scholarly journals SPONTANEOUS ECHO CONTRAST IN MITRAL STENOSIS: WHY AND HOW?

Author(s):  
Ziya Gokalp Bilgel ◽  
Ibrahim Hakan Gullu ◽  
Saif Hamad ◽  
Mutlu Kasar ◽  
Tansel Erol ◽  
...  

ABSTRACTBackgroundSpontaneous echo contrast(SEC) is an echocardiographic finding particularly found in left atrium of patients with mitral stenosis and known as a risk factor for stroke. However, its pathophysiology is not fully understood.Material and MethodForty-eight patients with mitral stenosis scheluded for percutaneous mitral valvuloplasty were included in the study. SEC was graded from 0 to 4 according to its density. Blood samples were taken from the aorta and left atrium during the procedure. Whole blood viscosity, plasma viscosity(PV) and peripheral blood smears were obtained and analysed separately from these sites. Prior to the procedure, all participants also underwent transthoracic and transesophageal echocardiography.ResultsSevere SEC(grade 3-4) was found in 23 patients(48%), remaining 25 patients(52%) had mild to moderate SEC(grade 0-1-2). The patients with atrial fibrillation(AF) and hypertension(HT) had more significantly severe SEC compared to other patients. Compared to patients with mild to moderate SEC, patients with severe SEC had increased age, body mass index, left atrial diameter, left atrial area and left atrial PV. However, ejection fraction, left atrial appendage(LAA) filling and emptying velocities, LAA lateral wall late systolic velocity, LAA fractional area change and pulmonary vein(PVe) systolic velocity were found to be significantly reduced in patients with severe SEC compared to mild to moderate SEC. On multiple linear regression analysis, AF, left atrium PV and left atrial diameter were the strongly correlated with SEC grade.ConclusionWe have shown that AF, HT, systolic dysfunction of LAA, increased left atrial dimensions, reduced ejection fraction, decreased PVe flow velocity and increased left atrial PV were related with the development of SEC in patients with mitral stenosis.

Author(s):  
Ziya Bilgel ◽  
Hakan gullu ◽  
Saif Hamad ◽  
Mutlu Kasar ◽  
Tansel Erol ◽  
...  

Backround: Spontaneous echo contrast (SEC) is an echocardiographic finding particularly found in left atrium of patients with mitral stenosis (MS) and known as a risk factor for stroke. However, its pathophysiology is not fully understood. Methods: Forty-eight patients with MS scheduled for percutaneous mitral valvuloplasty were included in the study. Blood samples were taken from the aorta and left atrium (LA) during the procedure. Whole blood viscosity (WBV), plasma viscosity (PV) and peripheral blood smears were obtained and analysed separately from these sites. All participants underwent transthoracic and transesophageal echocardiography prior to the procedure Results: Severe SEC (grade 3-4) was found in 23 patients, remaining 25 patients had mild to moderate SEC (grade 0-1-2). Patients with severe SEC had increased LA diameter, area and PV. However, ejection fraction, left atrial appendage (LAA) filling and emptying velocities, LAA lateral wall late systolic velocity, LAA fractional area change and pulmonary vein (PVe) systolic velocity were found to be significantly reduced in patients with severe SEC compared to mild to moderate SEC. On multiple linear regression analysis, atrial fibrillation, left atrium PV and diameter were strongly correlated with SEC grade (Respectively p=0,011, p=0,013, p=0,030). Conclusion: We have shown that AF, systolic dysfunction of LAA and left ventricule, reduced PVe flow velocity, increased LA dimensions and left atrial PV were related with the severity of SEC in patients with mitral stenosis. We demonstrated the relationship between the increase left atrial PV and SEC in addition to impaired hemodynamic determinants in patients with mitral stenosis.


Medicine ◽  
2019 ◽  
Vol 98 (48) ◽  
pp. e18146
Author(s):  
Ning Zhu ◽  
Hao Chen ◽  
Xuyong Zhao ◽  
Fanhao Ye ◽  
Wenbing Jiang ◽  
...  

