scholarly journals Out with the old and in with the new: The role of intolerance of uncertainty in reversal of threat and safety

2018 ◽  
Author(s):  
Jayne Morriss ◽  
Francesco Saldarini ◽  
Catherine Chapman ◽  
Miriam Pollard ◽  
Carien M. van Reekum
Keyword(s):  
Anxiety Disorders ◽  
Associative Learning ◽  
Trait Anxiety ◽  
Skin Conductance ◽  
Clinical Intervention ◽  
Intolerance Of Uncertainty ◽  
Shared Variance ◽  
Healthy Participants ◽  
Direct Threat

AbstractThe ability to learn and reverse threat associations is crucial for survival. The extent to which old threat associations are inhibited and new threat associations are formed may depend on sensitivity to future threat uncertainty. To assess the extent to which Intolerance of Uncertainty (IU) predicts threat learning and reversal, we recorded expectancy ratings and skin conductance in 44 healthy participants during an associative learning paradigm, where threat and safety contingencies were reversed. During acquisition and reversal, we observed larger SCR magnitude and expectancy ratings for threat vs. safety cues. However, during reversal higher IU was associated with larger SCR magnitude to new threat vs. new safety cues, compared to lower IU. These results were specific to IU-related variance, over shared variance with trait anxiety (STAIX-2). Overall, these findings suggest that individuals high in IU are able to reverse threat and safety associations in the presence of direct threat. Such findings help us understand the recently revealed link between IU and threat extinction, where direct threat is absent. Moreover, these findings highlight the potential relevance of IU in clinical intervention and treatment for anxiety disorders.

scholarly journals Out with the old and in with the new: The role of intolerance of uncertainty in reversal of threat and safety

2019 ◽  
Vol 10 (1) ◽  
pp. 204380871983445 ◽  
Author(s):  
Jayne Morriss ◽  
Francesco Saldarini ◽  
Catherine Chapman ◽  
Miriam Pollard ◽  
Carien M. van Reekum
Keyword(s):  
Trait Anxiety ◽  
Skin Conductance ◽  
Skin Conductance Response ◽  
Clinical Intervention ◽  
Intolerance Of Uncertainty ◽  
Anxiety State ◽  
Extinction Learning ◽  
Healthy Participants ◽  
Direct Threat

Intolerance of uncertainty (IU) is associated with difficulty in updating contingencies from threatening to safe during extinction learning. However, it is unknown whether high IU individuals have difficulty (1) generally with updating threat to safe associations when contingencies change or (2) specifically with updating threat to safe associations during extinction learning, where direct threat is omitted. To address this question, we recorded IU, expectancy ratings, and skin conductance in 44 healthy participants during an associative learning paradigm, where threat and safety contingencies were reversed. During acquisition and reversal, we observed larger skin conductance response (SCR) magnitude and expectancy ratings for threat versus safety cues. However, during reversal, higher IU was associated with larger SCR magnitude to new threat versus new safety cues, compared with lower IU. These results were specific to IU-related variance, over shared variance with trait anxiety (State-Trait Anxiety Inventory, Trait Version). Overall, these findings suggest that individuals high in IU are able to reverse threat and safety associations in the presence of direct threat. Such findings help us understand the recently revealed link between IU and threat extinction, where direct threat is absent. Moreover, these findings highlight the potential relevance of IU in clinical intervention and treatment for anxiety disorders.

scholarly journals What do I do now? Intolerance of uncertainty is associated with discrete patterns of anticipatory physiological responding to different uncertain contexts

2019 ◽  
Author(s):  
Jayne Morriss
Keyword(s):  
Decision Making ◽  
Trait Anxiety ◽  
Skin Conductance ◽  
Physiological Responses ◽  
Reaction Times ◽  
Intolerance Of Uncertainty ◽  
Physiological Measures ◽  
Corrugator Supercilii ◽  
The Relationship

AbstractHeightened physiological responses to uncertainty are a common hallmark of anxiety disorders. Many separate studies have examined the relationship between individual differences in intolerance of uncertainty (IU) and physiological responses to uncertainty during different contexts. Despite this, little is known about the extent to which physiological responses during different uncertain contexts covary within individuals based on IU. Anticipatory physiological responses to uncertainty were assessed in three different contexts (associative threat learning, basic threat uncertainty, decision-making) within the same sample (n = 45). During these tasks, behavioural responses (i.e. reaction times, choices), skin conductance and corrugator supercilli activity were recorded. In addition, self-reported IU and trait anxiety were measured. IU made different contributions to the physiological measures during each task. IU was found to modulate both skin conductance and corrugator supercilii activity for the associative threat learning and decision-making contexts. However, trait anxiety was found to modulate corrugator supercilii activity during the basic threat uncertainty context. Ultimately, this research helps us further tease apart the role of IU in different uncertain contexts, which will be relevant for future IU-related models of psychopathology.

