scholarly journals The role of hydrogen bonding in the incommensurate modulation of myo-inositol camphor ketal

2021 ◽  
Vol 77 (1) ◽  
pp. 83-92
Author(s):  
Viktor Savic ◽  
Felix Eder ◽  
Christian Göb ◽  
Marko D. Mihovilovic ◽  
Christian Stanetty ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Basic Structure ◽  
Two Dimensions ◽  
Group Symmetry ◽  
Internal Space ◽  
Disorder Phase Transition ◽  
Modulation Wave ◽  
Incommensurate Structure ◽  
Incommensurate Modulation ◽  
Definition Of

myo-Inositol-2,3-D-camphor ketal crystallizes as an incommensurate structure with the C2(0σ2½) superspace group symmetry [σ2 = 0.1486 (3) at 100 K]. The bornane and myo-inositol moieties aggregate in distinct layers extending parallel to (001). The myo-inositol rings are connected by a complex hydrogen-bonding network extending in two dimensions, which is disordered in the basic structure and (mostly) ordered in the actual modulated structure. The domains of definition of the H atoms in internal space were derived by chemical reasoning and modeled with crenel functions. By tracing the hydrogen bonding, distinct chains, which are periodic in the [100] direction, are identified. These chains possess one of two possible orientations with respect to the hydrogen bonding. The incommensurate modulation is characterized by a non-periodic succession of the two chain orientations in the [010] direction. On heating, the σ2-component of the modulation wave vector decreases from σ2 = 0.1486 (3) at 100 K to σ2 = 0.1405 (6) at 430 K, which means that the periodicity of the modulation wave increases. No order–disorder phase transition was evidenced up to the melting point (with decomposition).

scholarly journals A FUZZY FRONT-END PRODUCT DEVELOPMENT FRAMEWORK FOR START-UPS

2021 ◽  
Vol 1 ◽  
pp. 111-120
Author(s):  
Nuno Miguel Martins Pacheco ◽  
Anand Vazhapilli Sureshbabu ◽  
Masaru Charles Nürnberger ◽  
Laura Isabel Durán Noy ◽  
Markus Zimmermann
Keyword(s):  
Two Dimensions ◽  
Fuzzy Front End ◽  
Development Framework ◽  
Front End ◽  
Start Up ◽  
Extended Approach ◽  
Role Based ◽  
Definition Of ◽  
Clear Idea ◽  
Start Ups

AbstractStart-ups tend to form with a central idea that differentiates them from their competitors in the market. It is crucial for them to efficiently transform the idea into a marketable product. Prototyping helps to iteratively achieve a minimum viable product and plays a crucial role by enabling teams to test their ideas with limited resources early on. However, the prototyping process may have wrong focus leading to a suboptimal allocation of resources. Previously, we proposed role-based prototyping for fuzzy front-end development in small teams. It supports (1) resource allocation, (2) the definition of responsibilities, and (3) structuring the development process with milestones. In recent research this was a promising yet incomplete approach. We extend the previous work by refining the prototyping process by adding a prototyping matrix with two dimensions (purpose and lens), a prototyping cycle (plan, execute, test, reflect, assimilate), and a modified Kanban board (Protoban) for planning, managing, and reflecting cycles. This process, named PETRA was tested with a start-up developing an autonomous trash picking robot. The extended approach supported the team significantly in providing a clear idea of what to do at what time.

scholarly journals Three-dimensional quantification of twisting in the Arabidopsis petiole

2021 ◽  
Author(s):  
Yuta Otsuka ◽  
Hirokazu Tsukaya
Keyword(s):  
Cross Sections ◽  
Three Dimensional ◽  
Light Sheet ◽  
Underlying Mechanism ◽  
Two Dimensions ◽  
Observation Angle ◽  
Differential Growth ◽  
Light Sheet Microscopy ◽  
Definition Of ◽  
Twisting Angle

AbstractOrganisms have a variety of three-dimensional (3D) structures that change over time. These changes include twisting, which is 3D deformation that cannot happen in two dimensions. Twisting is linked to important adaptive functions of organs, such as adjusting the orientation of leaves and flowers in plants to align with environmental stimuli (e.g. light, gravity). Despite its importance, the underlying mechanism for twisting remains to be determined, partly because there is no rigorous method for quantifying the twisting of plant organs. Conventional studies have relied on approximate measurements of the twisting angle in 2D, with arbitrary choices of observation angle. Here, we present the first rigorous quantification of the 3D twisting angles of Arabidopsis petioles based on light sheet microscopy. Mathematical separation of bending and twisting with strict definition of petiole cross-sections were implemented; differences in the spatial distribution of bending and twisting were detected via the quantification of angles along the petiole. Based on the measured values, we discuss that minute degrees of differential growth can result in pronounced twisting in petioles.

