High prevalence of low serum 25‐OH vitamin D concentrations in women of child‐bearing age in Jordan during summer

Introduction: Indian population has a paradoxically high prevalence of vitamin D deficiency. Maternal vitamin D levels are related to outcomes of pregnancy for mother and foetus. To understand the need for screening and appropriate management decisions, data is needed from various regions of India to explore the magnitude of the problem. Aim: To evaluate the vitamin D levels in pregnant mothers and their newborns at a hospital catering to the affluent population in Mumbai. Materials and Methods: A cross-sectional study was conducted from August to December 2012. A 100 women of Indian origin, between 20-45 years of age and their newborns who were delivered at the Lilavati Hospital and Research Centre in Mumbai were included. Determination of 25 hydroxy (OH) vitamin D, serum calcium, albumin concentration was done in mothers just before delivery and newborns venous cord blood at the time of delivery. Pearson’s correlation test was used for determining relation between maternal and newborns vitamin D levels and Chi-square test for association of maternal vitamin D levels with their sun exposure and newborns birth weight. Results: The distribution of serum 25 (OH) vitamin D status in mothers was 75 deficient (75%), 13 insufficient (13%) and 12 sufficient (12%). Mean serum 25 (OH) vitamin D in mothers was 15.09 ng/mL. The distribution of serum 25 (OH) vitamin D levels in newborns were 78 deficient (78%), 13 insufficient (13%) and 9 sufficient (9%). Mean serum 25 (OH) vitamin D in neonates was 13.82 ng/mL. There was strong correlation between maternal and newborns serum 25 (OH) vitamin D levels with a Pearson correlation coefficient value of 0.94 and the p-value of <0.001. Conclusion: There was a high prevalence of vitamin D deficiency in pregnant mothers associated with hypovitaminosis D in newborns in this hospital-based study catering to affluent population from Mumbai.

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Is low serum 25(OH) vitamin D a risk factor for childhood pneumonias?

Dicle Medical Journal / Dicle Tip Dergisi ◽

10.5798/diclemedj.0921.2012.04.0195 ◽

2012 ◽

Vol 39 (4) ◽

pp. 531-535 ◽

Cited By ~ 3

Author(s):

Tuba Ünal

Keyword(s):

Vitamin D ◽

Risk Factor ◽

25 Oh Vitamin D ◽

Low Serum

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Vitamin D status in 3-6-year-old children of Mananthavady ICDS block in Wayanad, Kerala, India

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20182013 ◽

2018 ◽

Vol 5 (4) ◽

pp. 1226

Author(s):

Arif Mohamed Khan ◽

T. G. Sindhu ◽

M. Vijayakumar

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Cross Sectional Study ◽

Tribal Community ◽

Cross Sectional ◽

Vitamin D Levels ◽

Significant Difference ◽

High Prevalence ◽

25 Oh Vitamin D ◽

Kerala State

Background: Despite plenty of sunlight, vitamin D deficiency has been reported in both urban and rural population in India. This study was conducted to estimate the prevalence of Vitamin D deficiency in children between 3-6 years of age group belonging to Mananthavady ICDS block of Wayanad and to identify the sociodemographic variables affecting its level.Methods: This descriptive cross-sectional study was conducted from December 2014 to June 2015. 140 children were selected from 20 Anganawadis in Mananthavady ICDS block in Wayanad district of Kerala state by random methods. After taking relevant history and conducting detailed clinical examinations, blood samples were taken to assess 25(OH) Vitamin D, calcium, phosphorous and alkaline phosphatase levels. Statistical analysis was done using PASW software. Calculations of means were done using descriptive statistics and comparative analysis was done using independent T test.Results: Out of the 140 children 51 belonged to tribal community. The mean 25(OH) Vitamin D level was 22.7ng/ml. 47.1% of the population had deficient, 35% insufficient and 17.9% adequate Vitamin D levels. There was no statistically significant difference in Vitamin D levels between children of tribal and non-tribal community. There was significant increase in Vitamin D levels during summer when compared to that of winter and autumn seasons.Conclusions: There is a high prevalence of vitamin D deficiency among the rural children of 3-6-year age of Mananthavadi ICDS block. The Vitamin D levels were almost equal between the tribal and non-tribal children. Vitamin D levels are significantly higher during summer when compared to other seasons.

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Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D?: Table 1

Annals of the Rheumatic Diseases ◽

10.1136/ard.2009.120329 ◽

2010 ◽

Vol 69 (6) ◽

pp. 1155-1157 ◽

Cited By ~ 187

Author(s):

H Amital ◽

Z Szekanecz ◽

G Szücs ◽

K Dankó ◽

E Nagy ◽

...

Keyword(s):

Vitamin D ◽

Disease Activity ◽

Lupus Erythematosus ◽

Serum Vitamin ◽

Serum Concentrations ◽

Systemic Lupus ◽

Serum Vitamin D ◽

Z Scores ◽

25 Oh Vitamin D ◽

Low Serum

BackgroundLow serum vitamin D concentrations have been reported in several autoimmune disorders.ObjectiveTo assess whether low serum vitamin D concentrations are related to disease activity of patients with systemic lupus erythematosus (SLE).Methods378 patients from several European and Israeli cohorts were pooled and their disease activity was measured by two different methods: 278 patients had SLE disease activity-2000 (SLEDAI-2K) scores and 100 patients had European Consensus Lupus Activity Measurement (ECLAM) scores. In order to combine the two systems the scores were converted into standardised values (z-scores), enabling univariate summary statistics for the two variables (SLEDAI-2K and ECLAM). The commercial kit, LIAISON 25-OH vitamin D assay (310900-Diasorin) was used to measure serum concentration of 25-OH vitamin D in 378 patients with SLE.ResultsA significant negative correlation was demonstrated between the serum concentration of vitamin D and the standardised values (z-scores) of disease activity scores as measured by the SLEDAI-2K and ECLAM scales (Pearson's correlation coefficient r=−0.12, p=0.018).ConclusionsIn a cohort of patients with SLE originating from Israel and Europe vitamin D serum concentrations were found to be inversely related to disease activity.

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Serum 25-OH Vitamin D Level in Psoriatic Patients and Comparison With Control Subjects

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475415622207 ◽

2015 ◽

Vol 20 (3) ◽

pp. 207-210 ◽

Cited By ~ 6

Author(s):

Masoud Maleki ◽

Yalda Nahidi ◽

Sahar Azizahari ◽

Naser Tayyebi Meibodi ◽

Ali Hadianfar

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Serum Vitamin ◽

Enzyme Linked Immunosorbent Assay ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

High Prevalence ◽

The Difference ◽

25 Oh Vitamin D

Background: Vitamin D has been shown to have immunomodulatory effects, and previous studies have proposed a role of vitamin D deficiency in multiple autoimmune diseases, including psoriasis. Objectives: The aim of this study was to investigate serum vitamin D levels in psoriatic patients and compare them with levels in controls. Methods: This study was carried out in 50 psoriasis patients. Serum vitamin D was measured by enzyme-linked immunosorbent assay. Results: The mean serum vitamin D levels in psoriatic patients and controls were 14.92 ± 6.31 and 12.52 ± 4.54 ng/mL, respectively. The difference was not statistically significant ( P = .06). The prevalence of vitamin D deficiency (<20 ng/mL) was 84.0% in psoriatic patients and 93.0% in controls ( P = .21). Conclusions: Most of the patients with psoriasis had vitamin D deficiency, which may have contributed to the evolution of their psoriasis. However, considering the high prevalence of vitamin D deficiency in Iran, no difference was noted between the psoriatic patients and the controls.

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