scholarly journals Population genetic difference of pharmacogenomic VIP gene variants in the Lisu population from Yunnan Province

Medicine ◽  
2018 ◽  
Vol 97 (52) ◽  
pp. e13674 ◽  
Author(s):  
Chan Zhang ◽  
Xiaochun Jiang ◽  
Wanlu Chen ◽  
Qi Li ◽  
Fubin Yun ◽  
...  
Genetika ◽  
2015 ◽  
Vol 47 (2) ◽  
pp. 451-468 ◽  
Author(s):  
Malahat Taban ◽  
Masoud Sheidai ◽  
Zahra Noormohammadi ◽  
Narjes Azizi ◽  
Somayeh Ghasemzadeh-Baraki ◽  
...  

Helichrysum armenium and H. rubicundum are two medicinally important plants of Iran that are distributed in various regions of the country. They are extensively used by locals as medicinal plants and a great negative selection pressure is applied on them. Therefore, due to importance of these plant species, we performed a population genetic study in both species. For this study, we used 66 randomly collected plants from 24 geographical populations of Helichrysum armenium and H. rubicundu. These species had areas of overlap and contact and we found some intermediate plants that were included in our study too. UPGMA and MDS analyses revealed morphological separation of these closely related species and placed intermediate plants in an intermediate position. ISSR analysis revealed inter-population genetic diversity and K-Means clustering and STRUCTURE analyses revealed populations. Genetic stratification in both species. Genetic difference of the studied populations was not correlated to geographical distance. Triangle plot of Bayesian analysis and NeighborNet plot showed inter-specific gene flow. The studied populations showed plants with 2n = 2x = 14 and 2n = 4x = 28 chromosomes and differed significantly in their meiotic behavior. Therefore, a combination of genetic stratification, and genetic admixture as well as polyploidy and chromosomes structural changes, have played rule in Helichrysum diversification.


2021 ◽  
Vol Volume 14 ◽  
pp. 1027-1040
Author(s):  
Chunjuan He ◽  
Linna Peng ◽  
Shishi Xing ◽  
Dandan Li ◽  
Li Wang ◽  
...  

2020 ◽  
Vol 8 (2) ◽  
pp. 145
Author(s):  
Agus Nuryanto ◽  
Dian Baghawati ◽  
Kusbiyanto Kusbiyanto ◽  
Moh Husein Sastranegara ◽  
Farida Nur Rachmawati

The taxonomic status of Anguilla species' in river watershed that empties into Segara Anakan Cilacap is uncertain, thereby making it difficult for further studies to be carried out to determine its genetic in that area. Therefore, this study evaluates Anguilla's taxonomic status and population genetic in Cibeureum and Sapuregel River watersheds. Data were obtained from molecular characterization study using cytochrome c oxidase 1, with fourteen Anguilla specimens collected from two sequenced watersheds. Taxonomic status was determined based on homology and divergence values and monophyly of the samples to the reference species. Meanwhile, genetic divergences among samples to the reference species were calculated based on the Juke-Cantor substitution model in DnaSP6. A homology test was performed using a basic local alignment search tool, with monophyly inferred from the cladogram, which was developed using neighbor-joining and maximum likelihood algorithms in MEGAX with 1000 pseudoreplicates and out-group comparison. Furthermore, population genetic was analyzed through polymorphism, haplotype, nucleotide diversity within the population, divergence, and genetic differences. All calculations conducted in Arlequin 3.5 had Anguilla samples comprising of high (99.23% to 99.84%) to low genetic divergences (0.224% to 1.127%). The result shows that cladogram with all Anguilla samples formed a monophyletic clade with A. bicolor, separated from their taxa. Furthermore, Anguilla samples from both watersheds have low genetic polymorphisms with medium to high haplotype and nucleotide diversity. The population's comparison proved that both populations have low genetic divergence, and no genetic difference based on variance analysis (p=0761). Therefore, Anguilla resources in river watersheds that empty into Segara Anakan are a single genetic conservation unit.


