scholarly journals Dating ancient human samples using the recombination clock

2015 ◽  
Author(s):  
Priya Moorjani ◽  
Sriram Sankararaman ◽  
Qiaomei Fu ◽  
Molly Przeworski ◽  
Nick J Patterson ◽  
...  
Keyword(s):  
Best Practice ◽  
Radiocarbon Dates ◽  
Genetic Method ◽  
Human Samples ◽  
Shared History ◽  
Complementary Approach ◽  
Neanderthal Admixture ◽  
History Of ◽  
The Difference ◽  
Age Estimates

The study of human evolution has been revolutionized by inferences from ancient DNA analyses. Key to these is the reliable estimation of the age of ancient specimens. The current best practice is radiocarbon dating, which relies on characterizing the decay of radioactive carbon isotope (14C), and is applicable for dating up to 50,000-year-old samples. Here, we introduce a new genetic method that uses recombination clock for dating. The key idea is that an ancient genome has evolved less than the genomes of extant individuals. Thus, given a molecular clock provided by the steady accumulation of recombination events, one can infer the age of the ancient genome based on the number of missing years of evolution. To implement this idea, we take advantage of the shared history of Neanderthal gene flow into non-Africans that occurred around 50,000 years ago. Using the Neanderthal ancestry decay patterns, we estimate the Neanderthal admixture time for both ancient and extant samples. The difference in these admixture dates then provides an estimate of the age of the ancient genome. We show that our method provides reliable results in simulations. We apply our method to date five ancient Eurasian genomes with radiocarbon dates ranging between 12,000 to 45,000 years and recover consistent age estimates. Our method provides a complementary approach for dating ancient human samples and is applicable to ancient non-African genomes with Neanderthal ancestry. Extensions of this methodology that use older shared events may be able to date ancient genomes that fall beyond the radiocarbon frontier.

scholarly journals A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years

2016 ◽  
Vol 113 (20) ◽  
pp. 5652-5657 ◽  
Author(s):  
Priya Moorjani ◽  
Sriram Sankararaman ◽  
Qiaomei Fu ◽  
Molly Przeworski ◽  
Nick Patterson ◽  
...  
Keyword(s):  
Upper Paleolithic ◽  
Direct Estimate ◽  
Radiocarbon Dates ◽  
Genetic Method ◽  
Generation Interval ◽  
Neanderthal Admixture ◽  
The Common ◽  
The Mean ◽  
The Difference ◽  
Age Estimates

The study of human evolution has been revolutionized by inferences from ancient DNA analyses. Key to these studies is the reliable estimation of the age of ancient specimens. High-resolution age estimates can often be obtained using radiocarbon dating, and, while precise and powerful, this method has some biases, making it of interest to directly use genetic data to infer a date for samples that have been sequenced. Here, we report a genetic method that uses the recombination clock. The idea is that an ancient genome has evolved less than the genomes of present-day individuals and thus has experienced fewer recombination events since the common ancestor. To implement this idea, we take advantage of the insight that all non-Africans have a common heritage of Neanderthal gene flow into their ancestors. Thus, we can estimate the date since Neanderthal admixture for present-day and ancient samples simultaneously and use the difference as a direct estimate of the ancient specimen’s age. We apply our method to date five Upper Paleolithic Eurasian genomes with radiocarbon dates between 12,000 and 45,000 y ago and show an excellent correlation of the genetic and 14C dates. By considering the slope of the correlation between the genetic dates, which are in units of generations, and the 14C dates, which are in units of years, we infer that the mean generation interval in humans over this period has been 26–30 y. Extensions of this methodology that use older shared events may be applicable for dating beyond the radiocarbon frontier.

