Rapid Response to Psychosocial Treatment for Adolescent Depression: A Two-Year Follow-up

Author(s):  
JOHANNE RENAUD ◽  
DAVID A. BRENT ◽  
MARIANNE BAUGHER ◽  
BORIS BIRMAHER ◽  
DAVID J. KOLKO ◽  
...  
2019 ◽  
Author(s):  
Thomas M Olino ◽  
Daniel Klein ◽  
John Seeley

Background: Most studies examining predictors of onset of depression focus on variable centered regression methods that focus on effects of multiple predictors. In contrast, person-centered approaches develop profiles of factors and these profiles can be examined as predictors of onset. Here, we developed profiles of adolescent psychosocial and clinical functioning among adolescents without a history of major depression. Methods: Data come from a subsample of participants from the Oregon Adolescent Depression Project who completed self-report measures of functioning in adolescence and completed diagnostic and self-report measures at follow-up assessments up to approximately 15 years after baseline. Results: We identified four profiles of psychosocial and clinical functioning: Thriving; Average Functioning; Externalizing Vulnerability and Family Stress; and Internalizing Vulnerability at the baseline assessment of participants without a history of depression at the initial assessment in mid- adolescence. Classes differed in the likelihood of onset and course of depressive disorders, experience of later anxiety and substance use disorders, and psychosocial functioning in adulthood. Moreover, the predictive utility of these classes was maintained when controlling for multiple other established risk factors for depressive disorders. Conclusions: This work highlights the utility of examining multiple factors simultaneously to understand risk for depression.


1996 ◽  
Author(s):  
B. J. McNamara ◽  
T. E. Harrison ◽  
J. Ryan ◽  
R. M. Kippen ◽  
G. J. Fishman ◽  
...  

2011 ◽  
Vol 42 (7) ◽  
pp. 1461-1473 ◽  
Author(s):  
K. Landolt ◽  
W. Rössler ◽  
T. Burns ◽  
V. Ajdacic-Gross ◽  
S. Galderisi ◽  
...  

BackgroundThis study aimed to identify the course of unmet needs by patients with a first episode of schizophrenia and to determine associated variables.MethodWe investigated baseline assessments in the European First Episode Schizophrenia Trial (EUFEST) and also follow-up interviews at 6 and 12 months. Latent class growth analysis was used to identify patient groups based on individual differences in the development of unmet needs. Multinomial logistic regression determined the predictors of group membership.ResultsFour classes were identified. Three differed in their baseline levels of unmet needs whereas the fourth had a marked decrease in such needs. Main predictors of class membership were prognosis and depression at baseline, and the quality of life and psychosocial intervention at follow-up. Depression at follow-up did not vary among classes.ConclusionsWe identified subtypes of patients with different courses of unmet needs. Prognosis of clinical improvement was a better predictor for the decline in unmet needs than was psychopathology. Needs concerning social relationships were particularly persistent in patients who remained high in their unmet needs and who lacked additional psychosocial treatment.


2010 ◽  
Vol 25 (7) ◽  
pp. 396-401 ◽  
Author(s):  
U. Jonsson ◽  
H. Bohman ◽  
A. Hjern ◽  
L. von Knorring ◽  
G. Olsson ◽  
...  

AbstractBackgroundAdolescent depression has been shown to have a range of adverse outcomes. We used longitudinal data to investigate subsequent higher education in former depressed adolescents.MethodA Swedish population-based investigation of depression in 16–17-year-olds was followed up in national registers 15 years later. Adolescents with depression (n = 361, 78% females) were compared to a group of non-depressed peers of the same age (n = 248, 77% females). The main outcome was graduation from higher education by age 30.ResultsThe adolescent with depression were less likely than their non-depressed peers to have graduated from higher education by age 30, both regarding females (27.7% vs. 36.4%, p < .05) and males (12.7% vs. 28.6%, p < .05). After adjustment for early school performance, socioeconomic status and maternal education, the decreased likelihood of subsequent graduation from higher education remained for depressed males (OR, 0.27; 95% CI, 0.08–0.93) but not for depressed females (OR, 0.93; 95% CI, 0.58–1.49).ConclusionContrary to what previous research has suggested, adolescent depression and its consequences might be particularly destructive to subsequent higher education in males.


2020 ◽  
Author(s):  
Lindsey Jones ◽  
Eduardo F. Salgado ◽  
Matthew C. Aalsma ◽  
Jennifer M. Garabrant ◽  
Julie K. Staples ◽  
...  

Abstract Background: Mind-Body Skills Groups (MBSGs) have shown promise in reducing adolescent depression symptoms; however, little is known about adolescents’ perspectives on this treatment. The objective of this study was to understand the acceptability of a new treatment for depressed adolescents in primary care settings. Methods: Adolescents participating in a 10-week MBSG treatment were interviewed to understand their perspectives on the acceptability and effectiveness of the treatment. Interviews were collected at post-intervention and at a 3-month follow-up visit. Results: A total of 39 adolescents completed both the post-intervention and 3-month follow-up interview. At post-intervention and follow-up, 84% of adolescents stated the MBSGs helped them. When asked how the MBSGs helped them, 3 areas were identified: learning new MBSG activities and skills, social connection with others within the group, and outcomes related to the group. Many adolescents reported no concerns with the MBSGs (49% at post- intervention; 62% at follow-up). Those with concerns identified certain activities as not being useful, wanting the group to be longer, and the time of group (after school) being inconvenient. Most adolescents reported that their life had changed because of the group (72% at post-intervention; 61% at follow-up), and when asked how, common responses included feeling less isolated and more hopeful. Conclusions: Adolescents found the MBSGs to be helpful and acceptable as a treatment option for depression in primary care. Given the strong emphasis on treatment preference autonomy and the social activities within the group, MBSGs appear well-suited for this age group. Trial Registration: NCT03363750


