scholarly journals A Rare Case of Pericallosal Lipoma Associated with Bilaterally Symmetrical Lateral Ventricular Choroid Plexus Lipomas without Corpus Callosal Anomalies

2013 ◽  
Vol 3 ◽  
pp. 69 ◽  
Author(s):  
Parag Suresh Mahajan ◽  
Nawal M. Al Moosawi ◽  
Islam Ali Hasan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumors ◽  
Corpus Callosum ◽  
Choroid Plexus ◽  
Rare Case ◽  
Rare Presentation ◽  
Pericallosal Lipoma ◽  
Central Nervous System Anomalies

Lipomas constitute less than 5% of primary brain tumors. Pericallosal lipomas (PCLp) constitute almost half of all intracranial lipomas. Corpus callosal anomalies commonly occur in cases with PCLps. Although PCLp is often described as corpus callosal lipoma, it is most often pericallosal in location. PCLps may have calcification in the periphery and may continue into lateral ventricles, which is a very rare presentation. We observed a case of PCLp with peripheral calcifications associated with PCLp continuing as bilaterally symmetrical lateral ventricular choroid plexus lipomas (CPLp) without any corpus callosal or other central nervous system anomalies, and as this is not been previously reported, we are presenting it. The appearance of PCLp in this case does not correspond to the descriptions of any of the existing morphological types (anterior and posterior) of classification of PCLps; it is rather mixed, where PCLp occupies both anterior and posterior locations around the corpus callosum.

scholarly journals Adult medulloblastoma

2016 ◽  
Vol 30 (4) ◽  
pp. 557-561
Author(s):  
S.V. Rege ◽  
Harshad Patil ◽  
Sharadendu Narayan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumors ◽  
Rare Case ◽  
Adult Brain ◽  
Cns Tumor ◽  
Adult Medulloblastoma ◽  
Cerebellar Medulloblastoma

Abstract Medulloblastoma is a highly malignant central nervous system (CNS) tumor that arises from the cerebellum. It is the most common primary malignant intracranial childhood neoplasm. In adults, medulloblastoma are much less common, accounting for < 1% of all adult brain tumors. Herein, author has described a rare case of cerebellar medulloblastoma in adult.

scholarly journals Fourth ventricular ependymoma with a distant intraventricular metastasis: Report of a rare case

2013 ◽  
Vol 04 (S 01) ◽  
pp. S121-S124 ◽  
Author(s):  
Sudheer Ambekar ◽  
Manish Ranjan ◽  
Sampath Somanna ◽  
Chandrajit Prasad ◽  
Vani Santosh
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Primary Tumor ◽  
Rare Case ◽  
Age Group ◽  
Anaplastic Ependymoma ◽  
Rare Presentation ◽  
Adult Age ◽  
The Central Nervous System

ABSTRACTEpendymoma is one of the uncommon tumors of the central nervous system (CNS) in the adult age group. These tumors have a distinct propensity for metastasis, both within and outside the CNS. However, dissemination at the time of first presentation and retrograde dissemination of the tumor is rare. We report the case of a patient with fourth ventricular anaplastic ependymoma who presented with left lateral ventricular metastasis which was anatomically different from the primary tumor. We describe the clinic‑pathological detail of the patient and discuss the probable pathophysiological basis for this rare presentation and its significance in management of the patient.

Surgical Neuropathology Update: A Review of Changes Introduced by the WHO Classification of Tumours of the Central Nervous System, 4th Edition

2008 ◽  
Vol 132 (6) ◽  
pp. 993-1007 ◽  
Author(s):  
Daniel J. Brat ◽  
Joseph E. Parisi ◽  
Bette K. Kleinschmidt-DeMasters ◽  
Anthony T. Yachnis ◽  
Thomas J. Montine ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumors ◽  
Who Classification ◽  
World Health ◽  
Central Nervous System Neoplasms ◽  
Genetic Syndrome ◽  
Blue Book ◽  
The Central Nervous System

Abstract Context.—The World Health Organization (WHO) recently published its 4th edition of the classification of tumors of the central nervous system, incorporating a substantial number of important changes to the previous version (WHO 2000). The new WHO classification introduces 7 changes in the grading of central nervous system neoplasms, ranging in significance from minor to major, in categories of anaplastic oligoastrocytomas, meningiomas, choroid plexus tumors, pineal parenchymal tumors, ganglioglioma, cerebellar liponeurocytoma, and hemangiopericytomas. The 4th edition also introduces 10 newly codified entities, variants, and patterns, as well as 1 new genetic syndrome. A number of established brain tumors are reorganized, including medulloblastomas and primitive neuroectodermal tumors, in an attempt to more closely align classification with current understanding of central nervous system neoplasia. Objective.—To summarize and discuss the most significant updates in the 4th edition for the practicing surgical pathologist, including (1) changes in grading among established entities; (2) newly codified tumor entities, variants, patterns, and syndromes; and (3) changes in the classification of existing brain tumors. Data Sources.—The primary source for this review is the WHO Classification of Tumours of the Central Nervous System, 4th edition. Other important sources include the 3rd edition of this book and the primary literature that supported changes in the 4th edition. Conclusions.—The new edition of the WHO blue book reflects advancements in the understanding of brain tumors in terms of classification, grading, and new entities. The changes introduced are substantial and will have an impact on the practice of general surgical pathologists and neuropathologists.

