scholarly journals CRIMSON: An Open-Source Software Framework for Cardiovascular Integrated Modelling and Simulation

2020 ◽  
Author(s):  
C.J. Arthurs ◽  
R. Khlebnikov ◽  
A. Melville ◽  
M. Marčan ◽  
A. Gomez ◽  
...  
Keyword(s):  
Open Source ◽  
Mesh Generation ◽  
Simulation Software ◽  
Modelling And Simulation ◽  
Integrated Modelling ◽  
Software Environment ◽  
Element Mesh ◽  
Wide Audience ◽  
Link Type ◽  
Computational Haemodynamics

AbstractIn this work, we describe the CRIMSON (CardiovasculaR Integrated Modelling and SimulatiON) software environment. CRIMSON provides a powerful, customizable and user-friendly system for performing three-dimensional and reduced-order computational haemodynamics studies via a pipeline which involves: 1) segmenting vascular structures from medical images; 2) constructing analytic arterial and venous geometric models; 3) performing finite element mesh generation; 4) designing, and 5) applying boundary conditions; 6) running incompressible Navier-Stokes simulations of blood flow with fluid-structure interaction capabilities; and 7) post-processing and visualizing the results, including velocity, pressure and wall shear stress fields. A key aim of CRIMSON is to create a software environment that makes powerful computational haemodynamics tools accessible to a wide audience, including clinicians and students, both within our research laboratories and throughout the community. The overall philosophy is to leverage best-in-class open source standards for medical image processing, parallel flow computation, geometric solid modelling, data assimilation, and mesh generation. It is actively used by researchers in Europe, North and South America, Asia, and Australia. It has been applied to numerous clinical problems; we illustrate applications of CRIMSON to real-world problems using examples ranging from pre-operative surgical planning to medical device design optimization. CRIMSON binaries for Microsoft Windows 10, documentation and example input files are freely available for download from www.crimson.software, and the source code with compilation instructions is available on GitHub https://github.com/carthurs/CRIMSONFlowsolver (CRIMSON Flowsolver) under the GPL v3.0 license, and https://github.com/carthurs/CRIMSONGUI (CRIMSON GUI), under the AGPL v3.0 license. Support is available on the CRIMSON Google Groups forum, located at https://groups.google.com/forum/#!forum/crimson-users.

scholarly journals CRIMSON: An open-source software framework for cardiovascular integrated modelling and simulation

2021 ◽  
Vol 17 (5) ◽  
pp. e1008881
Author(s):  
Christopher J. Arthurs ◽  
Rostislav Khlebnikov ◽  
Alex Melville ◽  
Marija Marčan ◽  
Alberto Gomez ◽  
...  
Keyword(s):  
Open Source ◽  
Mesh Generation ◽  
Three Dimensional ◽  
Simulation Software ◽  
Modelling And Simulation ◽  
Integrated Modelling ◽  
Software Environment ◽  
Element Mesh ◽  
Wide Audience ◽  
Computational Haemodynamics

In this work, we describe the CRIMSON (CardiovasculaR Integrated Modelling and SimulatiON) software environment. CRIMSON provides a powerful, customizable and user-friendly system for performing three-dimensional and reduced-order computational haemodynamics studies via a pipeline which involves: 1) segmenting vascular structures from medical images; 2) constructing analytic arterial and venous geometric models; 3) performing finite element mesh generation; 4) designing, and 5) applying boundary conditions; 6) running incompressible Navier-Stokes simulations of blood flow with fluid-structure interaction capabilities; and 7) post-processing and visualizing the results, including velocity, pressure and wall shear stress fields. A key aim of CRIMSON is to create a software environment that makes powerful computational haemodynamics tools accessible to a wide audience, including clinicians and students, both within our research laboratories and throughout the community. The overall philosophy is to leverage best-in-class open source standards for medical image processing, parallel flow computation, geometric solid modelling, data assimilation, and mesh generation. It is actively used by researchers in Europe, North and South America, Asia, and Australia. It has been applied to numerous clinical problems; we illustrate applications of CRIMSON to real-world problems using examples ranging from pre-operative surgical planning to medical device design optimization.

