scholarly journals Consciousness is supported by near-critical cortical electrodynamics

2021 ◽  
Author(s):  
Daniel Toker ◽  
Ioannis Pappas ◽  
Janna D. Lendner ◽  
Joel Frohlich ◽  
Diego M. Mateos ◽  
...  
Keyword(s):  
Critical Point ◽  
Cortical Dynamics ◽  
Information Richness ◽  
Edge Of Chaos ◽  
Eeg Recordings ◽  
First Time ◽  
Flow Of Information ◽  
Behavior Supports ◽  
Cortical Information Processing ◽  
Do So

Mounting evidence suggests that during conscious states, the electrodynamics of the cortex are poised near a critical point or phase transition, and that this near-critical behavior supports the vast flow of information through cortical networks during conscious states. Here, for the first time, we empirically identify the specific critical point near which conscious cortical dynamics operate as the edge-of-chaos critical point, or the boundary between stability and chaos. We do so by applying the recently developed modified 0-1 chaos test to electrocorticography (ECoG) and magnetoencephalography (MEG) recordings from the cortices of humans and macaques across normal waking, generalized seizure, GABAergic anesthesia, and psychedelic states. Our evidence suggests that cortical information processing is disrupted during unconscious states because of a transition of cortical dynamics away from this critical point; conversely, we show that psychedelics may increase the information-richness of cortical activity by tuning cortical electrodynamics closer to this critical point. Finally, we analyze clinical electroencephalography (EEG) recordings from patients with disorders of consciousness (DOC), and show that assessing the proximity of cortical electrodynamics to the edge-of-chaos critical point may be clinically useful as a new biomarker of consciousness.

In the Labyrinth

2017 ◽  
Author(s):  
Andrew McNeillie
Keyword(s):  
The Right ◽  
First Time ◽  
Do So

It is now widely acknowledged, and far beyond Ireland, that Tim Robinson’s two volumes jointly known as Stones of Aran (‘Pilgrimage’ and ‘Labyrinth’) are modern classics, exemplary in every way of how to write about place and to do so with a formal, literary accomplishment that more than earns the right to nod at Ruskin’s own classic. In 2012, Robinson went back to Árainn, the largest of the three islands, for the first time in nearly ten years. He did so at the urging of Andrew McNeillie, with whom he spent two and a half days revisiting old haunts. This chapter makes account of the occasion and uses, in the process, a unique document provided by Robinson as an experiment in annotating his work. This prompts McNeillie to investigate some of his own annotations and footnotes to Aran.

Reconstituting the International, 1918–1923

2017 ◽  
Author(s):  
Talbot C. Imlay
Keyword(s):  
Seismic Events ◽  
Great War ◽  
Bolshevik Revolution ◽  
Meaning And Purpose ◽  
Post War ◽  
The Impact ◽  
First Time ◽  
The Great War ◽  
Do So ◽  
Lengthy Process

This chapter examines the post-war efforts of European socialists to reconstitute the Socialist International. Initial efforts to cooperate culminated in an international socialist conference in Berne in February 1919 at which socialists from the two wartime camps met for the first time. In the end, however, it would take four years to reconstitute the International with the creation of the Labour and Socialist International (LSI) in 1923. That it took so long to do so is a testimony to the impact of the Great War and to the Bolshevik revolution. Together, these two seismic events compelled socialists to reconsider the meaning and purpose of socialism. The search for answers sparked prolonged debates between and within the major parties, profoundly reconfiguring the pre-war world of European socialism. One prominent stake in this lengthy process, moreover, was the nature of socialist internationalism—both its content and its functioning.

scholarly journals Breast Cancer Cell Re-Dissemination from Lung Metastases—A Mechanism for Enhancing Metastatic Burden

2021 ◽  
Vol 10 (11) ◽  
pp. 2340
Author(s):  
Lucia Borriello ◽  
John Condeelis ◽  
David Entenberg ◽  
Maja H. Oktay
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Metastatic Disease ◽  
Breast Cancer Cells ◽  
Lung Metastases ◽  
Primary Tumors ◽  
Metastatic Burden ◽  
First Time ◽  
Do So

Although metastatic disease is the primary cause of mortality in cancer patients, the mechanisms leading to overwhelming metastatic burden are still incompletely understood. Metastases are the endpoint of a series of multi-step events involving cancer cell intravasation, dissemination to distant organs, and outgrowth to metastatic colonies. Here we show, for the first-time, that breast cancer cells do not solely disseminate to distant organs from primary tumors and metastatic nodules in the lymph nodes, but also do so from lung metastases. Thus, our findings indicate that metastatic dissemination could continue even after the removal of the primary tumor. Provided that the re-disseminated cancer cells initiate growth upon arrival to distant sites, cancer cell re-dissemination from metastatic foci could be one of the crucial mechanisms leading to overt metastases and patient demise. Therefore, the development of new therapeutic strategies to block cancer cell re-dissemination would be crucial to improving survival of patients with metastatic disease.

