scholarly journals Successful treatment with lorlatinib in a patient with meningeal carcinomatosis of ALK-positive non-small cell lung cancer resistant to alectinib and brigatinib

Medicine ◽  
2021 ◽  
Vol 100 (39) ◽  
pp. e27385
Author(s):  
Koki Nakashima ◽  
Yoshiki Demura ◽  
Kosuke Kurokawa ◽  
Toshihiro Takeda ◽  
Norihiro Jikuya ◽  
...  
Lung Cancer ◽  
2015 ◽  
Vol 88 (1) ◽  
pp. 112-113 ◽  
Author(s):  
Tomonobu Koizumi ◽  
Toshirou Fukushima ◽  
Toshiharu Tatai ◽  
Takashi Kobayashi ◽  
Nodoka Sekiguchi ◽  
...  

2021 ◽  
Vol 16 (4) ◽  
pp. S782
Author(s):  
I. Dogan ◽  
M. Gürbüz ◽  
N. Paksoy ◽  
F. Ferhatoğlu ◽  
S. Vatansever ◽  
...  

2020 ◽  
Vol 26 (8) ◽  
pp. 2031-2033
Author(s):  
Nilay Sengul Samanci ◽  
Emir Celik ◽  
Burak Akovalı ◽  
Sait Sager ◽  
Fuat Hulusi Demirelli

Introduction Ceritinib is a selective second-generation ALK inhibitor that is highly sensitive to echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) molecule. Case report In this paper, we report a 68-year-old female that was diagnosed with stage 4 ALK-positive non-small cell lung cancer (NSCLC). Management and outcome: She was treated with crizotinib first-line, cisplatin and gemcitabine as second-line. And for third-line, ceritinib was started. She had complete response over 3.5 years under ceritinib treatment. And she is still receiving ceritinib with no adverse event. Discussion Cases achieving complete response with ceritinib treatment are rare. In this paper, we aimed to emphasize the complete response in stage 4 NSCLC in an elderly patient.


2013 ◽  
Vol 8 (12) ◽  
pp. 1570-1573 ◽  
Author(s):  
Justin F. Gainor ◽  
Sai-Hong Ignatius Ou ◽  
Jennifer Logan ◽  
Lawrence F. Borges ◽  
Alice T. Shaw

2017 ◽  
Vol 12 (1) ◽  
pp. S378-S379 ◽  
Author(s):  
Young Kim ◽  
Toyoaki Hida ◽  
Hiroshi Nokihara ◽  
Masashi Kondo ◽  
Koichi Azuma ◽  
...  

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