scholarly journals Open source tools for geographic analysis in transport planning

2021 ◽  
Author(s):  
Robin Lovelace
Keyword(s):  
User Interface ◽  
Open Source ◽  
Citizen Participation ◽  
Simulation Software ◽  
First Century ◽  
Transport Planning ◽  
Geographic Analysis ◽  
Link Type ◽  
Twenty First Century ◽  
Interactive Map

AbstractGeographic analysis has long supported transport plans that are appropriate to local contexts. Many incumbent ‘tools of the trade’ are proprietary and were developed to support growth in motor traffic, limiting their utility for transport planners who have been tasked with twenty-first century objectives such as enabling citizen participation, reducing pollution, and increasing levels of physical activity by getting more people walking and cycling. Geographic techniques—such as route analysis, network editing, localised impact assessment and interactive map visualisation—have great potential to support modern transport planning priorities. The aim of this paper is to explore emerging open source tools for geographic analysis in transport planning, with reference to the literature and a review of open source tools that are already being used. A key finding is that a growing number of options exist, challenging the current landscape of proprietary tools. These can be classified as command-line interface, graphical user interface or web-based user interface tools and by the framework in which they were implemented, with numerous tools released as R, Python and JavaScript packages, and QGIS plugins. The review found a diverse and rapidly evolving ‘ecosystem’ tools, with 25 tools that were designed for geographic analysis to support transport planning outlined in terms of their popularity and functionality based on online documentation. They ranged in size from single-purpose tools such as the QGIS plugin AwaP to sophisticated stand-alone multi-modal traffic simulation software such as MATSim, SUMO and Veins. Building on their ability to re-use the most effective components from other open source projects, developers of open source transport planning tools can avoid ‘reinventing the wheel’ and focus on innovation, the ‘gamified’ A/B Street https://github.com/dabreegster/abstreet/#abstreet simulation software, based on OpenStreetMap, a case in point. The paper, the source code of which can be found at https://github.com/robinlovelace/open-gat, concludes that, although many of the tools reviewed are still evolving and further research is needed to understand their relative strengths and barriers to uptake, open source tools for geographic analysis in transport planning already hold great potential to help generate the strategic visions of change and evidence that is needed by transport planners in the twenty-first century.

scholarly journals Improving COVID-19 vaccination centre operation through computer modelling and simulation

2021 ◽  
Author(s):  
RM Wood ◽  
SJ Moss ◽  
BJ Murch ◽  
C Davies ◽  
C Vasilakis
Keyword(s):  
Open Source ◽  
Economic Activity ◽  
Computer Modelling ◽  
Early Stage ◽  
Healthcare Services ◽  
Simulation Software ◽  
Mass Vaccination ◽  
Modelling And Simulation ◽  
Historical Experience

AbstractMass vaccination is widely considered to offer the only route out of the COVID-19 pandemic in a way that social restrictions can be eased and economic activity can safely resume without compromising healthcare services. For many countries, dedicated vaccination centres are a key part of that effort. However, with no directly comparable historical experience there is little information to guide the operational configuration and management of these sites. In addressing this gap in knowledge, the objective of this study is to demonstrate the value of computer modelling. This is achieved through providing an account of its use in supporting management considerations and decisions at two major vaccination centres, at an early stage of the UK’s mass vaccination effort. We report on how modelling insight has influenced the initial setup of one site, including quantification of daily booking numbers. For the same site, we reveal how analysis has informed a significant operational shift in combining two key activities on the vaccination pathway into one. Finally, we describe how, at a second site, modelling has been used to examine pathway stability, in terms of resilience to unforeseen ‘shocks’ such as delayed arrivals and staff unavailability. Alongside the open-source simulation software, the modelling insights reported here can support managers to better plan and improve the operation of COVID-19 vaccination centres.