scholarly journals PS2 - 195 Integrating Molecular Workings into the World Health Organization (WHO) Classification of Tumours of the Central Nervous System: A Survey from the Neuro-Oncology Community

2016 ◽  
Vol 43 (S4) ◽  
pp. S16-S16
Author(s):  
R. Nejad ◽  
D.N. Louis ◽  
K. Aldape ◽  
G. Zadeh
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Markers ◽  
Brain Tumors ◽  
Who Classification ◽  
Strong Support ◽  
Molecular Classification ◽  
World Health ◽  
The Central Nervous System

Tumours of the central nervous system are currently classified based on the 2007 WHO Classification of Tumours, which uses histological features to classify and grade these heterogeneous tumors. With recent advances in the development of clinically relevant molecular signatures, there is an interest to incorporate appropriate molecular markers in to the classification. The views of the neuro-oncology community on such changes would be informative for advising this process. METHODS A survey with 8 questions regarding molecular markers in tumor classification was sent to an email list of Society of Neuro-Oncology members and attendees of prior meetings (n=5065). There were 403 respondents. Analysis was performed using whole group response and based on self-reported sub-specialty. RESULTS Survey results among all respondents show support for incorporating our molecular knowledge of brain tumors into the WHO classification (>80%). As one example, 96% of respondents responded that the integration of 1p/19q co-deletion into the molecular classification of oligodendroglioma was “very” or “critically” important for the management of grade III gliomas. While 30% of all respondents believe that IDH mutation status should affect overall management of GBM. Interestingly, there was some variability among sub-specialties for certain aspects, and as one example neuropathologists were slightly more inclined to disagree that molecular markers should be included in the WHO classification (25% for neuropathologists versus 13% overall). CONCLUSION Based on a survey provided to the neuro-oncology community, we report strong support for the integration of molecular markers into the WHO classification of brain tumors, as well as for using an integrated “layered” diagnostic format.

Fetal Central Nervous System Anomalies According to RT-PCR and Trimester of Maternal Infection with ZIKV. A Prospective Study

2020 ◽  
Author(s):  
Luz Ángela Gutiérrez-Sánchez ◽  
Carlos Hernán Becerra-Mojica ◽  
Mario Augusto Rojas ◽  
Luis Alfonso Díaz-Martínez ◽  
Luis Alfonso Pérez-Vera ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prospective Study ◽  
Maternal Infection ◽  
Rt Pcr ◽  
A Prospective Study ◽  
Central Nervous System Anomalies

scholarly journals Beyond Oncological Hyperthermia: Physically Drivable Magnetic Nanobubbles as Novel Multipurpose Theranostic Carriers in the Central Nervous System

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2104 ◽  
Author(s):  
Eleonora Ficiarà ◽  
Shoeb Anwar Ansari ◽  
Monica Argenziano ◽  
Luigi Cangemi ◽  
Chiara Monge ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumors ◽  
Ad Hoc ◽  
Superparamagnetic Iron Oxide ◽  
Conventional Radiotherapy ◽  
The Central Nervous System ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Magnetic Oxygen-Loaded Nanobubbles (MOLNBs), manufactured by adding Superparamagnetic Iron Oxide Nanoparticles (SPIONs) on the surface of polymeric nanobubbles, are investigated as theranostic carriers for delivering oxygen and chemotherapy to brain tumors. Physicochemical and cyto-toxicological properties and in vitro internalization by human brain microvascular endothelial cells as well as the motion of MOLNBs in a static magnetic field were investigated. MOLNBs are safe oxygen-loaded vectors able to overcome the brain membranes and drivable through the Central Nervous System (CNS) to deliver their cargoes to specific sites of interest. In addition, MOLNBs are monitorable either via Magnetic Resonance Imaging (MRI) or Ultrasound (US) sonography. MOLNBs can find application in targeting brain tumors since they can enhance conventional radiotherapy and deliver chemotherapy being driven by ad hoc tailored magnetic fields under MRI and/or US monitoring.

scholarly journals Central Nervous System Vasculitis as a Rare Presentation of Mycoplasma pneumoniae: A Case Report

2020 ◽  
Vol 12 (3) ◽  
pp. 402-409
Author(s):  
Ashraf Omer Elamin Ahmed ◽  
Mona Mohammad Ibraheem Babikir ◽  
Amir Elssoni Mahjoup Khojali ◽  
Suresh Nalaka Menik Arachchige ◽  
Abdirahman Mohamud Abdirahman ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Central Nervous System Involvement ◽  
Lower Respiratory Tract Infections ◽  
Central Nervous System Vasculitis ◽  
Rare Presentation ◽  
Systemic Involvement ◽  
Tract Infections

<i>Mycobacteria pneumoniae</i> (MP) commonly causes upper and lower respiratory tract infections. The clinical manifestation is classified as pulmonary and extrapulmonary. These manifestations vary according to the involved system. MP may affect one system or more at a time. Commonly prodromal respiratory symptoms precede systemic involvement. Central nervous system involvement in uncommon. This report is presenting a rare case of central nervous system vasculitis secondary to MP, highlighting the diagnosis and management with a succinct literature review.

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