Central nervous system anomalies associated with meningomyelocele, hydrocephalus, and the Arnold-Chiari malformation

Neurosurgery ◽  
1986 ◽  
Vol 18 (5) ◽  
pp. 559???64 ◽  
Author(s):  
J N Gilbert ◽  
K L Jones ◽  
L B Rorke ◽  
G F Chernoff ◽  
H E James
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chiari Malformation ◽  
Arnold Chiari Malformation ◽  
Central Nervous System Anomalies

scholarly journals ARNOLD-CHIARI MALFORMATION: LITERATURE REVIEW AND CLINICAL CASE IN SIBLINGS

2021 ◽  
Vol 11 (1(39)) ◽  
pp. 58-64
Author(s):  
Anastasiya Babintseva ◽  
Yu.Yu. Khodzinska ◽  
І.V. Lastivka ◽  
О.І. Yurkiv ◽  
A.I. Roshka ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chiari Malformation ◽  
Clinical Case ◽  
Type Ii ◽  
Hernia Sac ◽  
Arnold Chiari Malformation ◽  
System Type ◽  
The Central Nervous System ◽  
The Brain

Arnold-Chiari malformation is a defectof the cervical-medullar transition characterized bydisplacement of the cerebellar tonsils and in a numberof cases when the stem and IV ventricle extend into theforamen magnum. There are four main types of pathology,and type II is found most often.The article presents a clinical case of type II ArnoldChiari malformation in siblings. The newborn girl born afterVII pregnancy and VII physiological delivery in the termof 39-40 weeks was under observation. US examination inthe terms of 20-21 and 34 weeks of gestation diagnoseda congenital developmental defect of the central nervoussystem characterized by a “lemon”-like shape of the brain,displacement of the brain structures in the portion of theforamen magnum, ventriculomegaly, a defect of the lumbarsacral portion with formation of hernia sac, and dropsy ofamnion. The family couple refused from interruption ofpregnancy and medical-genetic examination.The basic diagnosis of the child was congenitaldevelopmental defect of the central nervous system(type II Arnold-Chiari malformation: rachischisis andhydrocephalus) including complications such as inferiortorpid paraplegia and dysfunction of the pelvic organs.Investigation of hereditary anamnesis foundcompromised heredity on the mother’s side (her mother’ssibling has Down’s syndrome), and IV child in the familyis disabled from birth due to a congenital developmentaldefect of the central nervous system – type II Arnold-Chiarimalformation.The family couple refused from a comprehensivemedical-genetic consultation during the previous andcurrent pregnancies, and magnetic-resonance imaging ofthe child.

Central Nervous System Anomalies Associated with Meningomyelocele, Hydrocephalus, and the Arnold-Chiari Malformation: Reappraisal of Theories Regarding the Pathogenesis of Posterior Neural Tube Closure Defects

Neurosurgery ◽  
1986 ◽  
Vol 18 (5) ◽  
pp. 559-564 ◽  
Author(s):  
James N. Gilbert ◽  
Kenneth L. Jones ◽  
Lucy B. Rorke ◽  
Gerald F. Chernoff ◽  
Hector E. James
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neural Tube ◽  
Cortical Neurons ◽  
Chiari Malformation ◽  
Neural Tube Closure ◽  
Arnold Chiari Malformation ◽  
Wide Range ◽  
Tube Closure ◽  
Neural Tube Closure Defects

Abstract Complete gross and microscopic neuropathological examinations of 25 children who died with meningomyelocele, the Arnold-Chiari malformation, and hydrocephalus revealed a wide range and frequency of associated central nervous system malformations. The most remarkable of these anomalies were hypoplasia or aplasia of cranial nerve nuclei (20%), demonstrable obstruction of cerebrospinal fluid flow within the ventricular system (92%), cerebellar dysplasia (72%), a disorder of migration of cortical neurons (92%), fusion of the thalami (16%), agenesis of the corpus callosum (12%), and complete or partial agenesis of the olfactory tract and bulb (8%). The anomalies associated with posterior neural tube closure defects can no longer be considered secondary, but rather must be considered part of a spectrum of malformations caused by an unidentified primary insult to the central nervous system. The frequency and pattern of brain malformations associated with neural tube defects of some children with meningomyelocele suggest that such malformations may seriously affect intellectual outcome.

Fetal Central Nervous System Anomalies According to RT-PCR and Trimester of Maternal Infection with ZIKV. A Prospective Study

2020 ◽  
Author(s):  
Luz Ángela Gutiérrez-Sánchez ◽  
Carlos Hernán Becerra-Mojica ◽  
Mario Augusto Rojas ◽  
Luis Alfonso Díaz-Martínez ◽  
Luis Alfonso Pérez-Vera ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prospective Study ◽  
Maternal Infection ◽  
Rt Pcr ◽  
A Prospective Study ◽  
Central Nervous System Anomalies

Central nervous system anomalies in two females with Borjeson-Forssman-Lehmann syndrome

2017 ◽  
Vol 69 ◽  
pp. 104-109 ◽  
Author(s):  
Burkhard S. Kasper ◽  
Arnd Dörfler ◽  
Nataliya Di Donato ◽  
Ekkehard M. Kasper ◽  
Dagmar Wieczorek ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Anomalies

scholarly journals A Rare Case of Pericallosal Lipoma Associated with Bilaterally Symmetrical Lateral Ventricular Choroid Plexus Lipomas without Corpus Callosal Anomalies

2013 ◽  
Vol 3 ◽  
pp. 69 ◽  
Author(s):  
Parag Suresh Mahajan ◽  
Nawal M. Al Moosawi ◽  
Islam Ali Hasan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumors ◽  
Corpus Callosum ◽  
Choroid Plexus ◽  
Rare Case ◽  
Rare Presentation ◽  
Pericallosal Lipoma ◽  
Central Nervous System Anomalies

Lipomas constitute less than 5% of primary brain tumors. Pericallosal lipomas (PCLp) constitute almost half of all intracranial lipomas. Corpus callosal anomalies commonly occur in cases with PCLps. Although PCLp is often described as corpus callosal lipoma, it is most often pericallosal in location. PCLps may have calcification in the periphery and may continue into lateral ventricles, which is a very rare presentation. We observed a case of PCLp with peripheral calcifications associated with PCLp continuing as bilaterally symmetrical lateral ventricular choroid plexus lipomas (CPLp) without any corpus callosal or other central nervous system anomalies, and as this is not been previously reported, we are presenting it. The appearance of PCLp in this case does not correspond to the descriptions of any of the existing morphological types (anterior and posterior) of classification of PCLps; it is rather mixed, where PCLp occupies both anterior and posterior locations around the corpus callosum.

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