scholarly journals Vascular endothelial cell protein expression of adiponectin is related with vascular endothelial function in healthy older adults

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Jeung‐Ki Yoo ◽  
Moon‐Hyon Hwang ◽  
Han‐Kyul Kim ◽  
Meredith J. Luttrell ◽  
Thomas H. Meade ◽  
...  
Keyword(s):  
Older Adults ◽  
Endothelial Cell ◽  
Endothelial Function ◽  
Protein Expression ◽  
Vascular Endothelial Cell ◽  
Cell Protein ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Healthy Older Adults

scholarly journals Age‐related impaired endothelium‐dependent dilation is associated with increased vascular endothelial cell protein expression of NF‐kB in humans

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Iratxe Eskurza ◽  
Anthony J Donato ◽  
Zachary D Kahn ◽  
Annemarie E Silver ◽  
Douglas R Seals
Keyword(s):  
Endothelial Cell ◽  
Protein Expression ◽  
Vascular Endothelial Cell ◽  
Cell Protein ◽  
Vascular Endothelial ◽  
Age Related

scholarly journals The Efficacy of Stretching Exercises on Arterial Stiffness in Middle-Aged and Older Adults: A Meta-Analysis of Randomized and Non-Randomized Controlled Trials

2020 ◽  
Vol 17 (16) ◽  
pp. 5643 ◽  
Author(s):  
Michitaka Kato ◽  
Fumi Nihei Green ◽  
Kazuki Hotta ◽  
Toshiya Tsukamoto ◽  
Yasunari Kurita ◽  
...  
Keyword(s):  
Older Adults ◽  
Arterial Stiffness ◽  
Endothelial Function ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Middle Aged ◽  
Randomized Controlled ◽  
Stretching Exercises

Background: Aerobic exercise is known to reduce arterial stiffness; however, high-intensity resistance exercise is associated with increased arterial stiffness. Stretching exercises are another exercise modality, and their effect on arterial stiffness remains unclear. The purpose of this study was to determine whether stretching exercises reduce arterial stiffness in middle-aged and older adults, performing the first meta-analysis of currently available studies. Methods: We searched the literature for randomized controlled trials (RCTs) and non-RCTs published up to January 2020 describing middle-aged and older adults who participated in a stretching intervention vs. controls without exercise training. The primary and secondary outcomes were changes in arterial stiffness and vascular endothelial function and hemodynamic status. Pooled mean differences (MDs) and standard MDs (SMDs) with 95% confidence intervals (CIs) between the intervention and control groups were calculated using a random effects model. Results: We identified 69 trials and, after an assessment of relevance, eight trials, including a combined total of 213 subjects, were analyzed. Muscle stretching exercises were shown to significantly reduce arterial stiffness and improve vascular endothelial function (SMD: −1.00, 95% CI: −1.57 to −0.44, p = 0.0004; SMD: 1.15, 95% CI: 0.26 to 2.03, p = 0.01, respectively). Resting heart rate (HR) and diastolic blood pressure (DBP) decreased significantly after stretching exercise intervention (MD: −0.95 beats/min, 95% CI: −1.67 to −0.23 beats/min, p = 0.009; MD: −2.72 mm Hg, 95% CI: −4.01 to −1.43 mm Hg, p < 0.0001, respectively) Conclusions: Our analyses suggest that stretching exercises reduce arterial stiffness, HR, and DBP, and improve vascular endothelial function in middle-aged and older adults.

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