scholarly journals Virtual Cell modelling and simulation software environment

2008 ◽  
Vol 2 (5) ◽  
pp. 352-362 ◽  
Author(s):  
I.I. Moraru ◽  
F. Morgan ◽  
Y. Li ◽  
L.M. Loew ◽  
J.C. Schaff ◽  
...  
Keyword(s):  
Simulation Software ◽  
Modelling And Simulation ◽  
Software Environment ◽  
Virtual Cell

scholarly journals Solution of Bottlenecks in the Logistics Flow by Applying the Kanban Module in the Tecnomatix Plant Simulation Software

2021 ◽  
Vol 13 (14) ◽  
pp. 7989
Author(s):  
Miriam Pekarcikova ◽  
Peter Trebuna ◽  
Marek Kliment ◽  
Michal Dic
Keyword(s):  
Lean Manufacturing ◽  
Business Processes ◽  
Software Tool ◽  
Transportation Systems ◽  
Simulation Software ◽  
Simulation Methods ◽  
Software Environment ◽  
Production Logistics ◽  
Pull System ◽  
Plant Simulation

The presented article deals with the issue of solving bottlenecks in the logistics flow of a manufacturing company. The Tx Plant Simulation software tool is used to detect bottlenecks and deficiencies in the company’s production, logistics and transportation systems. Together with the use of simulation methods and lean manufacturing tools, losses in business processes are eliminated and consequently flow throughput is improved. In the TX Plant Simulation software environment, using Bottleneck analyzer, bottlenecks were defined on the created simulation model and a method of optimizing logistics flows was designed and tested by introducing the Kanban pull system. This resulted in an improvement and throughput of the entire logistics flow, a reduction in inter-operational stocks and an increase in the efficiency of the production system as a whole.

Modeling of a Steam Turbine Including Partial Arc Admission for Use in a Process Simulation Software Environment

2011 ◽  
Author(s):  
Eric Liese
Keyword(s):  
Steam Turbine ◽  
Process Simulation ◽  
Process Model ◽  
Constant Pressure ◽  
Pressure Ratio ◽  
Simulation Software ◽  
State Variables ◽  
Steam Turbines ◽  
Software Environment ◽  
Last Stage

A dynamic process model of a steam turbine, including partial arc admission operation, is presented. Models were made for the first stage and last stage, with the middle stages presently assumed to have a constant pressure ratio and efficiency. A condenser model is also presented. The paper discusses the function and importance of the steam turbines entrance design and the first stage. The results for steam turbines with a partial arc entrance are shown, and compare well with experimental data available in the literature, in particular, the “valve loop” behavior as the steam flow rate is reduced. This is important to model correctly since it significantly influences the downstream state variables of the steam, and thus the characteristic of the entire steam turbine, e.g., state conditions at extractions, overall turbine flow, and condenser behavior. The importance of the last stage (the stage just upstream of the condenser) in determining the overall flowrate and exhaust conditions to the condenser is described and shown via results.

Finite Element Mesh Generator Applying Constraints’ Propagation and Isoparametric Mapping

1991 ◽  
Author(s):  
J. Rodriguez ◽  
M. Him
Keyword(s):  
Finite Element ◽  
Mesh Generation ◽  
Element Model ◽  
Finite Element Mesh ◽  
Fe Model ◽  
Element Analysis ◽  
Element Mesh ◽  
Mesh Generator ◽  
Generation Algorithm ◽  
Essential Input

Abstract This paper presents a finite element mesh generation algorithm (PREPAT) designed to automatically discretize two-dimensional domains. The mesh generation algorithm is a mapping scheme which creates a uniform isoparametric FE model based on a pre-partitioned domain of the component. The proposed algorithm provides a faster and more accurate tool in the pre-processing phase of a Finite Element Analysis (FEA). A primary goal of the developed mesh generator is to create a finite element model requiring only essential input from the analyst. As a result, the generator code utilizes only a sketch, based on geometric primitives, and information relating to loading/boundary conditions. These conditions represents the constraints that are propagated throughout the model and the available finite elements are uniformly mapped in the resulting sub-domains. Relative advantages and limitations of the mesh generator are discussed. Examples are presented to illustrate the accuracy, efficiency and applicability of PREPAT.

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