Local Heating Test for Detection of Microcirculation Abnormalities in Patients with Diabetes-Related Foot Complications

BACKGROUND: Neurogenic regulation is involved in the development of microcirculation response to local heating. We suggest that microvascular reactivity can be used to estimate the severity of diabetic polyneuropathy (DPN). OBJECTIVE: To evaluate the prospects for using the parameters of skin microvascular reactivity to determine the severity of DPN. METHODS: 26 patients with diabetes mellitus were included in the study (patients with retinopathy (n = 15), and without retinopathy (n = 11)). The severity of DPN was assessed using Michigan Neuropathy Screening Instrument (MNSI) and Norfolk QOL-DN (NQOLDN). Skin microcirculation was measured by laser Doppler flowmetry with local heating test. RESULTS: There were revealed moderate negative correlations between microvascular reactivity and the severity of DPN (for MNSI (Rs = –0.430), for NQOLDN (Rs = –0.396)). In patients with retinopathy, correlations were stronger than in the general group (for MNSI (Rs = –0.770) and NQOLDN (Rs = –0.636)). No such correlations were found in patients without retinopathy. CONCLUSION: Correlation of the microvascular reactivity and DPN was revealed in patients with registered structural disorders in microvessels (retinopathy). The lack of such correlation in patients without retinopathy may be explained by the intact compensatory mechanisms of microvessels without severe disorders.

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Causation Research on Diabetic Foot Complications—What I Learned From Roger Pecoraro: The 2021 Roger E. Pecoraro Award Lecture

10.2337/figshare.15048282 ◽

2021 ◽

Author(s):

Edward J. Boyko

Keyword(s):

Risk Factors ◽

Diabetic Foot ◽

Past History ◽

Foot Ulcer ◽

Diabetic Foot Ulcer ◽

Clinical Information ◽

Arterial Perfusion ◽

Primary Care Population ◽

Foot Complications ◽

Patients With Diabetes

Roger Pecoraro made important contribution to diabetic foot research and is primarily responsible for instilling in me an interest in these complications. Our collaboration in the final years of his life led to the development of the Seattle Diabetic Foot Study. At the time it began, the Seattle Diabetic Foot Study was perhaps unique in being a prospective study of diabetic foot ulcer conducted in a non-specialty primary care population of patients with diabetes and without foot ulcer. Important findings from this research include the demonstration that neurovascular measurements, diabetes characteristics, past history of ulcer or amputation, body weight, and poor vision all significantly and independently predict foot ulcer risk. A prediction model from this research that included only readily available clinical information showed excellent ability to discriminate between patients who did and did not develop ulcer during follow-up (area under ROC curve=0.81 at one year). Identification of limb-specific amputation risk factors showed considerable overlap with those risk factors identified for foot ulcer, but suggested arterial perfusion as playing a more important role. Risk of foot ulcer in relation to peak plantar pressure estimated at the site of the pressure measurement showed a significant association over the metatarsal heads, but not other foot locations, suggesting that the association between pressure and this outcome may differ by foot location. The Seattle Diabetic Foot Study has helped to expand our knowledge base on risk factors and potential causes of foot complications. Translating this information into preventive interventions remains a continuing challenge.

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Foot Self Efficacy dan Foot Self Care Behaviour pada Lansia dengan Diabetes Melitus

JI-KES (Jurnal Ilmu Kesehatan) ◽

10.33006/ji-kes.v3i1.126 ◽

2019 ◽

Vol 3 (1) ◽

pp. 12-18

Author(s):

Ainul Yaqin Salam ◽

Nur Hamim

Keyword(s):

Self Efficacy ◽

Self Care ◽

Cross Sectional Study ◽

Foot Care ◽

Cross Sectional ◽

Foot Complications ◽

Patients With Diabetes ◽

Main Determinants ◽

And Gender ◽

Care Behavior

AbstrakLansia dengan diabetes adalah kelompok khusus yang memiliki resiko tinggi komplikasipada kakinya. Self-efficacymenjadi salah satu determinan faktor utama untuk meningkatkan perilaku perawatan kaki. Penelitian ini bertujuan untuk mengidentifikasi tingkat efikasi diri kaki (Foot Self Efficacy) dan perilaku perawatan kaki (Foot Crae Behaviour) dan hubungannya dengan karakteristik demografis pada lansia dengan diabetes.Studi cross-sectional digunakandi Desa Karangren Kecamatan Krejengan Probolinggo dari Mei hingga Juni 2019. Kriteria khusus dipilih untuk berpartisipasi dalam penelitian ini. Para responden diwawancarai menggunakan seperangkat kuesioner yang telah divalidasi. Statistik deskriptif dan inferensial (regresi linier berganda) digunakan untuk menjawab hipotesis penelitiandengan bantuanSPSS 19. Hasil penelitian menyebutkan rata-ratafoot self-efficacysebesar 29,79 dengan standar deviasi 8,26 danrata-ratafoot care behavior sebesar 28,72 dengan SD 6,33. Terdapat hubungan positif dan signifikan antara foot self-efficacy (β = 0,43, p <0,001), tingkat pendidikan (β = 0,43, p <0,001), dan jenis kelamin (β = 0,31, p <0,001) dengan perilaku perawatan kaki. Program edukasi self-efficacydapat menjadi pertimbangan yang krusial untuk meningkatkan perilaku perawatan kaki. Lansia dengan diabetes harus diajari pemeriksaan kaki secara mandiri.Perawatan kaki diabetes yang tepat dan berkelanjutan dapat secara signifikan mencegah terjadinya komplikasi pada kaki lebih lanju yang berefek pada peningkatan kualitas hidup. Kata kunci: diabetes, lansia, efikasi diri, perilaku perawatan diri, kaki AbstractThe elderly with diabetes is a special group that has a high risk of complications in the legs. Self-efficacy is one of the main determinants of improving foot care behavior.The essential aims of this study were to identify the level of self-efficacy and foot care behavior and its relationship to demographic characteristics in elderly patients with diabetes. The cross-sectional study has been done in Karangren Village, Krejengan Probolinggo district from May to June 2019. Specific criteria were chosen to participate in this study. The respondents interviewed used a set of validated questionnaires. Descriptive and inferential statistics (multiple linear regression) were used to answer the research hypothesisby SPSS 19. The results mentioned that the average foot self-efficacy was 29.79, with a standard deviation of 8.26, and the normal foot care behavior was 28.72, with an SD of 6.33. There is a significant relationship between foot self-efficacy (β = 0.43, p <0.001), level of education (β = 0.43, p <0.001), and gender (β = 0.31, p <0.001) with foot care behavior. The self-efficacy education program can be a crucial considerateness for improving foot care behavior.Elderly with diabetes must be taught foot examinations independently. Appropriate and ongoing diabetes foot care can significantly prevent diabetic foot complications, which affect improving the quality of life. Keywords: diabetes, elderly, self-efficacy, self-care behavior, feet

