to 4 mIU/l; (f) no major diseases and/or physical handicaps associated with CH; (g) availability of both thyroid scanning and knee X-rays at the time of treatment initiation; (h) availability of DQ assessment at an average age of 12 Months. METHODS: BM was considered normal if the distal femur bony nucleus diameter exceeded 3 mm (group A) or retarded if either this nucleus was absent (subgroup B1) or its diameter was <3 mm (subgroup B2). DQ was evaluated with the Brunet-Lezine test. RESULTS: In 44.3% of cases BM was either delayed (23.5%) or severely delayed (20.8%). The risk of BM retardation was higher in the patients with athyreosis than in the remaining patients (41/57 vs 44/135, chi(2)=25.13, P<0.005). BM-retarded infants showed a more severe biochemical picture of CH at birth and a lower DQ at the age of one Year compared with the group A patients. If compared with infants of subgroup B2 those of subgroup B1 exhibited significantly lower T(4) levels at birth and a more frequent association with athyreosis (70.0 vs 30.0%; chi(2)=7.49, P<0.01), whereas DQ was superimposable in both subgroups. CONCLUSIONS: (a) BM at birth is delayed in almost half of CH patients and (b) CH severity per se can affect DQ at the age of 1 Year irrespective of other variables related to therapy.

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Basics of physiological carrying babies

Polish Annals of Medicine ◽

10.29089/2020.20.00153 ◽

2021 ◽

Author(s):

Wojciech Kiebzak

Keyword(s):

Web Of Science ◽

Developmental Coordination Disorder ◽

Clinical Work ◽

Psychomotor Development ◽

First Year ◽

Sitting Position ◽

Optimal Conditions ◽

Full Support ◽

First Year Of Life ◽

Coordination Disorder

Introduction: In the first year of life, the spine is very susceptible to various types of overload. During this period, it is extremely important to ensure optimal conditions for the physiological formation of curvature of the spine. Aim: The aim of the work is to present optimal ways of carrying infants, recommended by the authors. Material and methods: Using the keywords: ‘carrying children,’ ‘stacking babies,’ ‘moving babies,’ ‘carrying an infant,’ ‘stacking infants,’ ‘moving infants‘ the following databases were searched: ScienceDirect, Web of Science, PubMed, Scopus and ClinicalKey. Works published after 1990 were searched. The presented text describes the authors’ own experience gained throughout over 30 years of clinical work. Results and discussion: In the first year of life, manner of carrying a child should be adapted to the stage of its psychomotor development. During the first 4 months of life, the baby’s spine needs full support. Between 4 and 8 months of age, it is acceptable to carry the child vertically with relief from the spine. In the period when the child acquires ability to independently assume a sitting position and is able to control positioning of the torso in space, his body weight may rest on the tubers ischiale. Conclusions: (1) Proper way of carrying babies is important in the prevention of developmental coordination disorder in infants in the first year of life. (2) Periodical check-up of carrying position proper for a given stage of a child’s development is recommended.

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Psychomotor Development of the Danzig Quintuplets in Their First Year of Life. A Psychological Evaluation

Acta geneticae medicae et gemellologiae ◽

10.1017/s1120962300024665 ◽

1972 ◽

Vol 22 (S1) ◽

pp. 186-188

Author(s):

M. Bogdanowicz

Keyword(s):

Physical Appearance ◽

Psychological Evaluation ◽

Body Posture ◽

Psychomotor Development ◽

First Year ◽

Intelligence Scale ◽

Rate Of Development ◽

Personality Features ◽

First Year Of Life

A psychological follow-up, based on the Brunet-Lézine Scale, showed a constant progress in the development of the quintuplets, the pace being quite proper from the 5th month on.The children differed from each other: the best pace of psychomotor development was observed in Adam and Ewa, the worst in Piotr.In all children, control of body posture showed the highest rate of development, exceeding the presumed norms. Some delay was observed in speech. The results of the examinations made by the Psyche-Cattell Intelligence Scale agree with those obtained by the Brunet-Lézine Scale.Besides the differences in physical appearance, the children showed differences in personality features.

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The importance of physical treatment in children underwent craniosynostosis surgery in the first year of life

Vojnosanitetski pregled ◽

10.2298/vsp171222021p ◽

2020 ◽

Vol 77 (3) ◽

pp. 324-329

Author(s):

Danijela Pavicevic ◽

Jelena Milosevic ◽

Ivana Petrovic-Markovic ◽

Zoran Milenkovic ◽

Katarina Parezanovic-Ilic

Keyword(s):

Postoperative Period ◽

Motor Development ◽

Surgical Intervention ◽

Psychomotor Development ◽

Favorable Effect ◽

First Year ◽

Moderate Degree ◽

Physical Treatment ◽

And Gender ◽

First Year Of Life

Background/Aim. Craniosynostosis is a condition that occurs intrauterine or develops in the infant period, and represents premature fusion of cranial sutures. This fusion of sutures limits the normal cranium development and leads to disorder in the phase of rapid growth and development of the brain. Creation of craniosynostoses is associated with an increased incidence of developmental delay during the breastfeeding period. Craniosynostoses are treated by surgery. The role of a physiatrist is to postoperatively assess psychomotor development and implement habilitation treatment. The aim of this study was to determine distribution of the type of craniosynostoses according to the age and gender of patients, effectiveness of habilitation treatment and to estimate the somatosensory evoked potential in the preoperative and postoperative period in children who underwent craniosynostosis surgery in the first year of life. Methods. The study was designed as a retrospective research. The data were collected from medical records of 51 children with craniosynostoses and delay in psychomotor development who underwent surgical intervention. The children included in this study, during follow-up, were involved in the habilitation treatment. Results. An early diagnosis and surgical intervention had a favorable effect on the development of motor function in children with craniosynostoses. The importance of stimulation treatment in the postoperative period was also proved for achievement of an adequate degree of motor development in children in relation to age. The results of our study confirmed the results obtained in previously published studies that the children who did not undergo surgery and start with the habilitation treatment immediately after it, had delay in psychomotor development of moderate degree. Conclusion. Habilitation treatment significantly reduced the deviations in psychomotor development of children with craniosynostoses if it started immediately after the surgical procedure.

