Comparing Human Amniotic Allograft and Standard Wound Care When Using Total Contact Casting in the Treatment of Patients with Diabetic Foot Ulcers

2019 ◽  
Vol 32 (6) ◽  
pp. 272-277 ◽  
Author(s):  
Patricia Thompson ◽  
Darlene S. Hanson ◽  
Diane Langemo ◽  
Julie Anderson
Keyword(s):  
Diabetic Foot ◽  
Wound Care ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Total Contact Casting

Diabetic Foot Ulcers: The Importance of Patient Comorbidity Recognition and Total Contact Casting in Successful Wound Care

2016 ◽  
Vol 82 (8) ◽  
pp. 733-736 ◽  
Author(s):  
Mayuri Jagadish ◽  
Michael M. Mcnally ◽  
R. Eric Heidel ◽  
Susan Teffeteller ◽  
Joshua D. Arnold ◽  
...  
Keyword(s):  
Wound Healing ◽  
Deep Vein Thrombosis ◽  
Diabetic Foot ◽  
Wound Care ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Population Total ◽  
Vein Thrombosis ◽  
Total Contact Casting ◽  
Deep Vein

Diabetic foot ulcers (DFUs) are a major burden on the health-care system. The purpose of this study is to investigate factors affecting the healing rate of DFU in a university wound care center. Records of DFU patients treated between July 2013 and February 2015 were reviewed. Demographics, comorbidities, wound characteristics, and treatment modalities including offloading, hyperbaric oxygen treatment, total contact casting, and bioengineered skin were investigated. All patients underwent weekly debridement regardless of treatment modality. A total of 114 patients ages 18 to 98 comprised the study population. Total contact casting was the only treatment associated with increased healing ( P = 0.02). Smoking ( P = 0.004) and deep vein thrombosis history ( P = 0.001) significantly decreased the likelihood of wound healing. Patients with past vascular event trended toward longer healing times ( P = 0.07). Total contact casting in combination with weekly wound debridement showed benefit in DFU wound healing, whereas patients with a history of deep vein thrombosis and smoking were less likely to heal.

What are the most effective wound care measures for diabetic foot ulcers?

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jillian Trieff Waller ◽  
Karen Borchert
Keyword(s):  
Diabetic Foot ◽  
Wound Care ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

scholarly journals Low Level Laser Therapy for the Treatment of Diabetic Foot Ulcers: A Critical Survey

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Kathrin H. Beckmann ◽  
Gesa Meyer-Hamme ◽  
Sven Schröder
Keyword(s):  
Clinical Trials ◽  
Laser Therapy ◽  
Diabetic Foot ◽  
Animal Studies ◽  
Wound Care ◽  
Low Level Laser Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Low Level Laser ◽  
Level Laser

Diabetic foot ulcers as one of the most common complications of diabetes mellitus are defined as nonhealing or long-lasting chronic skin ulcers in diabetic patients. Multidisciplinary care for the diabetic foot is common, but treatment results are often unsatisfactory. Low level laser therapy (LLLT) on wound areas as well as on acupuncture points, as a noninvasive, pain-free method with minor side effects, has been considered as a possible treatment option for the diabetic foot syndrome. A systematic literature review identified 1764 articles on this topic. Finally, we adopted 22 eligible references; 8 of them were cell studies, 6 were animal studies, and 8 were clinical trials. Cell studies and animal studies gave evidence of cellular migration, viability, and proliferation of fibroblast cells, quicker reepithelization and reformed connective tissue, enhancement of microcirculation, and anti-inflammatory effects by inhibition of prostaglandine, interleukin, and cytokine as well as direct antibacterial effects by induction of reactive oxygen species (ROS). The transferral of these data into clinical medicine is under debate. The majority of clinical studies show a potential benefit of LLLT in wound healing of diabetic ulcers. But there are a lot of aspects in these studies limiting final evidence about the actual output of this kind of treatment method. In summary, all studies give enough evidence to continue research on laser therapy for diabetic ulcers, but clinical trials using human models do not provide sufficient evidence to establish the usefulness of LLLT as an effective tool in wound care regimes at present. Further well designed research trials are required to determine the true value of LLLT in routine wound care.

scholarly journals Outcomes Following Advanced Wound Care for Diabetic Foot Ulcers: A Canadian Study

2017 ◽  
Vol 41 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Ivana Roth-Albin ◽  
Safiah H.C. Mai ◽  
Zeeshan Ahmed ◽  
Ji Cheng ◽  
Karen Choong ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Wound Care ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Canadian Study

scholarly journals Combination Therapy Revives Hope for Patients with Diabetic Foot Ulcer: A Case Report

2021 ◽  
Author(s):  
Naser Parizad ◽  
Kazem Hajimohammadi ◽  
Rasoul Goli
Keyword(s):  
Case Report ◽  
Combination Therapy ◽  
Diabetic Foot ◽  
Wound Care ◽  
Stable Condition ◽  
Foot Ulcer ◽  
Wound Management ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Present Case Report