Footpaths of the Late-Soviet Environmental Turn: The “Forest City” of Novosibirsk’s Akademgorodok as a Sociotechnical Imaginary

2021 ◽  
Vol 48 (3) ◽  
pp. 289-313
Author(s):  
Roman Bugaev ◽  
Mikhail Piskunov ◽  
Timofey Rakov
Keyword(s):  
Soviet Union ◽  
Two Dimensions ◽  
Visual Perspective ◽  
Garden City ◽  
Soviet Science ◽  
Definition Of ◽  
Green Ideas ◽  
Human Flora ◽  
The Relationship ◽  
The City

Abstract The founding of Akademgorodok near Novosibirsk in the late 1950s features prominently in the historiography of the Thaw and the general turn of Soviet science to the eastern parts of the country. This article puts this story into the context of the formation of modern “green” ideas in the late Soviet Union and reconsiders the relationship between humans and nature, along with the definition of nature itself. Akademgorodok produced a telling visual perspective: the architectural plan for the city dictated that its scientific, industrial, and living zones were drowned deep in the taiga. Architects named this type of urban planning “diffusive,” and memoirists described it as a “Forest City.” Using the term of Sheila Jasanoff, we designate this “Forest City” as a sociotechnical imaginary of Akademgorodok. Our aim is to study the historical roots of the “Forest City” and how it became a collective imaginary. How did it happen that in the 1950s and 1960s, when the “faces” of Soviet cities were defined by districts of standard panel houses, that a city was built near Novosibirsk in which so much attention was given to pre-human flora, fauna, and landscapes? What ideas and intellectual contexts composed the concept of Akademgorodok as a “Forest City”? Our answer possesses two dimensions. First, the rejection of the use of decorative elements in housing construction in the post-Stalin epoch stimulated architects to pay more attention to the greening of cities. They revived the concept of a “garden city” proposed by Ebenezer Howard on a new level. Second, the evolution of the ideas of Mikhail Lavrentyev, the founder of Akademgorodok, who upon arrival in Siberia applied the productivist program manifested in the slogan “Siberia is a treasure of resources,” but later changed his opinion to more “green” views under the influence of the so-called “Baikal Discussion.” The viewpoints of Lavrentyev influenced the design of this “center” of Siberian science, and then he formulated the idea of a “Forest City.” These contexts enable the utopian horizons and the search for models of a constructed future that were typical of the Thaw era to reflect upon the important challenges of the contemporary Anthropocene.

The basic structure, typology, functions, revenues and expenditure of the tertiary sector in the U.S.

2021 ◽  
pp. 99
Author(s):  
Alexey Shlihter
Keyword(s):  
Public Goods ◽  
Basic Structure ◽  
The State ◽  
Tertiary Sector ◽  
Definition Of ◽  
Local Levels ◽  
The U.S ◽  
Self Organizing

The article attempts to present the multifaceted world of the American tertiary sector; explains the need for using non-market instruments in order to provide public goods; clarifies relations and connections of the tertiary sector organizations with the state and business. The definition of the tertiary sector as forming a horizontal multidimensional, multi-vector, growing and self-organizing system of naturally developing relations between people is given. The system is seen as a collection of communities emerging and functioning at the national and local levels, with one of their main tasks being to provide people with the opportunity to communicate and make important decisions, based on similar practical and spiritual interests.

scholarly journals Psychological autonomy and hierarchical relatedness as organizers of developmental pathways

2016 ◽  
Vol 371 (1686) ◽  
pp. 20150070 ◽  
Author(s):  
Heidi Keller
Keyword(s):  
Two Dimensions ◽  
Global Perspective ◽  
Developmental Pathways ◽  
Cultural Constructs ◽  
Human Needs ◽  
Subsistence Farmer ◽  
The Hierarchical Structure ◽  
Psychological Autonomy ◽  
The One ◽  
Definition Of