The Carmelite Order and Greek Orthodox Monasticism: a Study in Retrospective Unity

1996 ◽  
Vol 32 ◽  
pp. 117-129
Author(s):  
Andrew Jotischky
Keyword(s):  
Greek Orthodox ◽  
Shared History ◽  
History Of ◽  
The Difference

On his embassy from Constantinople to the papal curia in 1339, the Greek Orthodox envoy Barlaam confided to Benedict XII his pessimistic belief that genuine union between the Churches was rendered impossible less by theological difference than by the shared history of relations between eastern and western Christendom: It is not so much the difference in doctrine that alienates the hearts of the Greeks from you as the hatred against the Latins that has entered their souls because of the great number of evils they have suffered at the hands of the Latins at different times, and which they still suffer every day. Unless this hatred is dispelled, union can never be achieved.

scholarly journals The Deposition History of the Coversands along the Bree Fault Escarpment, NE Belgium

2001 ◽  
Vol 80 (3-4) ◽  
pp. 171-185 ◽  
Author(s):  
M. Frechen ◽  
K. Vanneste ◽  
K. Verbeeck ◽  
E. Paulissen ◽  
T. Camelbeeck
Keyword(s):  
Late Quaternary ◽  
Fault Scarp ◽  
Optically Stimulated Luminescence ◽  
Radiocarbon Dates ◽  
Area Of Interest ◽  
History Of ◽  
Late Weichselian ◽  
Set Up ◽  
The Village ◽  
Age Estimates

AbstractThe coversands along the Bree fault escarpment, NE Belgium, were investigated by a combined dating approach including infrared optically stimulated luminescence (IRSL), thermoluminescence (TL) and radiocarbon methods. Four trenches were excavated cutting the fault scarp near the village of Bree in northeast Belgium. Altogether 17 luminescence samples and seven radiocarbon samples were investigated in order to set up a more reliable and precise chronological frame for the local coversand stratigraphy and the timing of Late Quaternary earthquake events. The chronological results indicate at least five accumulation periods for the coversand units in the area of interest. The oldest coversands were deposited during Saalian or Early Weichselian followed by coversands deposited during the Early and/or Middle Weichselian. At least three coversand units can be distinguished for the time span of the Late Weichselian to Holocene. Significant TL age underestimation of more than 20% compared to IRSL was found for samples from Trench 4. Most of the IRSL age estimates are in agreement with radiocarbon dates from the same section.

The Subaltern Speak- A Study On The Culture Of The Arunachalis With Special Reference To Mamang Dai’s The Legends Of Pensam

2019 ◽  
Vol 5 (4) ◽  
pp. 14-20
Author(s):  
Ms. Cheryl Antonette Dumenil ◽  
Dr. Cheryl Davis
Keyword(s):  
Special Reference ◽  
Small World ◽  
Natural World ◽  
Arunachal Pradesh ◽  
North East India ◽  
North East ◽  
Shared History ◽  
History Of ◽  
And Gender ◽  
Insight Into

North- East India is an under veiled region with an awe-inspiring landscape, different groups of ethnic people, their culture and heritage. Contemporary writers from this region aspire towards a vision outside the tapered ethnic channel, and they represent a shared history. In their writings, the cultural memory is showcased, and the intensity of feeling overflows the labour of technique and craft. Mamang Dai presents a rare glimpse into the ecology, culture, life of the tribal people and history of the land of the dawn-lit mountains, Arunachal Pradesh, through her novel The Legends of Pensam. The word ‘Pensam’ in the title means ‘in-between’,  but it may also be interpreted as ‘the hidden spaces of the heart’. This is a small world where anything can happen. Being adherents of the animistic faith, the tribes here believe in co-existence with the natural world along with the presence of spirits in their forests and rivers. This paper attempts to draw an insight into the culture and gender of the Arunachalis with special reference to The Legends of Pensam by Mamang Dai.