2019 ◽  
pp. 8-13
Author(s):  
Van Khanh Nguyen Truong ◽  
Anh Vu Nguyen

Background: Heart failure is a common clinical syndrome and is the final stage of most cardiovascular diseases. Nowadays, the role of left atrium in cardiovascular diseases, especially in HF diseases, is more and more important. At the early stage of heart failure, the size and pump function of left atrium are increased. When the left ventricular function is reduced significantly, left atrial function is alo impaired. Aims of the study: assess size and function of left atrium in patient with heart failure reduced ejection fraction (HFrEF). Establishing the association between two indexs above with some clinical and subclinical characteristics. Subjects and method: 51 HFrEF patients in Hospital of Hue University of Medicine and Pharmacy, who have including criteria. Cross-sectional study. Results: LAVI (ml/m2): 43.19 ± 12.48 ml/m2, percentage of large left atrial patents is 80.4%. LATEF (%): 31.93 ± 7.72%. LAVI has correlation with: LVEDV (r= 0,45); LVESV (r= 0,43); NT-proBNP (r= 0.371). There is a difference LAVI of diastolic dysfunction grades (r= 0.011), There is a difference LAVI of NYHA class (r= 0.016). LATEF has correlation with NTproBNP (r= -0.349). Conclusion: The left atrium’s size is increased and its function is reduced in HFrEF patient. There is a positive correlation between LAVI and LVEDV, LVESV, NTproBNP. The LAVI varies with the diastolic dysfunction grade. And there is a negative correlation between LATEF and NTproBNP. Key words: heart failure reduced ejection fraction; size of left atrium, function of left atrium


Author(s):  
Alessandro Malagoli ◽  
Luca Rossi ◽  
Alessia Zanni ◽  
Concetta Sticozzi ◽  
Massimo Francesco Piepoli ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Weiting Huang ◽  
Khaled Mohamed Emadeldin Moheb Hammad ◽  
Victor Tar Toong Chao ◽  
Khung Keong Yeo

The growth in percutaneous transluminal devices has enabled operators to tackle more complex, native, and post-bypass surgery anatomy. However, complications such as coronary artery dissection, coronary perforation, retrograde aortic dissection, arrhythmias, and acute coronary syndrome still occur with resulting mortality rates of up to 4.2% in complex interventions. Perforation of the circumflex artery is of particular interest in view of its position and relation to the surrounding cardiac structures. This is a site of potential fluid collection, and as the left atrium is fixed to the parietal pericardium at the entry of the pulmonary veins, fluid in the oblique sinus can accumulate enough pressure to compress the left atrium and the coronary sinus. We present a case of left circumflex artery perforation which demonstrates the physiologic complications of coronary sinus and left atrial compression and the resultant functional mitral stenosis.


Kardiologiia ◽  
2021 ◽  
Vol 61 (8) ◽  
pp. 68-75
Author(s):  
E. K. Serezhina ◽  
A. G. Obrezan

This systematic review is based on 19 studies from Elsevier, PubMed, Embase, and Scopus databases, which were found by the following keywords: LA strain (left atrial strain), STE (speckle tracking echocardiography), HF (heart failure), and HFpEF (heart failure with preserved ejection fraction). The review focuses on results and conclusions of studies on using the 2D echocardiographic evaluation of left atrial (LA) myocardial strain for early diagnosis of HFpEF in routine clinical practice. Analysis of the studies included into this review showed a significant decline of all LA functions in patients with HFpEF. Also, multiple studies have reported associations between decreased indexes of LA strain and old age, atrial fibrillation, left ventricular hypertrophy, left and right ventricular systolic dysfunction, and LV diastolic dysfunction. Thus, the review indicates significant possibilities of using indexes of LA strain in evaluation of early stages of both systolic and diastolic myocardial dysfunction. Notably, LA functional systolic and diastolic indexes are not sufficiently studied despite their growing significance for diagnosis and prognosis of patients with HFpEF. For this reason, in addition to existing models for risk stratification in this disease, including clinical characteristics and/or echocardiographic data, future studies should focus on these parameters. 


2019 ◽  
Vol 25 (2) ◽  
pp. 87-96 ◽  
Author(s):  
Daniel Modin ◽  
Morten Sengeløv ◽  
Peter Godsk Jørgensen ◽  
Flemming Javier Olsen ◽  
Niels Eske Bruun ◽  
...  

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