The role of personality traits in initiating and maintaining addictive behavior

2016 ◽  
Vol 33 (S1) ◽  
pp. S307-S307
Author(s):  
M. Manea ◽  
B. Savu
Keyword(s):  
Substance Abuse ◽  
Anxiety Disorders ◽  
Personality Traits ◽  
Trait Anxiety ◽  
Psychiatric Clinic ◽  
Strongly Correlated ◽  
Addictive Disorder ◽  
Substance Disorders ◽  
Competing Interest

IntroductionIt is well known that certain personality traits are more linked to drug abuse than others. Psychiatrists are more likely to emphasize the importance of impulsivity in the connection with substance disorders but in the following study we found an important percentage of patients that have a substance abuse were linked to anxiety through impulsiveness as a personality trait.ObjectivesMost youths admitted for a substance abuse are highly impulsive. Our quest was to differentiate what component of impulsivity was more frequently linked to a substance use disorder.MethodsIn the study were included 50 patients admitted in the 3rd Psychiatric Clinic, Substance Dependences Department, Cluj-Napoca. For the identification of the drug abused we used the multitest screening kit in correlation with the results from the Forensic Medicine Institute of Cluj-Napoca. Each patient completed the Barratt Impulsivity Scale and the Swedish Universities Scales of Personality.ResultsHigh scores on BIS-11 strongly correlated with attentional impulsiveness (Pearson's r correlation = .838) which means high inattention and cognitive instability this being linked with anxiety disorders. Cognitive Instability was correlated with Psychic Trait Anxiety (r = 0.29) and Motor Impulsiveness with Somatic Trait Anxiety (r = 0.3). Normal 0 false false false EN-US X-NONE X-NONE.ConclusionsThe underrecognized anxiety disorders in young adults whom are admitted for an addictive disorder prefrontal cortex is known to be the source of both impulsivity and could be linked to anxiety as well (valence asymmetry hypothesis). Normal 0 false false false EN-US X-NONE X-NONE.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The role of intolerance of uncertainty in the acquisition and extinction of reward

2020 ◽  
Author(s):  
Jayne Morriss ◽  
Nicolo Biagi ◽  
Tina B. Lonsdorf ◽  
Marta Andreatta
Keyword(s):  
Associative Learning ◽  
Conceptual Understanding ◽  
Skin Conductance Response ◽  
Intolerance Of Uncertainty ◽  
Acquisition Training ◽  
Learning Task ◽  
Partial Reward ◽  
Extinction Training ◽  
Corrugator Supercilii

AbstractIndividuals, who score high in self-reported intolerance of uncertainty (IU), tend to find uncertainty anxiety-provoking. IU has been reliably associated with disrupted threat extinction. However, it remains unclear whether IU would be related to disrupted extinction to other arousing stimuli that are not threatening (i.e., rewarding). We addressed this question by conducting a reward associative learning task with acquisition and extinction training phases (n = 58). Throughout the associative learning task, we recorded valence ratings (i.e. liking), skin conductance response (SCR) (i.e. sweating), and corrugator supercilii activity (i.e. brow muscle indicative or negative and positive affect) to learned reward and neutral cues. During acquisition training with partial reward reinforcement, higher IU was associated with greater corrugator supercilii activity to neutral compared to reward cues. IU was not related to valence ratings or SCR’s during the acquisition or extinction training phases. These preliminary results suggest that IU-related deficits during extinction may be limited to situations with threat. The findings further our conceptual understanding of IU’s role in the associative learning and extinction of reward, and in relation to the processing of threat and reward more generally.

scholarly journals Effects of intolerance of uncertainty on subjective and psychophysiological measures during fear acquisition and delayed extinction

2021 ◽  
Author(s):  
Maren Klingelhöfer-Jens ◽  
Jayne Morriss ◽  
Tina B Lonsdorf
Keyword(s):  
Fear Conditioning ◽  
Skin Conductance ◽  
Intolerance Of Uncertainty ◽  
Acquisition Training ◽  
Extinction Training ◽  
Future Directions ◽  
Psychophysiological Measures ◽  
Learned Fear ◽  
Startle Blink

