scholarly journals ChAdOx1 n-COV-19 Vaccine Side Effects Among Health Care Workers in Trinidad and Tobago

Author(s):  
Chavin D Gopaul ◽  
Dale Ventour ◽  
Davlin Thomas

Background: The pharmaceutical firms have been lauded for the swift development, trial, approval, and rollout of various Covid-19 vaccines. However, a key issue in the vaccination campaign relates to vaccine hesitancy due to concerns on Covid-19 vaccines safety. Method: A retrospective longitudinal study was carried out via a telephone validated questionnaire among Health Care Workers in Trinidad and Tobago. The questionnaire domains included demographic data, medical and COVID-19 related anamneses, and local and systemic side effects 48 hours after receiving the first dose of the vaccine and 48 hours after receiving the second dose of the vaccine. Results: The questionnaire was administered to a sample of 687 healthcare workers (Male = 275; Female = 412). The results indicated that the incidence of reported fever, body pain, chills, nausea, myalgia, headache, malaise, fatigue and other systemic symptoms declined significantly 48 hours after administration of the second dose compared to the first dose. The Chi-square test and multiple logistics regression results were consistent in demonstrating that younger vaccine recipients were more likely to report fever, body pain, chills, nausea, myalgia, headache, fatigue and other symptoms compared to older vaccine recipients. The multiple logistics regression indicate that female vaccine recipients had greater odds of reporting headache, fatigue, discomfort and less likely to report no symptoms compared to male vaccine recipients, 48 hours after receiving both doses. Conclusions: The findings indicate that on average, vaccine recipients reported fewer number of local and systemic side effects within 48 hours after receiving the second dose compared to 48 hours after receiving the first dose. The findings have implications on public health policy efforts to lower vaccine hesitancy.

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Medha Mathur ◽  
Navgeet Mathur

Abstract Background After the launch of COVID-19 vaccine by the government of India in 2021, the current study was conducted to assess the vaccine hesitancy among health care workers regarding COVID-19 vaccination and its safety, efficacy, rolling out strategy and undesirable effects. Methods This cross-sectional study, conducted on health care workers vaccinated at a tertiary care center of southern Rajasthan using a pre-designed and pre-validated questionnaire to collect data through the ‘Exit Interview’ technique after consent and ethical approval. Results Out of 3102, 56.8% were male and 43.2% were female health care workers. Out of total 80.7% and 73.2% of study participants perceived the vaccine as safe and effective respectively. The vaccine hesitancy was contributed due to apprehension for undesirable effects following immunization (19.3%). The commonest undesirable effect was pain at the injection site. The perception regarding the timing of rolling out of vaccine and readiness for COVID appropriate behavior after vaccination was significant (p < 0.001). The mean time spent at vaccination site was 33.90 (±11.34) minutes ranging 5-120 minutes (median = 35; interquartile range (IQR) = 10; 95% confidence interval (CI) = 33.50-34.30). Conclusions The study concludes that the apprehension of undesirable effects contributed to vaccine hesitancy, but it was perceived safe and effective by health care workers. Key messages The vaccine hesitancy among general population and vaccine acceptance will be affected directly by instance shown by health care workers who presented themselves at the forefront both for battling the pandemic and accepting the vaccine.


Author(s):  
Rajni Rai ◽  
Sonia El-Zaemey ◽  
Nidup Dorji ◽  
Lin Fritschi

Background: Collection of reliable and valid occupational history data is of utmost importanceto assess work-related exposures and their health effects. Few standardized questionnairesare available for the collection of occupational history data in low-and-middle incomecountries. Objective: To adapt and test a validated questionnaire developed in the United States by theNational Institute of Safety and Health, in order to assess occupational chemical exposuresamong health care workers in Bhutan. Methods: The questionnaire was first adapted to suit the Bhutanese context with the adviceof an expert review committee. 30 health care workers then completed the questionnaire atbaseline and 10–14 days later. Test-retest reliability was assessed by calculating Cohen's κand percentage agreement. Results: The questionnaire had high test-retest reliability. Cohen's κ ranged from 0.61 to1.00, and percentage agreement ranged from 86.7% to 100%. Further adaptations includedomitting questions on chemicals not available in Bhutan. Conclusion: The adapted questionnaire is appropriate for assessing occupational chemicalexposures among health care workers in Bhutan.