Some Palaeoliths from South Arabia

1954 ◽  
Vol 19 (2) ◽  
pp. 189-218 ◽  
Author(s):  
G. Caton-Thompson
Keyword(s):  
Geographical Society ◽  
South Arabia ◽  
First Time ◽  
Do So

The material here described was found in the Hadhramaut by Elinor Gardner and myself between November 1937 and March 1938. My personal investigation of the Palaeolithic Age was limited by pre-Islamic excavations, and I am therefore indebted to her for the gathering of most of the specimens in situ in terrace gravels, and to her detailed study of their positions.The collection consists mainly of groups from four fairly widely separated localities; the physiography of these has already been outlined in a comprehensive paper published in the Geographical Journal. Whenever appropriate to the purpose of this account, which is to place for the first time on illustrated record all we observed about the palaeoliths, I have reused in this different context illustrations of Quaternary environment which appeared in that Journal. With thanks I acknowledge the permission of the Royal Geographical Society to do so.

scholarly journals METODE INTERAKSI PARENTING: UPAYA MENGOPTIMALKAN PENDIDIKAN SISWA SEJAK DINI

2016 ◽  
Vol 3 (02) ◽  
Author(s):  
Moh Rifai
Keyword(s):  
Life Cycle ◽  
Elementary Students ◽  
Key Words ◽  
Well Being ◽  
Good Schools ◽  
Children Education ◽  
First Time ◽  
Do So ◽  
The Way

<p>Parents are obliged to take care of their children’s future, especially by rendering sufficient education. Children are believed to bring about happiness every now and then, who generate family’s pride up to the almighty judication. Some people are save and some are not in that court, where children will give sigificant contribution in it. That’s why the children’s well being has become the parents obligation. To bring about children’s well being, parents should also render the good treatments during the life cycle of their children. The main duties of parents for their children are giving them the good names, sending them to the good schools where they can learn religion, and marry them to their good spouses. Psychologically, when children are sent to school for the first time, they will feel that they are put apart from parents’ care, so that may of them have to go difficult phase of adjustment. The adjustment includes that of education so as to run as naturally as possible. To get the naturality of the education delegation, teachers and educators are obliged to be able to nurture any value to students as naturally as possible. Parenting model of teaching serves the requirements of teaching children just the way the parrents do, so that it is assumptively effective in teaching elementary students by taking consideration on the psychologial aspect of children.</p><p> </p><p>Key words:   Parenting Model of teaching, children education optimalization</p>

scholarly journals TAMENESS FROM LARGE CARDINAL AXIOMS

2014 ◽  
Vol 79 (4) ◽  
pp. 1092-1119 ◽  
Author(s):  
WILL BONEY
Keyword(s):  
Large Cardinals ◽  
Large Cardinal ◽  
Strongly Compact Cardinal ◽  
Weakly Compact ◽  
Compact Cardinal ◽  
Dual Property ◽  
First Time ◽  
Strongly Compact Cardinals ◽  
Do So

AbstractWe show that Shelah’s Eventual Categoricity Conjecture for successors follows from the existence of class many strongly compact cardinals. This is the first time the consistency of this conjecture has been proven. We do so by showing that every AEC withLS(K) below a strongly compact cardinalκis <κ-tame and applying the categoricity transfer of Grossberg and VanDieren [11]. These techniques also apply to measurable and weakly compact cardinals and we prove similar tameness results under those hypotheses. We isolate a dual property to tameness, calledtype shortness, and show that it follows similarly from large cardinals.

scholarly journals Honeybee navigation: following routes using polarized-light cues

2011 ◽  
Vol 366 (1565) ◽  
pp. 703-708 ◽  
Author(s):  
P. Kraft ◽  
C. Evangelista ◽  
M. Dacke ◽  
T. Labhart ◽  
M. V. Srinivasan
Keyword(s):  
Apis Mellifera ◽  
Food Source ◽  
Polarized Light ◽  
Light Illumination ◽  
Directional Information ◽  
First Time ◽  
Behavioural Evidence ◽  
Do So

While it is generally accepted that honeybees ( Apis mellifera ) are capable of using the pattern of polarized light in the sky to navigate to a food source, there is little or no direct behavioural evidence that they actually do so. We have examined whether bees can be trained to find their way through a maze composed of four interconnected tunnels, by using directional information provided by polarized light illumination from the ceilings of the tunnels. The results show that bees can learn this task, thus demonstrating directly, and for the first time, that bees are indeed capable of using the polarized-light information in the sky as a compass to steer their way to a food source.

