scholarly journals NON PARENCHYMAL WNTS REGULATE BETA‐CATENIN SIGNALING IN MURINE LIVER ZONATION AND REGENERATION

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Morgan Preziosi ◽  
Hirohisa Okabe ◽  
Minakshi Poddar ◽  
Sucha Singh ◽  
Satdarshan Monga
Keyword(s):  
Beta Catenin ◽  
Liver Zonation ◽  
Murine Liver

scholarly journals Beta-catenin signaling in murine liver zonation and regeneration: A Wnt-Wnt situation!

Hepatology ◽  
2014 ◽  
Vol 60 (3) ◽  
pp. 964-976 ◽  
Author(s):  
Jing Yang ◽  
Laura E. Mowry ◽  
Kari Nichole Nejak-Bowen ◽  
Hirohisa Okabe ◽  
Cassandra R. Diegel ◽  
...  
Keyword(s):  
Beta Catenin ◽  
Liver Zonation ◽  
Murine Liver

scholarly journals Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Ruihua Ma ◽  
Angelica S Martínez-Ramírez ◽  
Thomas L Borders ◽  
Fanding Gao ◽  
Beatriz Sosa-Pineda
Keyword(s):  
Spatial Distribution ◽  
Transgenic Mouse Model ◽  
Acute Injury ◽  
Adult Liver ◽  
Metabolic Functions ◽  
Liver Zonation ◽  
Metabolic Zonation ◽  
Wnt Ligands ◽  
Murine Liver ◽  
Zonation Patterns

The distribution of complementary metabolic functions in hepatocytes along a portocentral axis is called liver zonation. Endothelial secreted Wnt ligands maintain metabolic zonation in the adult murine liver but whether those ligands are necessary to initiate zonation in the immature liver has been only partially explored. Also, numerous non-metabolic proteins display zonated expression in the adult liver but it is not entirely clear if their localization requires endothelial Wnts. Here we used a novel transgenic mouse model to compare the spatial distribution of zonated non-metabolic proteins with that of typical zonated metabolic enzymes during liver maturation and after acute injury induced by carbon tetrachloride (CCl4). We also investigated how preventing Wnt ligand secretion from endothelial cells affects zonation patterns under homeostasis and after acute injury. Our study demonstrates that metabolic and non-metabolic zonation are established non-synchronously during maturation and regeneration and require multiple endothelial Wnt sources.

scholarly journals Endothelial Wnts regulate β‐catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt–Wnt situation

2018 ◽  
Vol 2 (7) ◽  
pp. 845-860 ◽  
Author(s):  
Morgan Preziosi ◽  
Hirohisa Okabe ◽  
Minakshi Poddar ◽  
Sucha Singh ◽  
Satdarshan P. Monga
Keyword(s):  
Liver Zonation ◽  
Murine Liver

1046 miR-34a & beta-CATENIN SIGNALING IN MOUSE LIVER: A COMPLEX NETWORK REGULATING LIVER ZONATION, METABOLISM AND CANCER

2013 ◽  
Vol 58 ◽  
pp. S429-S430
Author(s):  
A. Gougelet ◽  
L. Bachelot ◽  
C. Perret ◽  
S. Colnot
Keyword(s):  
Complex Network ◽  
Mouse Liver ◽  
Beta Catenin ◽  
Liver Zonation

scholarly journals Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells

2018 ◽  
Vol 2 (12) ◽  
pp. 1583-1600 ◽  
Author(s):  
Nirmala Mavila ◽  
Yuanyuan Tang ◽  
Joshua Berlind ◽  
Komal Ramani ◽  
Jiaohong Wang ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Human Liver ◽  
Negative Regulator ◽  
Beta Catenin ◽  
Liver Cancer Cells ◽  
Human Liver Cancer ◽  
Murine Liver ◽  
Human Liver Cancer Cells ◽  
Prohibitin 1

733: The Prognostic Value of E-Cadherin, Alpha-, and Beta-Catenin in Invasive Bladder Cancer Patients: Long Term Follow-Up Study

2004 ◽  
Vol 171 (4S) ◽  
pp. 194-195
Author(s):  
Kyoichi Tomita ◽  
Haruki Kume ◽  
Keishi Kashibuchi ◽  
Satoru Muto ◽  
Shigeo Horie ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Prognostic Value ◽  
Invasive Bladder Cancer ◽  
Beta Catenin ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
E Cadherin

Blockierung des Notch- und Wnt-Beta-Catenin Signalwegs durch GSI IX in CD44+ Tumorstammzellen des Magenkarzinoms

2015 ◽  
Vol 53 (08) ◽  
Author(s):  
S Barat ◽  
X Chen ◽  
C Bui ◽  
P Bozko ◽  
N Malek ◽  
...  
Keyword(s):  
Beta Catenin

Efficiency of si-RNA-mediated knock-down of beta-catenin in primary cultured rat Schwann cells

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
B Gess ◽  
H Halfter ◽  
P Young
Keyword(s):  
Schwann Cells ◽  
Beta Catenin ◽  
Knock Down ◽  
Si Rna

A novel approach to investigate SIRS derived heart failure using a murine liver transplantation model

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
LO Conzelmann ◽  
N Kayhan ◽  
NA Stumpf ◽  
U Gaffga ◽  
AA Peivandi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Liver Transplantation ◽  
Novel Approach ◽  
Murine Liver ◽  
Transplantation Model
Sign in / Sign up

Export Citation Format

Share Document