The definition of self and others can be regarded as embodying the two dimensions of autonomy and relatedness. Autonomy and relatedness are two basic human needs and cultural constructs at the same time. This implies that they may be differently defined yet remain equally important. The respective understanding of autonomy and relatedness is socialized during the everyday experiences of daily life routines from birth on. In this paper, two developmental pathways are portrayed that emphasize different conceptions of autonomy and relatedness that are adaptive in two different environmental contexts with very different affordances and constraints. Western middle-class children are socialized towards psychological autonomy, i.e. the primacy of own intentions, wishes, individual preferences and emotions affording a definition of relatedness as psychological negotiable construct. Non-Western subsistence farmer children are socialized towards hierarchical relatedness, i.e. positioning oneself into the hierarchical structure of a communal system affording a definition of autonomy as action oriented, based on responsibility and obligations. Infancy can be regarded as a cultural lens through which to study the different socialization agendas. Parenting strategies that aim at supporting these different socialization goals in German and Euro-American parents on the one hand and Nso farmers from North Western Cameroon on the other hand are described. It is concluded that different pathways need to be considered in order to understand human psychology from a global perspective.

CHAOTIC DYNAMICS FOR MAPS IN ONE AND TWO DIMENSIONS: A GEOMETRICAL METHOD AND APPLICATIONS TO ECONOMICS

2009 ◽  
Vol 19 (10) ◽  
pp. 3283-3309 ◽  
Author(s):  
ALFREDO MEDIO ◽  
MARINA PIREDDU ◽  
FABIO ZANOLIN
Keyword(s):  
Dynamical Systems ◽  
Discrete Time ◽  
Chaotic Dynamics ◽  
Economic Models ◽  
Two Dimensions ◽  
Geometrical Method ◽  
Mathematical Ideas ◽  
Definition Of ◽  
Applications To Economics ◽  
Discrete Time Dynamical Systems

This article describes a method — called here "the method of Stretching Along the Paths" (SAP) — to prove the existence of chaotic sets in discrete-time dynamical systems. The method of SAP, although mathematically rigorous, is based on some elementary geometrical considerations and is relatively easy to apply to models arising in applications. The paper provides a description of the basic mathematical ideas behind the method, as well as three applications to economic models. Incidentally, the paper also discusses some questions concerning the definition of chaos and some problems arising from economic models in which the dynamics are defined only implicitly.

scholarly journals Benchmarking the Extent and Speed of Reperfusion: First Pass TICI 2c-3 Is a Preferred Endovascular Reperfusion Endpoint

2021 ◽  
Vol 12 ◽  
Author(s):  
Albert J. Yoo ◽  
Jazba Soomro ◽  
Tommy Andersson ◽  
Jeffrey L. Saver ◽  
Marc Ribo ◽  
...  
Keyword(s):  
Functional Independence ◽  
Multicenter Trial ◽  
Two Dimensions ◽  
National Institutes Of Health ◽  
Clinical Trial Registration ◽  
Early Improvement ◽  
Attractive Candidate ◽  
First Pass ◽  
Definition Of ◽  
International Multicenter

Background and Purpose: End-of-procedure substantial reperfusion [modified Treatment in Cerebral Ischemia (mTICI) 2b-3], the leading endpoint for thrombectomy studies, has several limitations including a ceiling effect, with recent achieved rates of ~90%. We aimed to identify a more optimal definition of angiographic success along two dimensions: (1) the extent of tissue reperfusion, and (2) the speed of revascularization.Methods: Core-lab adjudicated TICI scores for the first three passes of EmboTrap and the final all-procedures result were analyzed in the ARISE II multicenter study. The clinical impact of extent of reperfusion and speed of reperfusion (first-pass vs. later-pass) were evaluated. Clinical outcomes included 90-day functional independence [modified Rankin Scale (mRS) 0–2], 90-day freedom-from-disability (mRS 0–1), and dramatic early improvement [24-h National Institutes of Health Stroke Scale (NIHSS) improvement ≥ 8 points].Results: Among 161 ARISE II subjects with ICA or MCA M1 occlusions, reperfusion results at procedure end showed substantial reperfusion in 149 (92.5%), excellent reperfusion in 121 (75.2%), and complete reperfusion in 79 (49.1%). Reperfusion rates on first pass were substantial in 81 (50.3%), excellent reperfusion in 62 (38.5%), and complete reperfusion in 44 (27.3%). First-pass excellent reperfusion (first-pass TICI 2c-3) had the greatest nominal predictive value for 90-day mRS 0–2 (sensitivity 58.5%, specificity 68.6%). There was a progressive worsening of outcomes with each additional pass required to achieve TICI 2c-3.Conclusions: First-pass excellent reperfusion (TICI 2c-3), reflecting rapid achievement of extensive reperfusion, is the technical revascularization endpoint that best predicted functional independence in this international multicenter trial and is an attractive candidate for a lead angiographic endpoint for future trials.Clinical Trial Registration:http://www.clinicaltrials.gov, identifier NCT02488915.