Individuals who score high in self-reported Intolerance of Uncertainty (IU) tend to find uncertainty unacceptable and aversive. In recent years, research has shed light on the role of IU in modulating subjective (i.e. expectancy ratings) and psychophysiological responses (i.e. skin conductance) across different classical fear conditioning procedures, particularly that of immediate extinction. However, there remain gaps in understanding how IU, in comparison to other negative emotionality traits (STAI-T), impact different types of subjective and psychophysiological measures during different classical fear conditioning procedures. Here, we analyzed IU, STAI-T, subjective (i.e. fear ratings) and psychophysiological (i.e. skin conductance, auditory startle blink) data recorded during fear acquisition training and 24h-delayed extinction training (n = 66). Higher IU, over STAI-T, was: (1) significantly associated with greater fear ratings to the learned fear cue during fear acquisition training, and (2) at trend associated with greater fear ratings to the learned fear versus safe cue during delayed extinction training. Both IU and STAI-T were not related to skin conductance or auditory startle blink during fear acquisition training and delayed extinction training. These results add to and extend our current understanding of the role of IU on subjective and physiological measures during different fear conditioning procedures, particularly that of delayed extinction training. Implications of these findings and future directions are discussed.

scholarly journals The role of trait anxiety in associative learning during and after an aversive event

2019 ◽  
Vol 26 (2) ◽  
pp. 56-59 ◽  
Author(s):  
Arne Ilse ◽  
Virginia Prameswari ◽  
Evelyn Kahl ◽  
Markus Fendt
Keyword(s):  
Associative Learning ◽  
Trait Anxiety ◽  
Aversive Event

scholarly journals I doubt it is safe: A meta-analysis of self-reported intolerance of uncertainty and threat extinction training

2021 ◽  
Author(s):  
Jayne Morriss ◽  
Shannon Jade Wake ◽  
Charlotte Elizabeth ◽  
Carien M. van Reekum
Keyword(s):  
Trait Anxiety ◽  
Skin Conductance ◽  
Skin Conductance Response ◽  
Meta Analysis ◽  
Intolerance Of Uncertainty ◽  
Mental Health Disorders ◽  
Extinction Training ◽  
The Self ◽  
Target Uncertainty ◽  
Health Disorders

Intolerance of uncertainty (IU), the tendency to find uncertainty distressing, is an important transdiagnostic dimension in mental health disorders. Higher self-reported IU has been linked to poorer threat extinction training (i.e., the updating of threat to safe associations), a key process that is targeted in exposure-based therapies. However, it remains to be seen whether IU-related effects during threat extinction training are reliably and specifically driven by the IU construct or a particular subcomponent of the IU construct over other self-reported measures of anxiety. A meta-analysis of studies from different laboratories (experiment n = 18; sample n = 1006) was conducted on associations between different variants of self-reported IU (i.e., 27-item, 12-item, inhibitory and prospective subscales), trait anxiety and threat extinction training via skin conductance response. The specificity of IU and threat extinction training was assessed against measures of trait anxiety. All of the self-reported variants of IU, but not trait anxiety, were associated with threat extinction training via skin conductance response (i.e., continued responding to the old threat cue). Specificity was observed for the majority of self-reported variants of IU over of trait anxiety. The findings suggest that the IU construct broadly accounts for difficulties in threat extinction training and is specific over other measures of self-reported anxiety. These findings demonstrate the robustness and specificity of IU-related effects during threat extinction training and highlight potential opportunities for translational work to target uncertainty in therapies that rely on threat extinction principles such as exposure therapy.

scholarly journals An Exploration of the Mechanism of Action of an Equine-Assisted Intervention

Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 303 ◽  
Author(s):  
Ann Hemingway ◽  
Sid Carter ◽  
Andrew Callaway ◽  
Emma Kavanagh ◽  
Shelley Ellis
Keyword(s):  
Skin Conductance ◽  
Mechanism Of Action ◽  
Mixed Method ◽  
Temporal Change ◽  
Skin Conductance Responses ◽  
Equine Assisted ◽  
Emotional Landscape ◽  
Method Approach ◽  
Healthy Participants