2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
S Brolin Låftman ◽  
R Ssegonja ◽  
I Alaie ◽  
U Jonsson ◽  
H Bohman

Abstract Background Alcohol abuse often co-occurs with adolescent depression and about 1-2% suffer from the dual diagnosis in adolescence. This group is often undertreated or receive inadequate treatment for either of the conditions. Both conditions affect the developing brain and poor long-term outcome might be a potential risk. Yet, long-term follow-up studies are scarce. The aim of this study was to analyse if adolescent depression and alcohol abuse predict poorer mental health in adulthood compared to individuals without either or both conditions. Methods A community-based sample of individuals with adolescent depression in 1991-93 and matched non-depressed peers were followed up using a structured diagnostic interview after 15 years. The participation rate was 65% (depressed n = 227; non-depressed controls n = 155). Information on alcohol abuse in adolescence was collected at baseline with a structured interview. The outcome was mental disorders between the ages 19-31 years; information on depression and alcohol abuse was collected at the follow-up with a structured diagnostic interview. The statistical method used was binary logistic regression. Results Adolescents with depression and alcohol abuse had an excess risk of recurrence of depression (OR 2.12, p &lt; 0.05) and alcohol abuse (OR 6.72, p &lt; 0.01) in adulthood, compared with adolescents with depression only, even when adjusted for confounders. Adolescents with alcohol abuse only had not significantly worse long-term outcome compared with their healthy peers. Conclusions The co-occurrence of depression and alcohol abuse in adolescence is associated with long-lasting health consequences compared to either condition alone. This finding indicates that there is a need to prioritize this group of patients that is at risk of suboptimal treatment, and to further develop effective treatment adjusted to the co-occurring condition. Key messages The co-occurrence of adolescent depression and alcohol abuse has long lasting mental health consequences compared to either condition alone. Improved treatment methods are important for this group of adolescents.


10.2196/13628 ◽  
2019 ◽  
Vol 21 (8) ◽  
pp. e13628 ◽  
Author(s):  
Marie Bee Hui Yap ◽  
Mairead C Cardamone-Breen ◽  
Ronald M Rapee ◽  
Katherine A Lawrence ◽  
Andrew J Mackinnon ◽  
...  

Background Prevention of depression and anxiety disorders early in life is a global health priority. Evidence on risk and protective factors for youth internalizing disorders indicates that the family represents a strategic setting to target preventive efforts. Despite this evidence base, there is a lack of accessible, cost-effective preventive programs for parents of adolescents. To address this gap, we recently developed the Partners in Parenting (PiP) program—an individually tailored Web-based parenting program targeting evidence-based parenting risk and protective factors for adolescent depression and anxiety disorders. We previously reported the postintervention outcomes of a single-blinded parallel-group superiority randomized controlled trial (RCT) in which PiP was found to significantly improve self-reported parenting compared with an active-control condition (educational factsheets). Objective This study aimed to evaluate the effects of the PiP program on parenting risk and protective factors and symptoms of adolescent depression and anxiety using data from the final assessment time point (12-month follow-up) of this RCT. Methods Parents (n=359) and adolescents (n=332) were recruited primarily from secondary schools and completed Web-based assessments of parenting and adolescent depression and anxiety symptoms at baseline, postintervention (3 months later), and 12-month follow-up (317 parents, 287 adolescents). Parents in the PiP intervention condition received personalized feedback about their parenting and were recommended a series of up to 9 interactive modules. Control group parents received access to 5 educational factsheets about adolescent development and mental health. Both groups received a weekly 5-min phone call to encourage progress through their program. Results Intervention group parents completed an average of 73.7% of their intended program. For the primary outcome of parent-reported parenting, the intervention group showed significantly greater improvement from baseline to 12-month follow-up compared with controls, with a medium effect size (Cohen d=0.51; 95% CI 0.30 to 0.72). When transformed data were used, greater reduction in parent-reported adolescent depressive symptoms was observed in the intervention group (Cohen d=−0.21; 95% CI −0.42 to −0.01). Mediation analyses revealed that these effects were mediated by improvements in parenting (indirect effect b=−0.08; 95% CI −0.16 to −0.01). No other significant intervention effects were found for adolescent-reported parenting or adolescent depression or anxiety symptoms. Both groups showed significant reductions in anxiety (both reporters) and depressive (parent reported) symptoms. Conclusions PiP improved self-reported parenting for up to 9 months postintervention, but its effects on adolescent symptoms were less conclusive, and parent-reported changes were not perceived by adolescents. Nonetheless, given its scalability, PiP may be a useful low-cost, sustainable program to empower parents of adolescents. Trial Registration Australian Clinical Trials Registration Number (ACTRN): 12615000328572; http://www.anzctr.org.au/ACTRN12615000328572.aspx (Archived by WebCite at http://www.webcitation.org/6qgsZ3Aqj).


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