Author(s):  
Anja Bauer ◽  
Daniel Tiefengraber ◽  
Ursula Wiedermann

SummaryIn Austria, data on vaccine hesitancy is scarce. Available studies suggest around 1-11% of parents refuse vaccination, while many more are hesitant and consider refraining from some but not all of the recommended vaccinations. However, the key drivers for vaccine hesitancy in Austria are largely unknown. To learn more about vaccination coverage, attitude towards and knowledge around immunization as well as views on mandatory vaccination, we conducted a survey in a rural Austrian lay population including adults and children. Two paper-based questionnaires, one for adults 16 years or older and one for children aged 6-15 years, were developed, then sent to all houses of a rural community in Austria as well as handed out at the local primary and middle school, respectively. Self-reported coverage rates of children and adults were found to be low. Within the surveyed population 3% of children had never been or do not get vaccinated. More than half (57%) of the survey participants had a positive attitude towards vaccines, 21% were without reserves, 16% were found skeptical and 5% had a generally negative attitude. Knowledge about immunization in general was poor. Younger adults and people with secondary education appear to be most skeptical and negative towards vaccination. Children’s attitudes were closely linked to those of their parents. The major concern around vaccination in adults was fear of side effects. In adults, 54.2% support mandatory vaccination for Health Care Workers and 20.7% are against it. 39% of adults and 37% of children wanted more information on vaccination, preferably provided by physicians. Knowledge about disease prevention by vaccination should be improved and children could also benefit from an early age-appropriate vaccine education to strengthen health literacy. Physicians are the most trusted source of health information. Medical doctors should be aware of their very important role in transmitting trusted health information. This should include an up-to-date education in communicable disease prevention and immunization during their whole medical career. Furthermore, the curricula of health-care workers may need to be improved and harmonized concerning prevention and vaccination.


2020 ◽  
pp. 105215
Author(s):  
Victor Grech ◽  
Michael Borg ◽  
Charmaine Gauci ◽  
Christopher Barbara ◽  
Simon Attard-Montalto ◽  
...  

2021 ◽  
Vol 42 (6) ◽  
pp. 445-452
Author(s):  
Rajesh Kumar ◽  
Kalpana Beniwal ◽  
Yogesh Bahurupi ◽  
Ravi Kant ◽  
Mukesh Bairwa

Background: The coronavirus disease 2019 (COVID-19) pandemic has caused a large number of deaths along with severe socio-economic effects. The vaccine is considered to be the last hope to control viral transmission. This study aimed to explore the determinants of health care workers’ (HCWs) willingness to take the COVID-19 vaccination.Methods: A structured, pre-validated, and pre-tested questionnaire was administered online to 599 HCWs including physicians, residents, and nurses from different types of healthcare set-ups across India. Information was collected regarding vaccine acceptability, attitude toward vaccination, and reasons for hesitancy. The chi-square test, followed by multinomial regression analysis, was applied to determine the factors associated with HCWs’ vaccination willingness.Results: It was found that 73 % (n=437) of HCWs were willing to accept the vaccines, while 10.85% (n=65) refused and 16.2% (n=96) needed more time to decide. Gender (P<0.001), occupation (P=0.040), working as front-line workers (P=0.008), vaccine manufacturing country preferences (P<0.001), and perceived risk of catching COVID-19 in the next 6 months (P=0.005) had a significant association with intent to receive vaccination (the response were “yes” vs. “no” and “not sure”). The reasons for vaccine hesitancy were vaccine safety and efficacy concerns, antivaccine attitude and beliefs, personal choice, and not wanting to take a vaccine before others.Conclusion: The majority of HCWs agreed to take COVID-19 vaccines once available. Nevertheless, providing support to manage evolving vaccine environments will help change the perception of HCWs who refuse or are reluctant to take the vaccines.