Harsdörffers Geschirr

2019 ◽  
Vol 10 (1) ◽  
pp. 23-37
Author(s):  
Natalie Binczek
Keyword(s):  
Design History ◽  
History Of ◽  
The Difference

Der deutsche Barockdichter Georg Philipp Harsdörffer skizziert eine Theorie der Emblematik, die vor allem dessen Anwendungsvielfalt hervorhebt. Er hebt dabei besonders den Unterschied zwischen buchinterner und buchexterner Verwendung auf, indem er sich nicht nur für die Aufnahme der Embleme in Büchern, sondern auch auf Geschirr und Tapeten ausspricht. Der Beitrag liest Harsdörffers extensive Überlegungen nicht nur als Beiträge zur Theorie und Geschichte der Embleme als ›Sinn-Bilder‹, sondern auch als Beitrag zur Designgeschichte. German Baroque poet Georg Philipp Harsdörffer delineates a theory of emblematics that clearly sets itself apart from other contemporary theories, especially by its versatility. In particular, the author negates the difference between internal and external usage of emblems in books not only by promoting the incorporation of emblems into printed works but also by supporting their depiction on dishes and tapestries. This article strives to read Harsdörffer’s extensive thoughts on the matter of emblems not simply as another work on the theory and history of emblematics but rather as a contribution to design history as well

RUSSIAN-BELARUSIAN TUTORIAL "HISTORY OF THE GREAT PATRIOTIC WAR. ESSAYS ON THE SHARED HISTORY"

2020 ◽  
pp. 68-88
Author(s):  
Elena A. Kosovan ◽  
Keyword(s):  
Point Of View ◽  
Joint Work ◽  
Eurasian Economic Union ◽  
Shared History ◽  
Great Patriotic War ◽  
History Of ◽  
Independent States ◽  
The Republic ◽  
Integration Project ◽  
Second World

The paper provides a review on the joint Russian-Belarusian tutorial “History of the Great Patriotic War. Essays on the Shared History” published for the 75th anniversary of the victory in the Great Patriotic War. The tutorial was prepared within the project “Belarus and Russia. Essays on the Shared History”, implemented since 2018 and aimed at publishing a series of tutorials, which authors are major Russian and Belarusian historians, archivists, teachers, and other specialists in human sciences. From the author’s point of view, the joint work of specialists from the Russian Federation and the Republic of Belarus in such a format not only contributes to the deepening of humanitarian integration within the Union state, but also to the formation of a common educational system on the scale of the Commonwealth of Independent States or the Eurasian integration project (Eurasian Economic Union – EEU). The author emphasises the high research and educational significance of the publication reviewed when noting that the teaching of history in general and the history of the Second World War and the Great Patriotic War in particular in post-Soviet schools and institutes of higher education is complicated by many different issues and challenges (including external ones, which can be regarded as information aggression by various extra-regional actors).

Introduction

2017 ◽  
Author(s):  
Simon Kirchin
Keyword(s):  
Hilary Putnam ◽  
Bernard Williams ◽  
General Methodology ◽  
Thick Concepts ◽  
History Of ◽  
Philippa Foot ◽  
The Difference

This chapter introduces the distinction between thin and thick concepts and then performs a number of functions. First, two major accounts of thick concepts—separationism and nonseparationism—are introduced and, in doing so, a novel account of evaluation is indicated. Second, each chapter is outlined as is the general methodology, followed, third, by a brief history of the discussion of thick concepts, referencing Philippa Foot, Hilary Putnam, Gilbert Ryle, and Bernard Williams among others. Fourth, a number of relevant contrasts are introduced, such as the fact–value distinction and the difference between concepts, properties, and terms. Lastly, some interesting and relevant questions are raised that, unfortunately, have to be left aside.

scholarly journals Direct dating reveals the early history of opium poppy in western Europe

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Aurélie Salavert ◽  
Antoine Zazzo ◽  
Lucie Martin ◽  
Ferran Antolín ◽  
Caroline Gauthier ◽  
...  
Keyword(s):  
Western Europe ◽  
Western Alps ◽  
Western Mediterranean ◽  
Opium Poppy ◽  
Radiocarbon Dates ◽  
Macrobotanical Remains ◽  
History Of ◽  
Temperate Europe ◽  
Radiocarbon Chronology ◽  
Botanical Remains