Abstract BackgroundDiabetic foot ulcers, as one of the most debilitating complications of diabetes, can lead to amputation. Treatment and management of diabetic foot ulcers are among the most critical challenges for the patients and their families. Case presentationThe present case report is of a 63-year-old man with a 5-year history of uncontrolled type 2 diabetes who has had diabetic foot ulcers for the past three years on three sites of the left external ankle in the form of two deep circular ulcers with sizes of 6×4 cm and 6×8 cm, the sole as a superficial ulcer with a size of 6×3 cm, and the left heel as a deep skin groove. Moreover, the left hallux was completely gangrenous. The patient's ulcers were infected with Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa. Despite antibiotic therapy and routine dressing changes, the patient showed no improvement during the hospital stay. Accordingly, the patient was transferred to our service after consulting with the wound management team. Diabetic foot ulcers were treated and managed using a combination of maggot therapy, the Negative Pressure Wound Therapy (NPWT), and silver foam dressing. After three months and ten days, the patient's ulcers completely healed, and he was discharged from our service with the excellent and stable condition. ConclusionsBased on the present case report study's clinical results, wound-care teams can use the combination therapy applied in this study to treat refractory diabetic foot ulcers.

scholarly journals MANAJEMEN ULKUS KAKI DIABETIKUM : EFEKTIFITAS FOOT EXERCISE TERHADAP RISIKO DFU (DIABETIC FOOT ULCERS) PASIEN DIABETES MELLITUS DI AL HIJRAH WOUND CARE CENTER

2019 ◽  
Vol 14 (2) ◽  
pp. 95-101
Author(s):  
Fahruddin Kurdi ◽  
Ratna Puji Priyanti
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Wound Care ◽  
Care Center ◽  
Foot Ulcers ◽  
P Value ◽  
Diabetic Foot Ulcers ◽  
Post Test ◽  
Diabetic Foot Screening ◽  
Diabetes Melitus

ABSTRAK Jumlah penderita DM (diabetes melitus) saat ini semakin meningkat. Salah satu komplikasi yang terjadi yaitu DFU (diabetic foot ulcers). Banyak cara yang dapat dilakukan untuk mencegah DFU, salah satunya dengan diabetic foot exercise. Penelitian ini bertujuan untuk mengetahui efektifitas diabetic foot exercise terhadap risiko dfu (diabetic foot ulcers) pasien diabetes mellitus. Penelitian menggunakan design pre-eksperimen dengan pendekatan one-group pra-post test design. Populasi penderita diabetes yang berjumlah 60 orang, besar sampel 40 orang yang diambil menggunakan teknik purposive sampling. Resiko DFU dinilai menggunakan inlow’s 60-second diabetic foot screening tool dengan metode observasi. Analisa data menggunakan uji statistik Wilcoxon. Hasil penelitian ini didapatkan bahwa sebelum dilakukan diabetic foot exercise sebagian besar reponden mempunyai risiko sedang sebanyak 30 orang (75%), sesudah dilakukan diabetic foot exercise diperoleh bahwa sebagian besar responden risiko rendah sebanyak 32 orang (80%). Uji statistik Wilcoxon diperoleh nilai p value = 0,001 dimana nilai p value<α (0,05) yang berarti ada pengaruh diabetic foot exercise terhadap risiko diabetic foot ulcers. Diabetes foot exercise sangat efektif untuk penderita diabetes dalam mencegah risiko DFU. Penderita diabetes dapat melakukan diabetic foot exercise 2 kali dalam seminggu secara teratur.  Kata Kunci : Diabetes mellitus, Diabetic foot ulcers, diabetic foot exercise

scholarly journals Allogeneic Skin Substitutes Versus Human Placental Membrane Products in the Management of Diabetic Foot Ulcers: A Narrative Comparative Evaluation of the Literature

2019 ◽  
Vol 18 (1) ◽  
pp. 10-22 ◽  
Author(s):  
Joshua Luck ◽  
Timo Rodi ◽  
Alexander Geierlehner ◽  
Afshin Mosahebi
Keyword(s):  
Diabetic Foot ◽  
Wound Care ◽  
Controlled Trial ◽  
Intervention Group ◽  
Primary Outcome Measure ◽  
Secondary Outcome ◽  
Foot Ulcers ◽  
Skin Substitute ◽  
Diabetic Foot Ulcers ◽  
Skin Substitutes

Outcomes following standard wound care (SWC) for diabetic foot ulcers (DFUs) remain suboptimal. Supplementing SWC with tissue engineered allogeneic cellular wound therapies represents an emerging treatment strategy. This review aimed to evaluate the efficacy and safety of allogeneic skin substitutes and human placental membrane allografts in the management of DFUs. Ovid MEDLINE and Embase databases were searched from inception to October 2017. Any randomized controlled trial (RCT) with an allogeneic skin substitute or placental membrane allograft intervention group was included. Our primary outcome measure was the proportion of completely healed ulcers. Secondary outcome measures included time to complete wound healing and local adverse event rates. Each study was assessed for risk of bias and the quality of evidence was appraised using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach. Moderate quality evidence from 11 included RCTs demonstrated that both allogeneic cellular approaches improve the proportion of completely healed ulcers at 6 and 12 weeks. One RCT showed that a placental membrane allograft was superior to an allogeneic skin substitute, although this has yet to be repeated in other studies. The addition of allogeneic cellular wound products to SWC improves DFU outcomes. Further studies are required to conclusively establish if placental membrane allografts are superior to allogeneic skin substitutes.

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