2021 ◽  
Author(s):  
Martin Wiredu Agyekum ◽  
Grace Frempong Afrifa-Anane ◽  
Frank Kyei-Arthur ◽  
Bright Addo

The acceptance or otherwise of the COVID-19 vaccine by health care workers can influence the uptake of COVID-19 vaccines among the general population as they are a reliable source of health information. In this study, we sought to determine the acceptability of COVID-19 vaccines among health care workers in Ghana. Using a cross-sectional design, we collected data from 234 health care workers through a self-administered online survey from 16 January to 15 February 2021. Descriptive, bivariate and multivariate analyses using binary logistic regression were performed using STATA version 15. The results showed that 39.3% of health care workers had the intention of receiving the COVID-19 vaccine. Factors such as sex, category of health care workers, relative being diagnosed with COVID-19, and trust in the accuracy of the measures taken by the government in the fight against COVID-19 proved to be significant predictors of the acceptability of the COVID-19 vaccine. Concerns about the safety of vaccines and the adverse side effects of the vaccine were identified as the main reasons why health care workers would decline uptake of the COVID-19 vaccine in Ghana. The self-reported low intention of health care workers to accept the COVID-19 vaccine in Ghana requires the urgent call of the Government of Ghana and other stakeholders to critically address health care workers' concerns about the safety and adverse side effects of COVID-19 vaccines, as this would increase vaccine uptake. Interventions must also take into consideration sex and the category of health care workers to achieve the desired results. Keywords: COVID-19, Vaccines, Vaccine acceptance, Health care workers, Ghana


Author(s):  
Hari Kishan Boorugu ◽  
Krushna Chandra Misra ◽  
B. Saroj Kumar Prusty

Background: SARS-CoV-2 pandemic has affected the whole world and India is one among the most affected countries. Vaccination is the most important tool to halt this pandemic and vaccine hesitancy unfortunately derails vaccination drive. Vaccine hesitancy among people is mainly due to concerns about vaccine safety! This study was done to assess adverse effects of Covishield vaccine among health care workers in a single health care organization.Methods: All the vaccine recipients were requested to answer a questionnaire with demographic details and various side effects following both the doses of Covishield vaccination.Results: About 665 employees responded to the questionnaire and the most common adverse reaction following Covishield vaccine was injection site pain, which was reported by 63% of vaccinees after first dose of vaccine.Conclusions: Covishield vaccine is relatively safe and incidence of major adverse events are rare following vaccination.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Martin Wiredu Agyekum ◽  
Grace Frempong Afrifa-Anane ◽  
Frank Kyei-Arthur ◽  
Bright Addo

Because health care workers are a reliable source of health information, their acceptance or rejection of COVID-19 vaccines can influence the general population's uptake of COVID-19 vaccines. In this study, we sought to determine the acceptability of COVID-19 vaccines among health care workers in Ghana. Using a cross-sectional design, we collected data from 234 health care workers through a self-administered online survey from 16 January to 15 February 2021. Descriptive, bivariate, and multivariate analyses were performed using STATA version 15. The findings revealed that 39.3% (n = 92) of health care workers intended to receive the COVID-19 vaccines. Factors such as sex (AOR = 0.451; CI 95% 0.240–0.845; p = 0.013 ), category of health care workers (AOR = 2.851; 95 CI%: 1.097–7.405; p = 0.031 ), relative being diagnosed with COVID-19 (AOR = 0.369; CI 95% 0.145–0.941; p = 0.037 ), and trust in the accuracy of the measures taken by the government in the fight against COVID-19 (AOR = 2.768; CI 95%: 1.365–5.616; p = 0.005 ) proved to be significant predictors of the acceptability of the COVID-19 vaccine. Concerns about the safety of vaccines (n = 93, 65.5%) and the adverse side effects of the vaccines (n = 23, 14.8%) were identified as the main reasons why health care workers would decline uptake of COVID-19 vaccines in Ghana. The self-reported low intention of health care workers in Ghana to accept COVID-19 vaccines necessitates an urgent call from the Government of Ghana and other stakeholders to address health care workers' concerns about the safety and adverse side effects of COVID-19 vaccines, as this would increase vaccine uptake. Interventions must also take into consideration sex and the category of health care workers to achieve the desired results.


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