Genetika ◽  
2016 ◽  
Vol 48 (2) ◽  
pp. 497-514 ◽  
Author(s):  
Masoud Sheidai ◽  
Mona Naji ◽  
Zahra Noormohammadi ◽  
Maryam Nouroozi ◽  
Somayeh Ghasemzadeh-Baraki

Cirsium aduncum Fisch. & C.A.Mey. Ex DC. and C. haussknechtii Boiss., (Asteraceae) are important medicinal plant species that grow in different geographical regions of Iran. We had no knowledge about population genetic structure, intra-specific and inter-specific gene flow and the presence of hybrid zone for this two species in Iran. Therefore, in order to provide data for conservation of these two medicinally important species, the population genetic analysis and morphometric studies were performed in 18 geographical populations of these species. ANOVA and MDS analyses revealed significant morphological difference among the studied populations in either species, while MDS plot showed morphological overlap in plants of these two species. AMOVA test revealed significant genetic difference among the studied populations. Mantel test showed positive significant correlation between genetic and geographical distances and the occurrence of isolation by distance. Population assignment test and STRUCTURE plot of genetic data revealed inter-specific introgression between these species.


2021 ◽  
Vol 28 (1) ◽  
pp. 61-73
Author(s):  
Xi Fei ◽  
Ruan Xuejun ◽  
Amir Abbas Minaeifar

Erodium ciconium is an important grazing plant and a source of protein supplements to straw for ruminants in semideserts and wastelands of the Middle East. There is no information on its population genetic structure, genetic diversity, and morphological variability in Iran. We performed molecular data for knowing the population differentiation in this species. For this study, we used 110 randomly collected plants from 15 geographical populations in 6 provinces of Iran. AMOVA test revealed significant genetic difference among the studied populations and also revealed that, 63% of total genetic variability was due to within population diversity while, 37% was due to among population genetic differentiation. Mantel test showed positive significant correlation between genetic distance and geographical distance of the studied populations. Networking, STRUCTURE analyses revealed some degree of gene flow among these populations. Bangladesh J. Plant Taxon. 28(1): 61-73, 2021 (June)


PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e64150 ◽  
Author(s):  
Yongshuai Jiang ◽  
Ruijie Zhang ◽  
Hongchao Lv ◽  
Jin Li ◽  
Miao Wang ◽  
...  

Genetika ◽  
2021 ◽  
Vol 53 (2) ◽  
pp. 867-882
Author(s):  
Liu Hang ◽  
Li Pan ◽  
Tang Yong ◽  
Luo Jianguo ◽  
Xu Xingmin ◽  
...  

The genus Alcea, a member of Malvaceae family consists of approximately 75 species worldwide distributing mainly in South-West Asia. Among these, 33 species grow in Iran. Plants of the Alcea (or Althaea) are among important medicinal plants in Iranian traditional medicine. They have long been used in the treatment of health problems and diseases. Alcea aucheri (Boiss.) Alef. species are distributed in different habitats of Iran. There is no information on its population genetic structure, genetic diversity, and morphological variability in Iran. Therefore, due to the importance of these plant species, we performed a combination of morphological and molecular data for this species. For this study, we used 118 randomly collected plants from 10 geographical populations in 5 provinces. AMOVA test revealed significant genetic difference among the studied populations and also revealed that, 74% of total genetic variability was due to within population diversity while, 26% was due to among population genetic differentiation. Mantel test showed positive significant correlation between genetic distance and geographical distance of the studied populations. Networking, STRUCTURE analyses revealed some degree of gene flow among these populations.


2020 ◽  
Vol 63 (2) ◽  
pp. 269-275
Author(s):  
Koray Kirikci ◽  
M. Akif Cam ◽  
Levent Mercan

Abstract. The Karayaka is the most populous sheep breed in the Black Sea region of Turkey. In the present study, we investigated the intra- and inter-population genetic relationships among indigenous Karayaka sheep subpopulations. Nine microsatellites were genotyped for 64 individuals from Samsun, Ordu, Giresun and Tokat provinces. The average number of alleles (Na), allelic richness (Ar), observed heterozygosity (Ho), expected heterozygosity (He), polymorphism information content (PIC) and inbreeding coefficient (FIS) for all subpopulations were estimated as Na=16.44, Ar=9.887, Ho=0.303, He=0.886, PIC=0.866 and FIS=0.630, respectively. The observed and expected heterozygosity ranged from 0.171 (Giresun) to 0.376 (Ordu) and 0.757 (Samsun) to 0.845 (Ordu), respectively. It was determined that a 10.5 % of total genetic variation (FIT=66.9 %) in Karayaka sheep corresponded to genetic differences among subpopulations (FST), whereas 63.0 % was explained by genetic difference among individuals (FIS). This study gives the first evidence about genetic relationships of Karayaka subpopulations. The results show that Karayaka sheep subpopulations are genetically different from each other. These findings revealed that the Karayaka breed has discrete subpopulations and should be taken into consideration when preparing conservation programs and future breeding strategies.


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