Evaluation of Nasal Mucociliary Clearance Time in COVID-19 Patients

AbstractObjectiveThis study aimed to examine nasal mucociliary clearance time in patients with Helicobacter pylori infection.MethodsFifty patients who were newly diagnosed with H pylori infection using gastric biopsy in the gastroenterology out-patient clinic, and 50 age- and gender-matched healthy adults who were admitted to the otorhinolaryngology out-patient clinic, were included in this study. After an otorhinolaryngological examination (anterior rhinoscopy and nasal endoscopic examination), the nasal mucociliary clearance time of each subject was calculated using the saccharine test.ResultsThe mean mucociliary clearance time was 06:29 ± 3:31 minutes (range, 00:55–15:19 minutes) in the control group and 10:12 ± 06:09 minutes (range, 01:28–32:00 minutes) in the study group. Comparisons of the two groups revealed a statistically significant difference (p = 0.002).ConclusionNasal mucociliary clearance time was significantly increased in patients with H pylori infection. The results suggest that H pylori infection may have an unfavourable effect on nasal mucociliary clearance.

Download Full-text

Air Pollution and Nasal Mucociliary Clearance Time among Urban and Rural Residents in Two Philippine Communities

Philippine Journal of Otolaryngology Head and Neck Surgery ◽

10.32412/pjohns.v35i1.1275 ◽

2020 ◽

Vol 35 (1) ◽

pp. 33-35

Author(s):

Soraya Joson ◽

Joman Laxamana

Keyword(s):

Air Pollution ◽

Methylene Blue ◽

Air Quality ◽

Quality Index ◽

Mucociliary Clearance ◽

Air Quality Index ◽

Clearance Time ◽

Rural Residents ◽

Air Index ◽

Nasal Mucociliary Clearance

ABSTRACT Objective: To measure the nasal mucociliary clearance (NMC) time among adults residing in two Philippine communities with different air quality indices using the saccharin and methylene blue test. Methods: Design: Cross-Sectional Study Setting: Diliman, Quezon City and Puerto Princesa, Palawan Participantss: Fifty (50) participants, 25 residing in an urban city with fair air quality index and 25 residing in a rural province with good air quality index. Results: The mean NMC time of the urban group was 22.15±12.68 mins and was significantly longer than the NMC time of the rural group which was 5.29±2.87mins; t(48) = 6.643, p<0.0001). Conclusion: Increased air pollution may be associated with significant prolongation of nasal mucociliary clearance time among urban residents with fair quality air index compared to rural residents with good quality air index. Keywords: nasal mucociliary clearance, naso mucociliary clearance time, air pollution, air quality index, saccharin test, methylene blue

Download Full-text

Assessment of nasal mucociliary activity in patients with Behçet's disease

The Journal of Laryngology & Otology ◽

10.1017/s0022215116000207 ◽

2016 ◽

Vol 130 (4) ◽

pp. 348-351 ◽

Cited By ~ 3

Author(s):

I Ozbay ◽

C Kucur ◽

F Temİzturk ◽

Y Ozkan ◽

C Kahraman ◽

...

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Disease Duration ◽

Mucociliary Clearance ◽

Behçet's Disease ◽

International Study ◽

Clearance Time ◽

Behcet's Disease ◽

Control Subjects ◽

Nasal Mucociliary Clearance

AbstractObjective:To investigate nasal mucociliary clearance in patients with Behçet's disease.Methods:Thirty patients with Behçet's disease, diagnosed on the basis of criteria defined by the International Study Group for Behçet's Disease, and 30 healthy individuals were recruited. In both groups, individuals with conditions that could affect nasal mucociliary clearance were excluded. Nasal mucociliary clearance time was evaluated using saccharin tests. The time between placement of a saccharin tablet and the tasting of the saccharin was measured and recorded as the saccharin clearance time.Results:The mean nasal mucociliary clearance time was significantly longer in the Behçet's disease patients than in the control subjects (p < 0.001). Furthermore, there was a positive correlation between Behçet's disease duration and nasal mucociliary clearance time (p < 0.001, r = 0.882).Conclusion:The results suggest that nasal mucociliary clearance time is longer in Behçet's disease patients than in control subjects, and is positively correlated with disease duration.

