scholarly journals Cell-to-cell Mathematical Modeling of Arrhythmia Phenomena in the Heart

2020 ◽  
Author(s):  
Gabriel López Garza ◽  
A. Nicolás Mata ◽  
G. Román Alonso ◽  
J. F. Godínez Fernández ◽  
M. A. Castro García

AbstractWith an aperiodic, self-similar distribution of two-dimensional arrangement of atrial cells, it is possible to simulate such phenomena as Fibrillation, Fluttering, and a sequence of Fibrillation-Fluttering. The topology of a network of cells may facilitate the initiation and development of arrhythmias such as Fluttering and Fibrillation. Using a GPU parallel architecture, two basic cell topologies were considered in this simulation, an aperiodic, fractal distribution of connections among 462 cells, and a chessboard-like geometry of 60×60 and 600×600 cells. With a complex set of initial conditions, it is possible to produce tissue behavior that may be identified with arrhythmias. Finally, we found several sets of initial conditions that show how a mesh of cells may exhibit Fibrillation that evolves into Fluttering.

2019 ◽  
Author(s):  
Gabriel López Garza

AbstractIn this document are modeled arrhythmias with cellular automaton and ordinary differential equations systems. With an aperiodic, self-similar distribution of two-dimensional arrangement of cells, it is possible to simulate such phenomena as fibrillation, fluttering and a sequence of fibrillation-fluttering. The topology of the cytoarchitecture of a network of cells may determine the initiation and development of arrhythmias.


2015 ◽  
Vol 82 (7) ◽  
Author(s):  
H. Song ◽  
R. J. Dikken ◽  
L. Nicola ◽  
E. Van der Giessen

Part of the friction between two rough surfaces is due to the interlocking between asperities on opposite surfaces. In order for the surfaces to slide relative to each other, these interlocking asperities have to deform plastically. Here, we study the unit process of plastic ploughing of a single micrometer-scale asperity by means of two-dimensional dislocation dynamics simulations. Plastic deformation is described through the generation, motion, and annihilation of edge dislocations inside the asperity as well as in the subsurface. We find that the force required to plough an asperity at different ploughing depths follows a Gaussian distribution. For self-similar asperities, the friction stress is found to increase with the inverse of size. Comparison of the friction stress is made with other two contact models to show that interlocking asperities that are larger than ∼2 μm are easier to shear off plastically than asperities with a flat contact.


1975 ◽  
Vol 69 (3) ◽  
pp. 417-443 ◽  
Author(s):  
Peter B. Rhines

Two-dimensional eddies in a homogeneous fluid at large Reynolds number, if closely packed, are known to evolve towards larger scales. In the presence of a restoring force, the geophysical beta-effect, this cascade produces a field of waves without loss of energy, and the turbulent migration of the dominant scale nearly ceases at a wavenumber kβ = (β/2U)½ independent of the initial conditions other than U, the r.m.s. particle speed, and β, the northward gradient of the Coriolis frequency.The conversion of turbulence into waves yields, in addition, more narrowly peaked wavenumber spectra and less fine-structure in the spatial maps, while smoothly distributing the energy about physical space.The theory is discussed, using known integral constraints and similarity solutions, model equations, weak-interaction wave theory (which provides the terminus for the cascade) and other linearized instability theory. Computer experiments with both finite-difference and spectral codes are reported. The central quantity is the cascade rate, defined as \[ T = 2\int_0^{\infty} kF(k)dk/U^3\langle k\rangle , \] where F is the nonlinear transfer spectrum and 〈k〉 the mean wavenumber of the energy spectrum. (In unforced inviscid flow T is simply U−1d〈k〉−1/dt, or the rate at which the dominant scale expands in time t.) T is shown to have a mean value of 3·0 × 10−2 for pure two-dimensional turbulence, but this decreases by a factor of five at the transition to wave motion. We infer from weak-interaction theory even smaller values for k [Lt ] kβ.After passing through a state of propagating waves, the homogeneous cascade tends towards a flow of alternating zonal jets which, we suggest, are almost perfectly steady. When the energy is intermittent in space, however, model equations show that the cascade is halted simply by the spreading of energy about space, and then the end state of a zonal flow is probably not achieved.The geophysical application is that the cascade of pure turbulence to large scales is defeated by wave propagation, helping to explain why the energy-containing eddies in the ocean and atmosphere, though significantly nonlinear, fail to reach the size of their respective domains, and are much smaller. For typical ocean flows, $k_{\beta}^{-1} = 70\,{\rm km} $, while for the atmosphere, $k_{\beta}^{-1} = 1000\,{\rm km}$. In addition the cascade generates, by itself, zonal flow (or more generally, flow along geostrophic contours).