Though long alluded to, there is now an accumulation of evidence of the vital contribution that emotion makes to learning. Within this broad advance in understanding is a growing body of research emphasising the embodied nature of this emotion-based learning. The study presented here is a pilot study using a mixed-method approach (combining both physiological and experiential methodologies) to give a picture of the “emotional landscape” of people’s learning through the intervention under study. This has allowed researchers to examine mediating pathways that may underlie any effects of an equine-assisted intervention. This study specifically focuses on examining the role of emotion. The intervention under study was used with young people with chronic mental health and behavioural problems for whom talk-based interventions were not working. Nine healthy participants aged 18–24 undertook the equine intervention, with an initial group having emotion-related psycho-physiological changes (skin conductance responses) measured while viewing their experience on video, and a further two participants experiencing a development of the methodology as their physiological responses were captured in real time during the intervention. The sessions were analysed by a group of five cross-disciplinary researchers to determine when significant learning episodes occurred, and the findings were that this learning was associated with powerful skin conductance responses. The qualitative element of the research entailed the participants watching themselves on video undertaking the equine intervention. They were asked to stop the video and share any changes in emotion at any point while watching. All participants experienced a positive temporal change in mood as the intervention progressed. All results supported the findings that emotional arousal occurred in relation to the participants asking the horse to perform a task. This paper will offer two novel contributions: (1) description of a new methodology for investigating the mechanism of action occurring in this type of intervention and (2) findings from the exploration of the intervention via psycho-physiological and experiential mechanisms.

IT’S NOT WHAT IT SEEMS! THE MEDIATING ROLE OF SELF-EFFICACY IN THE RELATIONSHIP BETWEEN TRAIT-ANXIETY AND INTOLERANCE OF UNCERTAINTY DURING COVID-19 PANDEMIC

2021 ◽  
Vol 14(63) (1) ◽  
pp. 27-36
Author(s):  
Livia ȚÂNCULESCU-POPA ◽  
Keyword(s):  
Trait Anxiety ◽  
Self Efficacy ◽  
Intolerance Of Uncertainty ◽  
Mediating Role ◽  
The Impact ◽  
The Relationship ◽  
General Self Efficacy

The current research is aimed at studying the relationship between trait anxiety and intolerance of uncertainty, with its both facets: the inhibitory and the prospective anxiety and to establish whether or not the general self-efficacy plays a mediating role between the trait-anxiety and intolerance of uncertainty. Results show that a partial mediation takes part when general self-efficacy mediates the relationship between the intolerance of uncertainty, inhibitory anxiety, but a limited mediation when general selfefficacy interferes in the relationship between the trait-anxiety and intolerance of uncertainty, perspective anxiety. The main benefit of this paper is to demystify the impact of self-efficacy especially in unexpected, unknown situations, such as the COVID-19 pandemic.

A review of the relationship between intolerance of uncertainty and threat appraisal in anxiety

2019 ◽  
Vol 12 ◽  
Author(s):  
S. Milne ◽  
C. Lomax ◽  
M. H. Freeston
Keyword(s):  
Anxiety Disorders ◽  
Cognitive Biases ◽  
Cognitive Model ◽  
Intolerance Of Uncertainty ◽  
Future Research ◽  
Threat Appraisal ◽  
List Type ◽  
Relationship Of ◽  
Conceptual Foundations

Abstract The development and conceptual relationship of the constructs of threat appraisal (TA) and intolerance of uncertainty (IU) are explored in the context of anxiety disorders. A narrative review tracking the development of these constructs and their relationship is undertaken. There is some evidence to suggest that the interaction between the components of threat appraisal (probability × cost) may partially account for or provide a theoretical framework which explains presenting levels of anxiety. Furthermore, research suggested that IU is a construct which contributes to a broad range of anxiety disorders. It was concluded that distinctive cognitive biases linked with IU – such as interpreting ambiguous and uncertain (both positive and negative) information as highly concerning – suggests that IU is interpreted negatively independent of threat appraisal. These findings mean a number of issues remain unclear, including whether IU in anxiety-provoking situations is sufficient in itself – independent of threat appraisal – in eliciting high levels of anxiety. Additionally, it is unclear whether threat appraisal and IU act as independent constructs, or more in an interactive manner in anxiety. To achieve further clarity on these issues, methodological recommendations for future research are made. Key learning aims (1) To understand the conceptual foundations of TA and IU in the cognitive model of anxiety. (2) To understand the empirical evidence supporting the role of both TA and IU in anxiety. (3) To appreciate the potential relationship between these concepts in anxiety.

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