scholarly journals Chronic Low Dose Cyclophosphamide Treatment of Adult Male Rats: Effect on Fertility, Pregnancy Outcome and Progeny1

1986 ◽  
Vol 34 (2) ◽  
pp. 275-283 ◽  
Author(s):  
Jacquetta M. Trasler ◽  
Barbara F. Hales ◽  
Bernard Robaire
Keyword(s):  
Pregnancy Outcome ◽  
Adult Male ◽  
Low Dose ◽  
Male Rats ◽  
Cyclophosphamide Treatment

scholarly journals Low-dose nicotine self-administration is reduced in adult male rats naïve to high doses of nicotine: Implications for nicotine product standards.

2014 ◽  
Vol 22 (5) ◽  
pp. 453-459 ◽  
Author(s):  
Tracy T. Smith ◽  
Rachel L. Schassburger ◽  
Deanne M. Buffalari ◽  
Alan F. Sved ◽  
Eric C. Donny
Keyword(s):  
Adult Male ◽  
Low Dose ◽  
Male Rats ◽  
Self Administration ◽  
Product Standards ◽  
High Doses

scholarly journals Low-Dose Effects of Ammonium Perchlorate on the Hypothalamic-Pituitary-Thyroid Axis of Adult Male Rats Pretreated with PCB126

2007 ◽  
Vol 97 (2) ◽  
pp. 308-317 ◽  
Author(s):  
Eva D. McLanahan ◽  
Jerry L. Campbell ◽  
Duncan C. Ferguson ◽  
Barry Harmon ◽  
Joan M. Hedge ◽  
...  
Keyword(s):  
Ammonium Perchlorate ◽  
Adult Male ◽  
Low Dose ◽  
Male Rats ◽  
Dose Effects ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
Low Dose Effects

The renal effects of a single and low dose of titanium dioxide nanoparticles in adult male rats

2014 ◽  
Vol 229 ◽  
pp. S190
Author(s):  
Carlos Enrique Escarcega-Gonzalez ◽  
Maria Luisa Rodriguez-Vazquez ◽  
Fernando Jaramillo-Juarez ◽  
Eduardo De La Cerda-Gonzalez ◽  
Haydee Martinez Ruvalcaba
Keyword(s):  
Titanium Dioxide ◽  
Adult Male ◽  
Low Dose ◽  
Titanium Dioxide Nanoparticles ◽  
Male Rats ◽  
Renal Effects

Low dose 4-MBC effect on neuroendocrine regulation of reproductive axis in adult male rats

2008 ◽  
Vol 26 (2) ◽  
pp. 222-224 ◽  
Author(s):  
Maria E. Carou ◽  
Osvaldo J. Ponzo ◽  
Romina P. Cardozo Gutierrez ◽  
Berta Szwarcfarb ◽  
Maria L. Deguiz ◽  
...  
Keyword(s):  
Adult Male ◽  
Low Dose ◽  
Male Rats ◽  
Neuroendocrine Regulation ◽  
Reproductive Axis

The Ginkgo biloba extract (GbE) protects the kidney from damage produced by a single and low dose of carbon tetrachloride in adult male rats

2017 ◽  
Vol 69 (7) ◽  
pp. 430-434 ◽  
Author(s):  
R.M. Chávez-Morales ◽  
F. Jaramillo-Juárez ◽  
M.L. Rodríguez-Vázquez ◽  
M.C. Martínez-Saldaña ◽  
F.A. Posadas del Río ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Adult Male ◽  
Ginkgo Biloba ◽  
Low Dose ◽  
Ginkgo Biloba Extract ◽  
Male Rats

scholarly journals Histological Changes of Stomach and Intestine Induced by Energy Drink (Tiger) in Adult Male Rats

2021 ◽  
Vol 9 (A) ◽  
pp. 735-740
Author(s):  
Maha Al Sammak ◽  
Ahmed Hisham Qassim ◽  
Omer R. Hamdi
Keyword(s):  
Small Intestine ◽  
Goblet Cell ◽  
Adult Male ◽  
Low Dose ◽  
Energy Drinks ◽  
Energy Drink ◽  
Male Rats ◽  
Standard Diet ◽  
Cell Hyperplasia ◽  
Intestinal Villi

BACKGROUND: Nowadays energy drinks are markedly consumed by young people all over the world but till now there were only few literatures that describe their effect on the stomach and small intestine. AIM: The aim of the current study is to highlight the histopathological changes encountered in the stomach and small intestine that are induced by energy drinks. MATERIALS AND METHODS: Thirty adult male albino rats were divided into three groups: a control group given only standard diet and distilled water, a group given a low dose of Tiger energy drink (1 ml/100 mg/rat/day), and a group given a high dose of Tiger energy drink (2 ml/100 mg/rat/day). These drinks were given orally via gastric tube for 1 month duration. RESULTS: Histological assessment of different sections of the stomach and small intestine has revealed parietal cell hyperplasia with congestion of gastric mucosal blood vessels, moreover partial loss of intestinal villi with goblet cell hyperplasia was observed in group treated with low dose of Tiger. Increasing the dose of this drink resulted in mononuclear cell infiltration associated with goblet cell metaplasia which could be an early marker for gastric cancer, furthermore complete loss of intestinal villi and degenerative changes of epithelial cells were seen in intestinal sections. These pathological changes seem to be dose related. CONCLUSION: There is a high risk on the rat’s stomach and small intestine in chronic consumers of energy drinks particularly when taken with no limits. Further work is recommended to delineate the exact mechanism of the pathological findings induced by energy drinks.

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