Impact of betel quid, tobacco and alcohol on three-stage disease natural history of oral leukoplakia and cancer: implication for prevention of oral cancer

2004 ◽  
Vol 13 (1) ◽  
pp. 39-45 ◽  
Author(s):  
M-N Shiu ◽  
TH-H Chen
2021 ◽  
Vol 11 ◽  
Author(s):  
Andrew H. Nguyen ◽  
Michael P. O’Leary ◽  
James P. De Andrade ◽  
Philip H. G. Ituarte ◽  
Jonathan Kessler ◽  
...  

Renal neuroendocrine neoplasms are rare, with descriptions of cases limited to individual reports and small series. The natural history of this group of neuroendocrine neoplasms is poorly understood. In this study, we queried the Surveillance, Epidemiology and End Results (SEER) database over a four-decade period where we identified 166 cases of primary renal neuroendocrine neoplasms. We observed a 5-year overall survival of 50%. On multivariate analysis, survival was influenced by stage, histology, and if surgery was performed. We observed that patients managed by operative management had a greater frequency of localized or regional stage disease as well as a greater frequency of neuroendocrine tumor, grade 1 histology; whereas those managed non-operatively tended to have distant disease and histologies of neuroendocrine carcinoma, NOS and small cell neuroendocrine carcinoma. This is the largest description of patients with renal neuroendocrine neoplasms. Increased survival was observed in patients with earlier stage and favorable histologies.


Cancer ◽  
1976 ◽  
Vol 38 (4) ◽  
pp. 1790-1795 ◽  
Author(s):  
Sol Silverman ◽  
K. Bhargava ◽  
N. J. Mani ◽  
Lowell W. Smith ◽  
A. M. Malaowalla

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.


2001 ◽  
Vol 120 (5) ◽  
pp. A128-A128 ◽  
Author(s):  
H MALATY ◽  
D GRAHAM ◽  
A ELKASABANY ◽  
S REDDY ◽  
S SRINIVASAN ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document