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PRENATAL EXPOSURE TO MERCURY AND COGNITIVE AND PSYCHOMOTOR DEVELOPMENT AT FIRST YEAR OF LIFE

ISEE Conference Abstracts ◽

10.1289/isee.2011.01742 ◽

2011 ◽

Vol 2011 (1) ◽

Author(s):

Sabrina Llop ◽

Mario Murcia ◽

Mònica Guxens ◽

Aitana Lertxundi ◽

Jesús Ibarluzea ◽

...

Keyword(s):

Prenatal Exposure ◽

Psychomotor Development ◽

First Year ◽

First Year Of Life

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Influence of breastfeeding and iron status on mental and psychomotor development during the first year of life.

Infant Behavior and Development ◽

10.1016/j.infbeh.2017.05.009 ◽

2018 ◽

Vol 50 ◽

pp. 300-310 ◽

Cited By ~ 5

Author(s):

Cristina Jardí ◽

Carmen Hernández-Martínez ◽

Josefa Canals ◽

Victoria Arija ◽

Cristina Bedmar ◽

...

Keyword(s):

Iron Status ◽

Psychomotor Development ◽

First Year ◽

First Year Of Life

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Change in movement patterns asymmetry in infants with central coordination disorder in continuous studies

Biomedical Human Kinetics ◽

10.1515/bhk-2015-0023 ◽

2015 ◽

Vol 7 (1) ◽

Cited By ~ 1

Author(s):

Katarzyna Urban ◽

Zofia Ignasiak ◽

Krzysztof Wronecki ◽

Anna Skrzek

Keyword(s):

Movement Patterns ◽

Psychomotor Development ◽

Control Group ◽

First Year ◽

Group I ◽

Growth Phenomenon ◽

Central Coordination ◽

Group Ii ◽

First Year Of Life ◽

Coordination Disorder

SummaryStudy aim: the aim of the study was to observe the dynamics of changes in postural symmetry in infants during the first year of life, undergoing a therapy using the NDT-Bobath method.Material and methods: the study included a group of 60 term infants diagnosed with central coordination disorder. The course of psychomotor development in the children was compared with a control group of peers aged 3 and 12 months. Group I (study group) consisted of 40 infants who had been subjected to treatment using the NDT-Bobath method. Group II (control group) consisted of 20 infants who, by the decision of the parents, did not undergo the therapy. In group I, four studies were carried out at an interval of every 3 months ± 1 week. In group II, studies were carried out during the 3rd and 12th month.Results: symmetry in body position patterns and movement patterns were analysed. Three levels of a child’s body were subject to the assessment of symmetry. In each study disparities in movement patterns of the left and right side were assessed. Individual features were expressed using scores, according to the principle of the higher the score, the more intense asymmetry.Conclusions: 1. The observed changes in body postural asymmetry in infants during the first year of life are more favourable in the group of children undergoing rehabilitation. 2. The catch-up growth phenomenon among the infants from the control group proceeds more slowly and reaches beyond a child’s first year of life. This indicates the need to include appropriate methods of therapy.

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ORO-Dental Manifestations in West Syndrome

Current Topics in Medicinal Chemistry ◽

10.2174/1568026619666191114122732 ◽

2020 ◽

Vol 19 (31) ◽

pp. 2824-2828 ◽

Cited By ~ 2

Author(s):

Fedora della Vella ◽

Maria Contaldo ◽

Renato Fucile ◽

Francesco Panza ◽

Vittorio Dibello ◽

...

Keyword(s):

Dental Treatment ◽

Epileptic Encephalopathy ◽

West Syndrome ◽

Psychomotor Development ◽

First Year ◽

Dental Eruption ◽

Gingival Enlargement ◽

Development Delay ◽

Oral Abnormalities ◽

First Year Of Life

Background: West Syndrome is a rare epileptic encephalopathy involving infantile spasms, altered electroencephalographic pattern with hypsarrhythmia, and psychomotor development delay. It arises in paediatric patients, generally within the first year of life, in symptomatic or idiopathic form depending on the presence of hereditary features or not. Case report: In this report it is described the case of a West syndrome patient affected by multiple caries, gingival enlargement, dental eruption abnormalities, high-arched palate and MIH, treated at the dental clinic of University of Bari “Aldo Moro”. Discussion: West patients present with multiple oral abnormalities, including altered eruption timing, teeth agenesis, teeth shape and position abnormalities, plaque and calculus accumulation, malocclusions and bad oral habits (mouth breathing, nails biting). Conclusion:: West Syndrome patients’ oral hygiene is generally bad due to their motor difficulty and to their low compliance towards dentists, which entails general anaesthesia to perform dental treatment. West Syndrome pharmacological treatment is usually based on antiepileptic drugs and/or ACTH. These medications are well known for their ability to induce gingival enlargement, increasing the possibility of plaque accumulation and gingivitis development.

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