scholarly journals The crystal structure of cyanotrichite

2015 ◽  
Vol 79 (2) ◽  
pp. 321-335 ◽  
Author(s):  
Stuart J. Mills ◽  
Andrew G. Christy ◽  
Fernando Colombo ◽  
Jason R. Price
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonding ◽  
Local Structure ◽  
Unit Cell ◽  
Group Symmetry ◽  
Hydrogen Atoms ◽  
Unit Cell Parameters ◽  
Space Group ◽  
Cell Parameters ◽  
Bonding Scheme

AbstractWe report the single-crystal average structure of cyanotrichite, Cu4Al2[SO4](OH)12(H2O)2, from the Maid of Sunshine mine, Arizona, USA. Cyanotrichite crystallizes in space group C2/m, with the unit-cell parameters a = 12.625(3), b = 2.8950(6), c = 10.153(2) Å and β = 92.17(3)o. All non-hydrogen atoms were located and refined to R1 = 0.0394 for all 584 observed reflections [Fo > 4σFo] and 0.0424 for all 622 unique reflections. The cyanotrichite structure consists of a principal building unit of a three-wide [Cu2Al(OH)6] ribbon of edge-sharing Cu and Al polyhedra || b, similar to that found for camerolaite. The ribbons lie in layers || (001) and between these layers, while SO4 tetrahedra and H2O molecules form rods running || b. A hydrogen-bonding scheme is also proposed.A sample of cyanotrichite from the Cap Garonne mine, Le Pradet, France, showed a 4b superstructure with the following unit cell: space group P2/m, a = 12.611(2) Å, b = 11.584(16) = 4 × 2.896(4) Å, c = 10.190(1) Å and β = 92.29(6)o. The supercell could not be refined in detail, but nevertheless imposes constraints on the local structure in that while the space-group symmetry prevents full order of SO4 and H2O in the 4b supercell, it requires that the sequence of species along any given rod is [-SO4-SO4-(H2O)2-(H2O)2-] rather than [-SO4-(H2O)2-SO4-(H2O)2-].

scholarly journals Definitions and criteria: the 2007 amendments to the Mental Health Act 1983

2010 ◽  
Vol 16 (3) ◽  
pp. 161-167 ◽  
Author(s):  
Tim Branton ◽  
Guy Brookes
Keyword(s):  
Mental Health ◽  
Mental Disorder ◽  
Medical Treatment ◽  
Psychological Treatment ◽  
Basic Structure ◽  
Code Of Practice ◽  
Mental Health Act ◽  
Sexual Deviancy ◽  
Definition Of ◽  
Mental Capacity Act

SummaryThis article deals with the provisions for the lawful detention and compulsory treatment of patients in England and Wales. The 2007 amendments to the Mental Health Act 1983 redefine ‘mental disorder’ and ‘medical treatment’ and remove the classifications required for longer-term detention, abolishing the so-called ‘treatability test’ and introducing a new appropriate-treatment test. ‘Learning disability’ is brought within the definition of mental disorder but only if ‘associated with abnormally aggressive or seriously irresponsible conduct’. The exclusion for promiscuity, other immoral conduct or sexual deviancy is repealed; the exclusion for dependence on alcohol and drugs is retained. The revised definition of ‘medical treatment’ includes psychological treatment and removes the requirement that treatment is under medical supervision. The basic structure of the 1983 Act is retained. Use of the powers is discretionary. The principles of the Mental Capacity Act 2005 are imported into the decision-making framework through the wording of the Mental Health ActCode of Practice.

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