Long-term risk of diabetes, hypertension and left ventricular hypertrophy associated with the metabolic syndrome in a general population

2008 ◽  
Vol 26 (8) ◽  
pp. 1602-1611 ◽  
Author(s):  
Giuseppe Mancia ◽  
Michele Bombelli ◽  
Rita Facchetti ◽  
Fabiana Madotto ◽  
Giovanni Corrao ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
General Population ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
The Metabolic Syndrome

scholarly journals Left ventricular hypertrophy and linked cardiovascular risk factors among Congolese licensed civilian aircrew

2020 ◽  
Vol 5 (2) ◽  
pp. 28
Author(s):  
Nathan B Buila ◽  
Georges N Ngoyi ◽  
Yves N Lubenga ◽  
Jean-Marc B Bantu ◽  
Trésor S Mvunzi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Left Ventricular Hypertrophy ◽  
Cardiovascular Risk Factors ◽  
Ventricular Hypertrophy ◽  
Biological Evaluation ◽  
Left Ventricular ◽  
Flight Crew ◽  
The Metabolic Syndrome

Objective: To assess the prevalence of left ventricular hypertrophy (LVH) and linked cardiovascular risk factors in civilian aircrew.Methods: Cardiovascular risk factors were assessed among flight and cabin crew undergoing routine clinical and biological evaluation for initial or renewal of aeromedical license. The evaluation also included a standard 12-lead ECG and echocardiography. Echo-based LVH was LVM ≥ 49 g/m2.7 (men) or ≥ 45 g/m2.7 (women). LVH was categorized as mild (men: 49-55 g/m2.7; women: 45-51 g/m2.7), moderate (men: 56-63 g/m2.7; women: 52-58 g/m2.7), or severe (men: ≥ 64 g/m2.7; women: ≥ 59g/m2.7) according to Lang’s report.Results: Among the 379 aircrew members (70.4% men; 23% Caucasians; 62.5% flight crew; mean age 40.6 ± 12.8 years), LVH was present in 36 individuals (9.5%) with mild, moderate and severe pattern observed respectively in 19.4%, 33.3% and 47.2% of the cases. The rate of LVH amounted to 16.7% in normotensive subjects, 25.0% in those with prehypertension, and 58.3% among hypertensive individuals. In addition to age of 40-59y (OR: 8.48; 95% CI: [2.23-12.23]; p = .002) or more (4.22 [1.57-11.35]; p = .004), hypertension (3.55 [1.50 - 8.41]; p = .004), overweight/obesity (5.33 [1.14 - 25.05]; p = .034) and hyperuricemia (5.05 [2.11 - 12.09]; p = .001), all well-known constituents of the metabolic syndrome, were the main factors significantly associated with LVH.Conclusion: The frequency and link of LVH to the components of the metabolic syndrome highlights the need for a comprehensive approach to the management of cardiovascular risk factors in civilian aircrew.

scholarly journals The Metabolic Syndrome and ECG Detected Left Ventricular Hypertrophy – Influences from IGF-1 and IGF-Binding Protein-1

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e108872 ◽  
Author(s):  
Mats Halldin ◽  
Kerstin Brismar ◽  
Per Fahlstadius ◽  
Max Vikström ◽  
Ulf de Faire ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Binding Protein ◽  
Left Ventricular ◽  
The Metabolic Syndrome ◽  
Igf Binding ◽  
Igf Binding Protein

The metabolic syndrome and left ventricular hypertrophy – the influence of gender and physical activity

2011 ◽  
Vol 21 (3) ◽  
pp. 153-160 ◽  
Author(s):  
Mats Halldin ◽  
Per Fahlstadius ◽  
Ulf de Faire ◽  
Max Vikström ◽  
Mai-Lis Hellénius
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
The Metabolic Syndrome

scholarly journals Electrocardiographic Abnormalities and Mortality in Epilepsy Patients

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 504
Author(s):  
Normunds Suna ◽  
Inga Suna ◽  
Evija Gutmane ◽  
Linda Kande ◽  
Guntis Karelis ◽  
...  
Keyword(s):  
Heart Rate ◽  
General Population ◽  
Left Ventricular Hypertrophy ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Mortality Data ◽  
Qtc Interval ◽  
Study Objective

Background and Objectives: People with epilepsy (PWE) have a 2–3 times higher mortality rate than the general population. Sudden unexpected death in epilepsy (SUDEP) comprises a significant proportion of premature deaths, whereas sudden cardiac death (SCD) is among the leading causes of sudden death in the general population. Cardiac pathologies are significantly more prevalent in PWE. Whether electrocardiographic (ECG) parameters are associated with remote death in PWE has yet to be elucidated. The study objective was to assess whether interictal ECG parameters are associated with mortality in the long-term. Materials and Methods: The study involved 471 epilepsy patients who were hospitalized after a bilateral tonic-clonic seizure(s). ECG parameters were obtained on the day of hospitalization (heart rate, PQ interval, QRS complex, QT interval, heart rate corrected QT interval (QTc), ST segment and T wave changes), as well as reported ECG abnormalities. Mortality data were obtained from the Latvian National Cause-of-Death database 3–11, mean 7.0 years after hospitalization. The association between the ECG parameters and the long-term clinical outcome were examined. Results: At the time of assessment, 75.4% of patients were alive and 24.6% were deceased. Short QTc interval (odds ratio (OR) 4.780; 95% confidence interval (CI) 1.668–13.698; p = 0.004) was associated with a remote death. After the exclusion of known comorbidities with high mortality rates, short QTc (OR 4.631) and ECG signs of left ventricular hypertrophy (OR 5.009) were associated with a remote death. Conclusions: The association between routine 12-lead rest ECG parameters—short QTc interval and a pattern of left ventricular hypertrophy—and remote death in epilepsy patients was found. To the best of our knowledge, this is the first study to associate rest ECG parameters with remote death in an epileptic population.

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