2013 ◽  
Vol 2013 ◽  
pp. 1-13
Author(s):  
Motoaki Saruwatari ◽  
Masa-aki Hashimoto ◽  
Ryohei Fukuda ◽  
Shin-ichiro Fujimoto

We investigate the r-process nucleosynthesis during the magnetohydrodynamical (MHD) explosion of a supernova in a helium star of 3.3 M⊙, where effects of neutrinos are taken into account using the leakage scheme in the two-dimensional (2D) hydrodynamic code. Jet-like explosion due to the combined effects of differential rotation and magnetic field is able to erode the lower electron fraction matter from the inner layers. We find that the ejected material of low electron fraction responsible for the r-process comes out from just outside the neutrino sphere deep inside the Fe-core. It is found that heavy element nucleosynthesis depends on the initial conditions of rotational and magnetic fields. In particular, the third peak of the distribution is significantly overproduced relative to the solar system abundances, which would indicate a possible r-process site owing to MHD jets in supernovae.


2001 ◽  
Vol 7 (3) ◽  
pp. 253-282 ◽  
Author(s):  
Ch. Srinivasa Rao ◽  
P. L. Sachdev ◽  
Mythily Ramaswamy

The nonlinear ordinary differential equation resulting from the self-similar reduction of a generalized Burgers equation with nonlinear damping is studied in some detail. Assuming initial conditions at the origin we observe a wide variety of solutions – (positive) single hump, unbounded or those with a finite zero. The existence and nonexistence of positive bounded solutions with different types of decay (exponential or algebraic) to zero at infinity for specific parameter ranges are proved.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Peixiao Zheng ◽  
Gaoming Jiang ◽  
Honglian Cong

Abstract Recently, there is an increasing interest in design of circular weft jacquard because of the pursuit of fashion and comfort. Aiming at the complexity of the computer-aided design method of the existing circular weft-knitted jacquard fabrics, which is not conducive to the rapid design and intelligible for designers, a design method was proposed to transform pattern notation into knitting diagram efficiently, which was based on knitting rules and its creation as a set of jacquard modules. Knitting characteristics of jacquard fabrics were studied as a precondition. On this basis, the design procedures of jacquard modules were analyzed and illustrated by taking tricolor bird's eye backing jacquard as an example. Jacquard modules with various jacquard effects were designed and stored in a jacquard module database. To mathematically describe pattern notation, knitting diagram, and jacquard module, two-dimensional matrixes were established by the method of mathematical modeling, and a corresponding algorithm for the transformation of the pattern to knitting information according to the knitting rules of jacquard modules, which can be applied to ordinary jacquard fabrics was summarized. The project of tricolor circular weft-knitted jacquard with bird's eye in the reverse and four-color air-layer jacquard were taken for instance to verify the models and algorithm. The results obtained show that the approach can efficiently and conveniently realize the designation and machine-knitting of weft-knitted jacquard fabric, which provide a theoretical basis and notation of modeling for the computer-aided design of circular weft-knitted jacquard fabrics.


2009 ◽  
Vol 2009 ◽  
pp. 1-22 ◽  
Author(s):  
Edson D. Leonel

A phase transition from integrability to nonintegrability in two-dimensional Hamiltonian mappings is described and characterized in terms of scaling arguments. The mappings considered produce a mixed structure in the phase space in the sense that, depending on the combination of the control parameters and initial conditions, KAM islands which are surrounded by chaotic seas that are limited by invariant tori are observed. Some dynamical properties for the largest component of the chaotic sea are obtained and described in terms of the control parameters. The average value and the deviation of the average value for chaotic components of a dynamical variable are described in terms of scaling laws, therefore critical exponents characterizing a scaling function that describes a phase transition are obtained and then classes of universality are characterized. The three models considered are: The Fermi-Ulam accelerator model, a periodically corrugate waveguide, and variant of the standard nontwist map.


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