Methicillin-resistant Staphylococcus aureus sterile-site infection: The importance of appropriate initial antimicrobial treatment*

2006 ◽  
Vol 34 (8) ◽  
pp. 2069-2074 ◽  
Author(s):  
Garrett E. Schramm ◽  
Jennifer A. Johnson ◽  
Joshua A. Doherty ◽  
Scott T. Micek ◽  
Marin H. Kollef
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antimicrobial Treatment ◽  
Site Infection ◽  
Methicillin Resistant ◽  
Sterile Site

scholarly journals MRSA – ‘Bug-Bear’ of a Surgical Practice: Reducing the Incidence of MRSA Surgical Site Infections

2006 ◽  
Vol 88 (2) ◽  
pp. 222-223 ◽  
Author(s):  
Andrea Guyot ◽  
Graham Layer
Keyword(s):  
Staphylococcus Aureus ◽  
Surgical Site Infection ◽  
Orthopaedic Surgery ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Surgical Site Infections ◽  
Site Infection ◽  
Infection Rates ◽  
Methicillin Resistant ◽  
Surgical Practice ◽  
Department Of Health

Adverse publicity (the ‘superbug') has demonstrated that the problem of MRSA (methicillin-resistant Staphylococcus aureus) is prevalent in many of the country's most prestigious hospitals. The results of the mandatory UK Department of Health (DH) surveillance for early surgical site infections in orthopaedic surgery (SSIS) have been published recently for the period April 2004 to March 2005 when 41,242 operations were studied (< http://www.dh.gov.uk/PublicationsAndStatistics/Publications/PublicationsStatistic > 28 October 2005). Infection rates were generally and gratifyingly low but 48% of surgical site infections were caused by Staph. aureus and of those 68% were MRSA. The following article will discuss the aetiology and prevention of MRSA surgical site infection.

Importance of Methicillin-Resistant Staphylococcus aureus Eradication in Carriers to Prevent Postoperative Methicillin-Resistant Staphylococcus aureus Surgical Site Infection

2011 ◽  
Vol 77 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Walter E. Pofahl ◽  
Keith M. Ramsey ◽  
Delores L. Nobles ◽  
M. Kathy Cochran ◽  
Claudia Goettler
Keyword(s):  
Staphylococcus Aureus ◽  
Surgical Site Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Tertiary Care ◽  
Carrier State ◽  
Care Hospital ◽  
Site Infection ◽  
Improvement Project ◽  
Methicillin Resistant ◽  
Rapid Polymerase Chain Reaction

Although infrequent, postoperative methicillin-resistant Staphylococcus aureus (MRSA) surgical site infection (SSI) is associated with significant morbidity and cost. Previous studies have identified the importance of MRSA screening to diminish the risk of postoperative MRSA SSI. The current study quantifies the importance of eradication of the MRSA carrier state to prevent MRSA SSI. Beginning February 2007, all admissions to an 800-bed tertiary care hospital were screened for MRSA by nasal swab using rapid polymerase chain reaction-based testing. Patients found to be nasal carriers of MRSA were treated with 2 per cent mupirocin nasal ointment and 4 per cent chlorhexidine soap before surgery. The subset of patients undergoing procedures that are part of the Surgical Care Improvement Project (SCIP) were followed for MRSA SSI (n = 8980). The results of preoperative MRSA screening and eradication of the carrier state were analyzed. Since the initiation of universal MRSA screening, 11 patients undergoing SCIP procedures have developed MRSA SSI (0.12%). Of these, six patients (55%) had negative preoperative screens. Of the five patients with positive preoperative screens, only one received treatment to eradicate the carrier state. In patients who develop MRSA SSI, failure to treat the carrier state before surgery results in MRSA SSI.

Endogenous methicillin resistant staphylococcus aureus as a source of post operative surgical site infections

2020 ◽  
pp. 1-12
Author(s):  
Umme Farwa ◽  
Irum Aftab ◽  
Fatima Kaleem ◽  
Mehnaz Khattak ◽  
Mariam Danish Iqbal ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Empirical Therapy ◽  
Surgical Site Infections ◽  
Sampling Technique ◽  
Site Infection ◽  
Cross Sectional ◽  
Methicillin Resistant ◽  
Time Of Admission

Abstract Objectives: To determine frequency of Endogenous Methicillin Resistant Staphylococcus aureus (MRSA) in pre operative patients and its frequency in Surgical Site Infections (SSIs) Post operatively. Methods: It was a descriptive cross sectional conducted at Department of Microbiology, Fauji Foundation Hospital Rawalpindi (FFH), Pakistan. Samples were collected from 1st November-31st May 2018. Total 75 samples were collected during the period. Consecutive non-probability sampling technique was utilized. Specimens were collected from nose, axilla and groin of preoperative patients. Methicillin Resistant Staphylococcus aureus was identified if only isolated from these sites. Patients were followed till his/her discharge from the hospital and if they developed infection post operatively, pus specimen from infected site was also collected and identified.Results: Out of 75 specimen preoperatively, 14.7% (n=11) were identified as endogenous MRSA. From these, 44% (n=33) developed Surgical site infections (SSIs), among them 57% (n=19) were MRSA (09 endogenous, 10 exogenous), 21.2% (n=7) were Escherichia coli, 9.1% (n=3) were Klebsiella pneumoniae, 9.1% (n=3) were Enterococcus faecalis and 3% (n=1) was Methicillin Sensitive Staphylococcus aureus. Conclusion:  The results of this study determined that Endogenous Methicillin Resistant Staphylococcus aureus (MRSA) could be isolated from patients going for surgery if microbiological screening was done at the time of admission. This could prevent patients from Surgical Site Infection Post operatively by these endogenous MRSA. This search and wipe out strategy is able to curtail the events of outbreak, reduce hospital stay and decrease budget of the hospital by providing guidance in choice of empirical therapy for infection. Continuous...

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