Prevalence and Associated Risk Factors of Pulmonary Embolism in Children and Young Adults With Nephrotic Syndrome

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Haitao Zhu ◽  
Jianchen Qi ◽  
Joseph Schoepf ◽  
Rock H. Savage ◽  
Chunxiang Tang ◽  
...  
2011 ◽  
Vol 70 (5) ◽  
pp. 713-721 ◽  
Author(s):  
Mary G. George ◽  
Xin Tong ◽  
Elena V. Kuklina ◽  
Darwin R. Labarthe

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Tohshin Go

Purpose. Adjunctive zonisamide therapy was demonstrated to be beneficial for multiple-disabled patients with refractory childhood-onset epilepsy. Zonisamide is well tolerated, but urolithiasis and calcium sludge in the bladder were sometimes described in patients treated with antiepileptic drug polytherapy including zonisamide. In previous studies, alkaline urine and crystalluria were shown to be risk factors for urolithiasis. Therefore, the effects of zonisamide addition and withdrawal on the urinary pH and crystalluria were investigated in patients treated with antiepileptic drug polytherapy to clarify the cause of urolithiasis induced by zonisamide. Methods. The urinary pH and the degree of crystalluria were retrospectively studied in epilepsy patients one month after the addition or withdrawal of zonisamide as part of their antiepileptic drug treatment regimen over the previous three years. Results. A total of 27 zonisamide-on patients and 16 zonisamide-off patients were enrolled in the study. The urinary pH did not change after the addition or withdrawal of zonisamide. However, the degree of crystalluria significantly increased after the addition () of zonisamide and decreased after its withdrawal (). Conclusions. Zonisamide induces crystalluria without alkalinization of the urine. Crystalluria should be carefully monitored in patients treated with zonisamide to prevent urolithiasis.


2019 ◽  
Vol 243 ◽  
pp. 173-179 ◽  
Author(s):  
Kerri McKie ◽  
Robert J. McLoughlin ◽  
Michael P. Hirsh ◽  
Muriel A. Cleary ◽  
Jeremy T. Aidlen

2019 ◽  
Vol 27 (1) ◽  
Author(s):  
Amber M Beynon ◽  
Jeffrey J Hebert ◽  
Charlotte Lebouef-Yde ◽  
Bruce F Walker

Abstract Background The one-month prevalence of back pain in children and adolescents has been reported at 33, 28 and 48% at ages 9, 13 and 15 respectively. There are many suspected risk factors and triggers of back pain in young people. Objective The purpose of this scoping review was to identify potential risk factors and potential triggers for back pain in young people. The purpose of part I was to identify potential risk factors for incident and episodic back pain in young people. Part II included all eligible studies with unclear or mixed types of back pain. Methods Due to the vast number of studies on “risk factors” for back pain, a two-part scoping review of the literature was chosen as the best way to summarise the evidence. We adhered to the PRISMA-ScR guideline for scoping reviews. General potential risk factors and triggers for back pain in children and young adults (≤ 24 years) were included, incorporating physical, environmental, and/or physiological factors. A search was conducted using PubMed and Cochrane databases from inception to September 2018, limited to the English language. Within part I, and because of their importance, only the results of the studies that investigated risk factors of incident back pain and back pain episodes are presented. Results The search identified 7356 articles, of which 91 articles were eligible for this scoping review. The majority of the eligible articles had an unclear definition of back pain (results presented in scoping review part II). There were 7 inception cohort studies included and 1 cohort study that met the criteria for part I. The most consistent risk factors for incident and episodic back pain are female sex and older age. Conclusion Due to inconsistent ways of reporting on the type of back pain, no definitive risk factor for back pain has been identified. In general, females often report more symptoms, also for other diseases, and older age is not a useful risk factor as it merely indicates that the onset may not be in childhood. Clearly, the time has come to study the causes of back pain from different angles.


PEDIATRICS ◽  
2012 ◽  
Vol 129 (6) ◽  
pp. e1552-e1561 ◽  
Author(s):  
E. F. Davis ◽  
M. Lazdam ◽  
A. J. Lewandowski ◽  
S. A. Worton ◽  
B. Kelly ◽  
...  

2011 ◽  
Vol 88 (8) ◽  
pp. 973-980 ◽  
Author(s):  
Heidi Wagner ◽  
Robin L. Chalmers ◽  
G. Lynn Mitchell ◽  
Meredith E. Jansen ◽  
Beth T. Kinoshita ◽  
...  

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