scholarly journals Collective knowledge: organizing research projects as a database of reusable components and portable workflows with common interfaces

2021 ◽  
Vol 379 (2197) ◽  
Author(s):  
Grigori Fursin
Keyword(s):  
Evaluation Process ◽  
Research Projects ◽  
Collective Knowledge ◽  
Reusable Components ◽  
Knowledge Framework ◽  
Industrial Projects ◽  
Application Programming ◽  
Speed Accuracy ◽  
Programming Interfaces

This article provides the motivation and overview of the Collective Knowledge Framework (CK or cKnowledge). The CK concept is to decompose research projects into reusable components that encapsulate research artifacts and provide unified application programming interfaces (APIs), command-line interfaces (CLIs), meta descriptions and common automation actions for related artifacts. The CK framework is used to organize and manage research projects as a database of such components. Inspired by the USB ‘plug and play’ approach for hardware, CK also helps to assemble portable workflows that can automatically plug in compatible components from different users and vendors (models, datasets, frameworks, compilers, tools). Such workflows can build and run algorithms on different platforms and environments in a unified way using the customizable CK program pipeline with software detection plugins and the automatic installation of missing packages. This article presents a number of industrial projects in which the modular CK approach was successfully validated in order to automate benchmarking, auto-tuning and co-design of efficient software and hardware for machine learning and artificial intelligence in terms of speed, accuracy, energy, size and various costs. The CK framework also helped to automate the artifact evaluation process at several computer science conferences as well as to make it easier to reproduce, compare and reuse research techniques from published papers, deploy them in production, and automatically adapt them to continuously changing datasets, models and systems. The long-term goal is to accelerate innovation by connecting researchers and practitioners to share and reuse all their knowledge, best practices, artifacts, workflows and experimental results in a common, portable and reproducible format at cKnowledge.io . This article is part of the theme issue ‘Reliability and reproducibility in computational science: implementing verification, validation and uncertainty quantification in silico ’.

scholarly journals Remote control library and GUI development for Russian crawler robot Servosila Engineer

2018 ◽  
Vol 161 ◽  
pp. 03016 ◽  
Author(s):  
Ilya Mavrin ◽  
Roman Lavrenov ◽  
Mikhail Svinin ◽  
Sergey Sorokin ◽  
Evgeni Magid
Keyword(s):  
Graphical User Interface ◽  
Global Market ◽  
Research Projects ◽  
Urban Search And Rescue ◽  
Control Software ◽  
Robot System ◽  
High Quality ◽  
Ongoing Research ◽  
Application Programming ◽  
Programming Interfaces

Recently a large variety of robots are available on the global market for a reasonable price. Often it turns out that even though a robot has a high-quality hardware and architecture, an original software of the robot may have a number of drawbacks or lacks some important features, which are required for a particular application of the robot. In such cases a user may decide to implement new libraries and functionalities using a provided by a manufacturer application programming interfaces as in most cases code of a commercial robot system is not an open-source. A number of our ongoing research projects concentrate on applications of various robots in urban search and rescue operations, and in most of these projects utilize Russian crawler robot Servosila Engineer. This paper describes the development of a new ROS-based control software and graphical user interface for Servosila Engineer robot.

scholarly journals Deep Relations in Nordic and Baltic Biodiversity e-Infrastructures  (DeepDive)

2019 ◽  
Vol 3 ◽  
Author(s):  
Matthias Obst ◽  
Jesper Bladt ◽  
Frank Hanssen ◽  
Holger Dettki ◽  
Anders Telenius ◽  
...  
Keyword(s):  
Information Systems ◽  
User Interfaces ◽  
Data Services ◽  
Virtual Laboratories ◽  
Infrastructure Network ◽  
Application Programming ◽  
System Interoperability ◽  
Common Application ◽  
Programming Interfaces

The vision of the DeepDive program (https://neic.no/deepdive) is to establish a regional infrastructure network consisting of Nordic and Baltic data centers and information systems and to provide seamlessly operating regional data services, tools, and virtual laboratories. The program is funded by the Nordic e-Infrastructure Collaboration (https://neic.no) and was launched in 2017. Here we present some of the results and outcomes from the technical collaborations in the network. We will show examples of integration of biodiversity data services and portals though common Application Programming Interfaces (APIs) and Graphical User Interfaces (GUIs), describe our program to foster a biodiversity informatics community in the region, and explain advances in system interoperability that have been achieved over the past three years. We will also highlight the technical plans for further development and long-term sustainability of our Nordic and Baltic e-infrastructure network and make suggestions for further linkage to international information systems and ESFRI infrastructures.

Novel Targets For Therapeutic Intervention in Inflammatory Bowel Disease. What is the Best Way to Assess the Safety Profile of a Drug?

2019 ◽  
Vol 25 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Clara Yzet ◽  
Stacy S. Tse ◽  
Maia Kayal ◽  
Robert Hirten ◽  
Jean-Frédéric Colombel
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Evaluation Process ◽  
Population Based ◽  
Stage Of Development ◽  
Remission Rates ◽  
Safety Parameters ◽  
Post Marketing ◽  
Inflammatory Bowel

The emergence of biologic therapies has revolutionized the management of inflammatory bowel disease (IBD) by halting disease progression, increasing remission rates and improving long-term clinical outcomes. Despite these well-described benefits, many patients are reluctant to commence therapy due to drug safety concerns. Adverse events can be detected at each stage of drug development and during the post-marketing period. In this article, we review how to best assess the safety parameters of new IBD medications, from the earliest stage of development to population-based registries, with a focus on the special populations often excluded from the evaluation process.

