DOES APPROPRIATE VENOUS THROMBOEMBOLIC PROPHYLAXIS DECREASE VENOUS THROMBOEMBOLIC EVENTS OR RESULT IN INCREASED BLEEDING COMPLICATIONS IN TRAUMA PATIENTS?

2005 ◽  
Vol 33 ◽  
pp. A48
Author(s):  
Katie Burenheide ◽  
W Christopher Bandy
Keyword(s):  
Bleeding Complications ◽  
Trauma Patients ◽  
Thromboembolic Events ◽  
Thromboembolic Prophylaxis ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic

Venous Thromboembolic Events in Pediatric Trauma Patients: Is Prophylaxis Necessary?

2005 ◽  
Vol 59 (6) ◽  
pp. 1345-1349 ◽  
Author(s):  
Michelle C. Azu ◽  
Jane E. McCormack ◽  
Richard J. Scriven ◽  
John S. Brebbia ◽  
Marc J. Shapiro ◽  
...  
Keyword(s):  
Pediatric Trauma ◽  
Trauma Patients ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic

scholarly journals Bleeding complications after systematic switch of routine thromboprophylaxis for major orthopaedic surgery

2008 ◽  
Vol 99 (06) ◽  
pp. 1049-1052 ◽  
Author(s):  
Urs Kistler ◽  
Inès Quervain ◽  
Urs Munzinger ◽  
Nils Kucher
Keyword(s):  
Postoperative Bleeding ◽  
Bleeding Complications ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Major Orthopedic Surgery ◽  
Venous Thromboembolic ◽  
Major Orthopaedic Surgery ◽  
Orthopedic Patients ◽  
Second Period ◽  
Observation Period

SummaryThe rate of bleeding complications after major orthopedic surgery approximates 2%. It is unclear whether a systematic switch of routine thromboprophylaxis has an impact on the rate of postoperative bleeding complications. We analyzed prospectively recorded postoperative bleeding complications and symptomatic venous thromboembolic events in 8,176 consecutive orthopedic patients at the Schulthess Clinic Zurich during a systematic switch of thromboprophylaxis from nadroparin to enoxaparin in the year 2004. Overall, 3,893 patients received nadroparin in the first nine-month observation period before the switch and 4,283 patients received enoxaparin in the second nine-month observation period after the switch. Overall, 96 (2.5%) patients in the first period and 70 (1.6%) patients in the second period suffered a postoperative bleeding complication requiring surgical revision, puncture, or transfusion (p<0.01). Five objectively confirmed symptomatic venous thromboembolic events during hospitalization in the first period and three events in the second period were recorded. In conclusion, the switch of thromboprophylaxis in a large orthopedic clinic did not cause an increase of postoperative bleeding complications and therefore was accompanied by high patient safety.

Dalteparin versus Enoxaparin for the prevention of venous thromboembolic events in trauma patients

2013 ◽  
Vol 40 (2) ◽  
pp. 183-189 ◽  
Author(s):  
O. T. Okoye ◽  
R. Gelbard ◽  
K. Inaba ◽  
M. Esparza ◽  
H. Belzberg ◽  
...  
Keyword(s):  
Trauma Patients ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic

Combined assessment of thrombotic and haemorrhagic risk in acute medical patients

2016 ◽  
Vol 115 (02) ◽  
pp. 392-398 ◽  
Author(s):  
Francesco Orlandini ◽  
Francesca Marchini ◽  
Alessia Marinaro ◽  
Rosanna Bonacci ◽  
Paola Bonanni ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Multivariate Analysis ◽  
High Risk ◽  
Bleeding Complications ◽  
Thromboembolic Events ◽  
Medical Patients ◽  
Pharmacological Prophylaxis ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic ◽  
Supplementary Material

