Dietary Vitamin E Deficiency as a Modifier of the Associations of Respiratory Outcomes With Air Pollution in Adolescents

Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S249
Author(s):  
J Burns ◽  
D Dockery ◽  
L Neas ◽  
J Schwartz ◽  
B Coull ◽  
...  
Keyword(s):  
Air Pollution ◽  
Vitamin E ◽  
Dietary Vitamin ◽  
Vitamin E Deficiency ◽  
Respiratory Outcomes

scholarly journals Increased anxiety-like behavior is an early symptom of vitamin E deficiency that is suppressed by adrenalectomy in rats

2020 ◽  
pp. 1-27
Author(s):  
Yuki Terada ◽  
Hiroya Ohashi ◽  
Yuki Otani ◽  
Kanako Tokunaga ◽  
Asako Takenaka
Keyword(s):  
Vitamin E ◽  
Social Isolation ◽  
Control Diet ◽  
Underlying Mechanism ◽  
Plasma Corticosterone ◽  
Physical Symptoms ◽  
Dietary Vitamin ◽  
Vitamin E Deficiency ◽  
Adrenal Hormones ◽  
Adrenal Hormone

Abstract We previously reported that dietary vitamin E deficiency increased anxiety-like behavior in rats exposed to social isolation. Here, we performed a detailed investigation of this phenomenon and its underlying mechanism. First, we fed Wistar rats with vitamin E-free diet for 3 days, 1 week, or 2 weeks and found an increase in anxiety-like behavior after 1 and 2 weeks of vitamin E deficiency based on behavioral indicators. Next, we examined the effect of a control diet (150 mg all-racemic α-tocopherol acetate/kg) on anxiety-like behaviors in rats that received a 4- week vitamin E-free diet. We found that increased anxiety-like behavior was reversed to control levels after refeeding vitamin E for 7 days but not for 1 or 3 days. Further, anxiety-like behavior increased or decreased gradually based on the amount of vitamin E intake; however, it had a quicker progression than physical symptoms of vitamin E deficiency. Moreover, rats fed with excess vitamin E (500 mg all-racemic α-tocopherol/kg diet) showed less anxiety-like behavior than control rats, indicating that vitamin E supplementation is effective for preventing anxiety increase under social isolation stress. Since plasma corticosterone levels were higher in vitamin E deficient rats, we investigated the effect of adrenalectomy on anxiety-like behavior and found that adrenal hormones played an essential role in the increased anxiety-like behavior induced by vitamin E deficiency. In conclusion, increased anxiety-like behavior is a symptom that emerges earlier than physical vitamin E deficiency and is caused by adrenal hormone-dependent mechanisms.

Dietary vitamin E deficiency increases anxiety-related behavior in rats under stress of social isolation

BioFactors ◽  
2009 ◽  
Vol 35 (3) ◽  
pp. 273-278 ◽  
Author(s):  
Yuki Okura ◽  
Satoshi Tawara ◽  
Takefumi Kikusui ◽  
Asako Takenaka
Keyword(s):  
Vitamin E ◽  
Social Isolation ◽  
Dietary Vitamin ◽  
Vitamin E Deficiency

Dietary Vitamin E Deficiency Increases Anxiety-Like Behavior in Juvenile and Adult Rats

2011 ◽  
Vol 75 (10) ◽  
pp. 1894-1899 ◽  
Author(s):  
Yuki TERADA ◽  
Yuki OKURA ◽  
Takefumi KIKUSUI ◽  
Asako TAKENAKA
Keyword(s):  
Vitamin E ◽  
Dietary Vitamin ◽  
Vitamin E Deficiency ◽  
Adult Rats

scholarly journals Effects of dietary vitamin E deficiency on systematic pathological changes and oxidative stress in fish

Oncotarget ◽  
2016 ◽  
Vol 7 (51) ◽  
pp. 83869-83879 ◽  
Author(s):  
Kaiyu Wang ◽  
Erlong Wang ◽  
Zhenyang Qin ◽  
Zhen Zhou ◽  
Yi Geng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Dietary Vitamin ◽  
Pathological Changes ◽  
Vitamin E Deficiency ◽  
And Oxidative Stress
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