The Geography of Insight

2018 ◽  
Author(s):  
Richard Foley
Keyword(s):  
Collective Knowledge ◽  
Key Features

This book, based on a philosopher’s experiences as dean over almost two decades, argues it is appropriate for the sciences and humanities to have different aims and for the values informing their inquiries also to be different. It maintains there are four core differences: (1) it is proper for the sciences but not the humanities to seek insights not limited to particular locations, times, or things; (2) the sciences but not the humanities value findings as independent as possible of the perspectives of the inquirers; (3) the sciences should be wholly descriptive while the humanities can also be concerned with prescriptive claims, which give expression to values; and (4) the sciences are organized to increase collective knowledge, whereas in the humanities individual insight is highly valued independently of its ability to generate consensus. Associated with these differences are secondary distinctions: different attitudes about an endpoint of inquiry; different notions of intellectual progress; different roles for expertise; different assumptions about simplicity and complexity; and different approaches to issues associated with consciousness. Taken together these distinctions constitute an intellectual geography of the humanities and sciences: a mapping of key features of their epistemology. In addition, the book discusses the role of universities in an era attached to sound bites and immediately useful results, and the importance of there being a healthy culture of research for both the sciences and humanities, one that treasures long-term intellectual achievements and whose presiding value is that with respect to many issues it ought not to be easy to have opinions.

scholarly journals Long-term risks after kidney donation: how do we inform potential donors? A survey from DESCARTES and EKITA transplantation working groups

2021 ◽  
Author(s):  
Geir Mjøen ◽  
Umberto Maggiore ◽  
Nicos Kessaris ◽  
Diederik Kimenai ◽  
Bruno Watschinger ◽  
...  
Keyword(s):  
Evaluation Process ◽  
Kidney Donation ◽  
Kidney Donors ◽  
Living Kidney Donors ◽  
Relative Risks ◽  
Written Information ◽  
The Difference ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background Publications from the last decade have increased knowledge regarding long-term risks after kidney donation. We wanted to perform a survey to assess how transplant professionals in Europe inform potential kidney donors regarding long-term risks. The objectives of the survey were to determine how they inform donors and to what extent, and to evaluate the degree of variation. Methods All transplant professionals involved in the evaluation process were considered eligible, regardless of the type of profession. The survey was dispatched as a link to a web-based survey. The subjects included questions on demographics, the information policy of the respondent and the use of risk calculators, including the difference of relative and absolute risks and how the respondents themselves understood these risks. Results The main finding was a large variation in how often different long-term risks were discussed with the potential donors, i.e. from always to never. Eighty percent of respondents stated that they always discuss the risk of end-stage renal disease, while 56% of respondents stated that they always discuss the risk of preeclampsia. Twenty percent of respondents answered correctly regarding the relationship between absolute and relative risks for rare outcomes. Conclusions The use of written information and checklists should be encouraged. This may improve standardization regarding the information provided to potential living kidney donors in Europe. There is a need for information and education among European transplant professionals regarding long-term risks after kidney donation and how to interpret and present these risks.

scholarly journals Chances and challenges of a long-term data repository in multiple sclerosis: 20th birthday of the German MS registry

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lisa-Marie Ohle ◽  
David Ellenberger ◽  
Peter Flachenecker ◽  
Tim Friede ◽  
Judith Haas ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Sociodemographic Factors ◽  
Healthcare Research ◽  
Structure Design ◽  
Data Repository ◽  
Research Projects ◽  
Real World Data ◽  
Data Repositories ◽  
Term Data

AbstractIn 2001, the German Multiple Sclerosis Society, facing lack of data, founded the German MS Registry (GMSR) as a long-term data repository for MS healthcare research. By the establishment of a network of participating neurological centres of different healthcare sectors across Germany, GMSR provides observational real-world data on long-term disease progression, sociodemographic factors, treatment and the healthcare status of people with MS. This paper aims to illustrate the framework of the GMSR. Structure, design and data quality processes as well as collaborations of the GMSR are presented. The registry’s dataset, status and results are discussed. As of 08 January 2021, 187 centres from different healthcare sectors participate in the GMSR. Following its infrastructure and dataset specification upgrades in 2014, more than 196,000 visits have been recorded relating to more than 33,000 persons with MS (PwMS). The GMSR enables monitoring of PwMS in Germany, supports scientific research projects, and collaborates with national and international MS data repositories and initiatives. With its recent pharmacovigilance extension, it aligns with EMA recommendations and helps to ensure early detection of therapy-related safety signals.

scholarly journals Addressing Semantics Standards for Cloud Portability and Interoperability in Multi Cloud Environment

Symmetry ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 317
Author(s):  
Chithambaramani Ramalingam ◽  
Prakash Mohan
Keyword(s):  
Service Providers ◽  
Research Work ◽  
Cloud Service ◽  
Cloud Services ◽  
Cloud Environment ◽  
Cloud Service Providers ◽  
Application Programming ◽  
Increasing Demand ◽  
Programming Interfaces ◽  
Multi Cloud

The increasing demand for cloud computing has shifted business toward a huge demand for cloud services, which offer platform, software, and infrastructure for the day-to-day use of cloud consumers. Numerous new cloud service providers have been introduced to the market with unique features that assist service developers collaborate and migrate services among multiple cloud service providers to address the varying requirements of cloud consumers. Many interfaces and proprietary application programming interfaces (API) are available for migration and collaboration services among cloud providers, but lack standardization efforts. The target of the research work was to summarize the issues involved in semantic cloud portability and interoperability in the multi-cloud environment and define the standardization effort imminently needed for migrating and collaborating services in the multi-cloud environment.

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