AbstractThis paper aims to define the first chrono-cultural framework on the domestication and early diffusion of the opium poppy using small-sized botanical remains from archaeological sites, opening the way to directly date minute short-lived botanical samples. We produced the initial set of radiocarbon dates directly from the opium poppy remains of eleven Neolithic sites (5900–3500 cal BCE) in the central and western Mediterranean, northwestern temperate Europe, and the western Alps. When possible, we also dated the macrobotanical remains originating from the same sediment sample. In total, 22 samples were taken into account, including 12 dates directly obtained from opium poppy remains. The radiocarbon chronology ranges from 5622 to 4050 cal BCE. The results show that opium poppy is present from at least the middle of the sixth millennium in the Mediterranean, where it possibly grew naturally and was cultivated by pioneer Neolithic communities. Its dispersal outside of its native area was early, being found west of the Rhine in 5300–5200 cal BCE. It was introduced to the western Alps around 5000–4800 cal BCE, becoming widespread from the second half of the fifth millennium. This research evidences different rhythms in the introduction of opium poppy in western Europe.

The Early History of Financial Economics, 1478–1776. By Geoffrey Poitras. Cheltenham and Northampton: Edward Elgar, 2000. Pp. x, 522.

2002 ◽  
Vol 62 (1) ◽  
pp. 268-269
Author(s):  
Larry Neal
Keyword(s):  
Economic History ◽  
Financial Analysis ◽  
Adam Smith ◽  
Economic Thought ◽  
Financial History ◽  
X 522 ◽  
History Of ◽  
The Difference ◽  
Wealth Of Nations ◽  
Simon Fraser University

Economic historians usually have to explain to their economist colleagues the difference between economic history, which focuses on facts, and history of economic thought, which focuses on ideas. Our colleagues in finance departments, typically fascinated by episodes in financial history treated by economic historians, are bound to be disappointed in the lack of attention given to the development of ideas in finance by historians of economic thought. Geoffrey Poitras, a professor of finance at Simon Fraser University, makes a valiant effort to remedy these oversights in his collection of vignettes that highlight the sophistication of financial instruments and analysts of financial markets well before the time of Adam Smith. Starting in 1478 with the publication of the Treviso Arithmetic, a typical textbook of commercial arithmetic for Italian merchants, and ending with brief snippets from the Wealth of Nations, Poitras treats the reader to a fascinating potpourri of excerpts from various manuals, brief biographies of pioneers in financial analysis, and historical discursions on foreign-exchange and stock markets.

scholarly journals Reproducibility and Instruction Following in the Shop Floor Laboratory Work: The Case of a TMS Experiment

2021 ◽  
pp. 016224392110323
Author(s):  
Kristina Popova
Keyword(s):  
Measurement Procedure ◽  
Shop Floor ◽  
Experimental Uncertainty ◽  
Local Measurement ◽  
Replication Crisis ◽  
History Of ◽  
Per Se ◽  
The Difference ◽  
Methodological Guidelines ◽  
Local Procedure

The article addresses the production of reproducibility as a topic that has become acutely relevant in the recent discussions on the replication crisis in science. It brings the ethnomethodological stance on reproducibility into the discussions, claiming that reproducibility is necessarily produced locally, on the shop floor, with methodological guidelines serving as references to already established practices rather than their origins. The article refers to this argument empirically, analyzing how a group of novice neuroscientists performs a series of measurements in a transcranial magnetic stimulation experiment. Based on ethnography and video analysis, the article traces a history of the local measurement procedure invented by the researchers in order to overcome the experimental uncertainty. The article aims to demonstrate (1) how reproducibility of the local procedure is achieved in the shop floor work of the practitioners and (2) how the procedure becomes normalized and questioned as incorrect in the course of experimental practice. It concludes that the difference between guidelines and practical actions is not problematic per se; what may be problematic is that researchers can be engaged in different working projects described by the same instruction.

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