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Foot complications in patients with diabetes

Surgery (Oxford) ◽

10.1016/j.mpsur.2016.02.005 ◽

2016 ◽

Vol 34 (4) ◽

pp. 192-197 ◽

Cited By ~ 1

Author(s):

Clifford P. Shearman ◽

Majd Rawashdeh

Keyword(s):

Foot Complications ◽

Patients With Diabetes

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Foot complications in patients with diabetes

Surgery (Oxford) ◽

10.1016/j.mpsur.2018.12.003 ◽

2019 ◽

Vol 37 (2) ◽

pp. 106-111 ◽

Cited By ~ 1

Author(s):

Ffion Dewi ◽

Robert J. Hinchliffe

Keyword(s):

Foot Complications ◽

Patients With Diabetes

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Foot complications in patients with diabetes

Surgery (Oxford) ◽

10.1016/j.mpsur.2010.02.002 ◽

2010 ◽

Vol 28 (6) ◽

pp. 288-292 ◽

Cited By ~ 3

Author(s):

Clifford P. Shearman ◽

Robin Windhaber

Keyword(s):

Foot Complications ◽

Patients With Diabetes

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Laser therapy for onychomycosis in patients with diabetes at risk for foot complications: study protocol for a randomized, double-blind, controlled trial (LASER-1)

Trials ◽

10.1186/s13063-015-0622-4 ◽

2015 ◽

Vol 16 (1) ◽

Cited By ~ 8

Author(s):

Leonie Nijenhuis-Rosien ◽

Nanne Kleefstra ◽

Maurice J Wolfhagen ◽

Klaas H Groenier ◽

Henk JG Bilo ◽

...

Keyword(s):

At Risk ◽

Laser Therapy ◽

Study Protocol ◽

Controlled Trial ◽

Double Blind ◽

Foot Complications ◽

Patients With Diabetes

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A STUDY TO ASSESS THE KNOWLEDGE, ATTITUDE AND PRACTICE REGARDING PREVENTION OF FOOT COMPLICATIONS AMONG PATIENTS WITH DIABETES MELLITUS BEFORE AND AFTER VIDEO ASSITED PROGRAMME

THE RESEARCH RESERVOIR ◽

10.47211/trr.2019.v05i02.015 ◽

2019 ◽

Vol 5 (2) ◽

pp. 81-86

Author(s):

Rosemine Kiruba Darwin ◽

Dr. Santhi Appavu

Keyword(s):

Diabetes Mellitus ◽

Attitude And Practice ◽

Foot Complications ◽

Before And After ◽

Patients With Diabetes ◽

Knowledge Attitude And Practice

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Diabetes and endocrine emergencies

Oxford Handbook of Acute Medicine ◽

10.1093/med/9780198797425.003.0009 ◽

2019 ◽

pp. 545-606

Author(s):

Punit S. Ramrakha ◽

Kevin P. Moore ◽

Amir H. Sam

Keyword(s):

Malignant Hyperthermia ◽

Diabetic Ketoacidosis ◽

Neuroleptic Malignant Syndrome ◽

Diabetic Foot ◽

Pituitary Apoplexy ◽

Urgent Surgery ◽

Foot Complications ◽

Patients With Diabetes ◽

Thyrotoxic Crisis ◽

Hypoglycaemic Coma

This chapter describes diabetes and endocrine emergencies, including diabetic ketoacidosis (DKA; assessment, management, complications), hyperosmolar non-ketotic coma (HONK), hypoglycaemic coma, urgent surgery in patients with diabetes, diabetic foot complications, hyponatraemia, hypernatraemia, acute hypocalcaemia, hypercalcaemia, hypophosphataemia, Addisonian crisis, myxoedema coma, thyrotoxic crisis, pituitary apoplexy, hypopituitary coma, phaeochromocytomas, polyuria, malignant hyperthermia, and neuroleptic malignant syndrome.

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