EXISTENCE RESULTS FOR FRACTIONAL BOUNDARY VALUE PROBLEM VIA CRITICAL POINT THEORY

2012 ◽  
Vol 22 (04) ◽  
pp. 1250086 ◽  
Author(s):  
FENG JIAO ◽  
YONG ZHOU
Keyword(s):  
Boundary Value Problem ◽  
Critical Point ◽  
Critical Point Theory ◽  
Existence Of Solutions ◽  
Boundary Value ◽  
Point Theory ◽  
Fractional Boundary Value Problem ◽  
Fractional Differential ◽  
Left And Right ◽  
First Time

In this paper, by the critical point theory, the boundary value problem is discussed for a fractional differential equation containing the left and right fractional derivative operators, and various criteria on the existence of solutions are obtained. To the authors' knowledge, this is the first time, the existence of solutions to the fractional boundary value problem is dealt with by using critical point theory.

How connected is the intuitionistic continuum?

1997 ◽  
Vol 62 (4) ◽  
pp. 1147-1150 ◽  
Author(s):  
Dirk Van Dalen
Keyword(s):  
Real Function ◽  
Peculiar Feature ◽  
Constructive Mathematics ◽  
Fan Theorem ◽  
First Time ◽  
Uniformly Continuous ◽  
Intuitionistic Mathematics ◽  
Excluded Middle ◽  
Do So ◽  
The Continuum

In the twenties Brouwer established the well-known continuity theorem “every real function is locally uniformly continuous,” [3, 2, 5]. From this theorem one immediately concludes that the continuum is indecomposable (unzerlegbar), i.e., if ℝ = A ∪ B and A ∩ B = ∅ (denoted by ℝ = A + B), then ℝ = A or ℝ = B.Brouwer deduced the indecomposability directly from the fan theorem (cf. the 1927 Berline Lectures, [7, p. 49]).The theorem was published for the first time in [6], it was used to refute the principle of the excluded middle: ¬∀x ∈ ℝ (x ∈ ℚ ∨ ¬x ∈ ℚ).The indecomposability of ℝ is a peculiar feature of constructive universa, it shows that ℝ is much more closely knit in constructive mathematics, than in classically mathematics. The classically comparable fact is the topological connectedness of ℝ. In a way this characterizes the position of ℝ: the only (classically) connected subsets of ℝ are the various kinds of segments. In intuitionistic mathematics the situation is different; the continuum has, as it were, a syrupy nature, one cannot simply take away one point. In the classical continuum one can, thanks to the principle of the excluded third, do so. To put it picturesquely, the classical continuum is the frozen intuitionistic continuum. If one removes one point from the intuitionistic continuum, there still are all those points for which it is unknown whether or not they belong to the remaining part.

scholarly journals Choice blindness and choice-induced preference change in groups

2020 ◽  
Author(s):  
Philip Pärnamets ◽  
Jorina von Zimmermann ◽  
Ramsey Raafat ◽  
Gabriel Vogel ◽  
Lars Hall ◽  
...  
Keyword(s):  
Response Time ◽  
Selection Task ◽  
Common Belief ◽  
Group Level ◽  
Preference Change ◽  
False Feedback ◽  
Choice Blindness ◽  
First Time ◽  
Do So

Contrary to common belief, our preferences do not only shape our decisions but are also shaped by what decisions we make. This effect, known as choice-induced preference change, has been extensively studied in individuals. Here we document choice-induced preference change in groups. We do so by using the choice-blindness paradigm, a method by which participants are given false feedback about their past choices. Participants are given a second round of choices following the choice blindness manipulation´measuring preference change resulting from accepting the manipulation. In Experiment 1 (N=83), we introduce a roommate selection task used in this paper and use it to replicate choice-induced preference change using choice-blindness in individuals. In Experiment 2 (N=160), dyad members made mutual choices in the roommate selection task and then receive either veridical or false feedback about what choice they made. The majority of the false feedback trials were accepted by the dyads as their own choices, thereby demonstrating choice blindness in dyads for the first time. Dyads exhibited choice-induced preference change and were more likely to choose the originally rejected option on trials where they accepted the manipulation compared to control trials. In Experiment 3 (N=80), we show that the preference effect induced by the choice blindness manipulation at the group level does not generalize back to follow up choices made by individual participants when removed from the group. In all studies, response time analyses further support our conclusions. Choice-induced preference change exists for both individuals and groups, but the level at which the choice was made constrains the influence of that choice on later preferences.

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