Download Full-text

Anterior Rhinomanometry and Determination of Nasal Mucociliary Clearance Time With the Saccharin Test in Children With Crimean-Congo Hemorrhagic Fever

Journal of Craniofacial Surgery ◽

10.1097/scs.0b013e318286084a ◽

2013 ◽

Vol 24 (3) ◽

pp. e239-e242 ◽

Cited By ~ 2

Author(s):

Emine Elif Altuntaş ◽

Ali Kaya ◽

İsmail Önder Uysal ◽

Ömer Cevit ◽

Dilara İçağasioğlu ◽

...

Keyword(s):

Mucociliary Clearance ◽

Hemorrhagic Fever ◽

Clearance Time ◽

Crimean Congo Hemorrhagic Fever ◽

Nasal Mucociliary Clearance

Download Full-text

Nasal Mucociliary Clearance in Allergic Rhinitis in Children

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1035 ◽

2010 ◽

Vol 3 (2) ◽

pp. 93-95

Author(s):

Rupender K Ranga ◽

Jyoti Yadav ◽

Jagat Singh

Keyword(s):

Allergic Rhinitis ◽

Mucociliary Clearance ◽

Pulmonary Diseases ◽

Healthy Controls ◽

Clearance Time ◽

Uncommon Disease ◽

Significant Impairment ◽

Nasal Mucociliary Clearance ◽

Age And Sex

Abstract Allergic rhinitis in children is not an uncommon disease in India. Our objective was to evaluate the effect of allergic rhinitis on nasal mucociliary clearance. The nasal mucociliary clearance time (NMC) was studied using Andersen's saccharin method in fifty controls and fifty age and sex matched patients of allergic rhinitis. The nasal mucociliary clearance time in healthy controls was found to be 5.11 ± 1.51 minutes. A significant impairment (p < 0.01) in nasal mucociliary clearance time of 12.46 ± 3.74 minutes was observed in children suffering with allergic rhinitis, signifying that allergic rhinitis may predispose to sinusitis and pulmonary diseases.

Download Full-text

Evaluation of Nasal Mucociliary Clearance Time by Saccharin Test in Patients with Obstructive Sleep Apnea

Turkiye Klinikleri Archives of Lung ◽

10.5336/archlung.2018-60354 ◽

2018 ◽

Vol 19 (1) ◽

pp. 6-10

Author(s):

Seyhan DÜLGER ◽

Fevzi SOLMAZ

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Mucociliary Clearance ◽

Clearance Time ◽

Obstructive Sleep ◽

Nasal Mucociliary Clearance

Download Full-text

Mucociliary Function: Its Variations with Disease

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1271 ◽

2016 ◽

Vol 9 (2) ◽

pp. 68-73

Author(s):

Satish C Kumar ◽

AP Preetham ◽

Musarrat Feshan

Keyword(s):

Chronic Rhinosinusitis ◽

Clearance Rate ◽

Mucociliary Clearance ◽

Chronic Sinusitis ◽

Clearance Time ◽

Cigarette Smokers ◽

Mucociliary Function ◽

Nose And Paranasal Sinuses ◽

Nasal Mucociliary Clearance ◽

Nose And Throat

ABSTRACT Introduction This study compares the nasal mucociliary clearance time of patients with chronic sinusitis (pre- and postoperatively) and smokers, with controls, attending the ear, nose, and throat outpatient department at Southern Railway Headquarters Hospital, Perambur, Chennai. Materials and methods Saccharin granule was used to study mucociliary clearance as it is safe, easy, fast, and reliable. A total of 32 patients in each group were studied. In chronic rhinosinusitis patients, the test was done preoperatively and 4 weeks postoperatively. Results The average mucociliary clearance time pre- and post-operatively in chronic rhinosinusitis patients was 29.54 ± 28.68 and 12.17 ± 5.84 respectively. Cigarette smokers had a longer mucociliary clearance time (27.63 ± 21.11) compared with beedi smokers (24.04 ± 24.93). Controls had the fastest mucociliary clearance rate of 9.67 ± 4.62 among the study subjects. Conclusion Surgery for chronic rhinosinusitis improves both the overall symptoms of chronic rhinosinusitis and the protective functions of the nose and paranasal sinuses. Smokers had an impaired clearance rate compared with normals. As age advances, the mucociliary clearance rate becomes slower. How to cite this article Vamanshankar H, Kumar SC, Preetham AP, Feshan M. Mucociliary Function: Its Variations with Disease. Clin Rhinol An Int J 2016;9(2):68-73.

Download Full-text