SummaryAcute medical patients have a high risk of venous thromboembolic events (VTE). Unfortunately, the fear of bleeding complications limits the use of antithrombotic prophylaxis in this setting. To stratify the VTE and haemorrhagic risk, two clinical scores (PADUA, IMPROVE) have recently been developed. However, it is not clear how many patients have a concomitant high VTE and haemorrhagic risk and what is the use of prophylaxis in this situation. To clarify these issues we performed a prospective cohort study enrolling consecutive patients admitted to internal medicine. Patients admitted to internal medicine (January to December 2013) were included. VTE and haemorrhagic risk were evaluated in all the included patients. Use and type of anti-thrombotic prophylaxis was recorded. A total of 1761 patients (mean age 77.6 years) were enrolled; 76.8 % (95 % CI 74.7–78.7) were at high VTE risk and 11.9 % (95 % CI 10.4–13.5) were at high haemorrhagic risk. Anti-thrombotic prophylaxis was used in 80.5 % of patients at high VTE risk and in 6.5 % at low VTE risk (p< 0.001), and in 16.6 % at high haemorrhagic risk and in 72.5 % at low haemorrhagic risk (p< 0.001). Prophylaxis was used in 20.4 % at both high VTE and haemorrhagic risk and in 88.9 % at high VTE risk but low haemor-rhagic risk. At multivariate-analysis, use of prophylaxis appeared highly influenced by the VTE risk (OR 68.2, 95 % CI 43.1 - 108.0). In conclusion, many patients admitted to internal medicine were at high risk of VTE. Since almost 90 % of them were at low haemorrhagic risk, pharmacological prophylaxis may be safely prescribed in most of these patients.Supplementary Material to this article is available online at www.thrombosis-online.com.

Impact of marijuana on venous thromboembolic events: Cannabinoids cause clots in trauma patients

2020 ◽  
Vol 89 (1) ◽  
pp. 125-131
Author(s):  
Jack Stupinski ◽  
Letitia Bible ◽  
Samer Asmar ◽  
Mohamad Chehab ◽  
Molly Douglas ◽  
...  
Keyword(s):  
Trauma Patients ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic

The Current Status of Thromboprophylaxis after Trauma: A Story of Confusion and Uncertainty

2006 ◽  
Vol 72 (9) ◽  
pp. 757-763 ◽  
Author(s):  
George C. Velmahos
Keyword(s):  
Molecular Weight ◽  
Pulmonary Embolism ◽  
Standard Of Care ◽  
Current Status ◽  
Low Molecular Weight ◽  
Trauma Patients ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic ◽  
Calf Compression

It is difficult to support a standard of care for venous thromboprophylaxis after trauma when there is no convincing research that any of the currently used methods is consistently effective. Because many conclusions from the nontrauma literature have been misleadingly extrapolated to trauma patients, this review focuses exclusively on trauma articles. These articles present variable results. The rates of deep venous thrombosis and pulmonary embolism are widely different even among similar trauma populations. The heparin-unfractionated or low-molecular-weight and calf compression methods fail to show a reproducible effect in decreasing venous thromboembolic events. The current methods of venous thromboprophylaxis after trauma are inadequate and further research in this area is direly needed.

The incidence of venous thromboembolic events in trauma patients after tranexamic acid administration

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Lisbi Rivas ◽  
Jordan Estroff ◽  
Andrew Sparks ◽  
Jeffry Nahmias ◽  
Rebecca Allen ◽  
...  
Keyword(s):  
Tranexamic Acid ◽  
Trauma Patients ◽  
Thromboembolic Events ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic ◽  
Acid Administration

scholarly journals Recurrence of Upper Extremity Deep Vein Thrombosis Secondary to COVID-19

Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 878
Author(s):  
Yesha H. Parekh ◽  
Nicole J. Altomare ◽  
Erin P. McDonnell ◽  
Martin J. Blaser ◽  
Payal D. Parikh
Keyword(s):  
Deep Vein Thrombosis ◽  
Lower Extremity ◽  
Upper Extremity ◽  
Thromboembolic Events ◽  
Vein Thrombosis ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic ◽  
Deep Vein

Infection with SARS-CoV-2 leading to COVID-19 induces hyperinflammatory and hypercoagulable states, resulting in arterial and venous thromboembolic events. Deep vein thrombosis (DVT) has been well reported in COVID-19 patients. While most DVTs occur in a lower extremity, involvement of the upper extremity is uncommon. In this report, we describe the first reported patient with an upper extremity DVT recurrence secondary to COVID-19 infection.

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