Photo-modulated optical and electrical properties of graphene

Photo-modulation is a promising strategy for contactless and ultrafast control of optical and electrical properties of photoactive materials. Graphene is an attractive candidate material for photo-modulation due to its extraordinary physical properties and its relevance to a wide range of devices, from photodetectors to energy converters. In this review, we survey different strategies for photo-modulation of electrical and optical properties of graphene, including photogating, generation of hot carriers, and thermo-optical effects. We briefly discuss the role of nanophotonic strategies to maximize these effects and highlight promising fields for application of these techniques.

Design of a 1×2 CPW Fractal Antenna Array on Plexiglas Substrate with Defected Ground Plane for Telecommunication Applications

In this paper, a fractal antenna array for telecommunication applications is presented. The proposed antenna array is realized on a Plexiglas substrate, has 1×2 radiating elements, and dimensions of 170mm×105mm. The antenna array is composed of two Koch Snowflake patches and is fed by a Coplanar Waveguide (CPW) transmission line. Radiating elements and the ground plane are printed on the top side of the substrate. Defected Ground Structure (DGS) technique is employed to enhance the bandwidth and improve the impedance matching. The proposed antenna array operates at two frequency bands, 1.08-1.32GHz covering the GPS band and 1.7-3.7GHz covering the GSM 1800/1900, UTMS, Bluetooth, LTE, and WiMAX bands. In addition, the antenna has a good performance with efficiency and peak gain of 82% and 6.3dB respectively. These characteristics allow the antenna to be an attractive candidate for telecommunication systems. Design and analysis of different structures were carried out with Ansys HFSS.

DNA Nanodevices: from Mechanical Motions to Biomedical Applications

: Inspired by molecular machines in nature, artificial nanodevices have been designed to realize various biomedical functions. Self-assembled deoxyribonucleic acid (DNA) nanostructures that feature designed geometries, excellent spatial accuracy, nanoscale addressability and marked biocompatibility provide an attractive candidate for constructing dynamic nanodevices with biomarker-targeting and stimuli-responsiveness for biomedical applications. Here, a summary of typical construction strategies of DNA nanodevices and their operating mechanisms are presented. We also introduced recent advances in employing DNA nanodevices as platforms for biosensing and intelligent drug delivery. Finally, the broad prospects and main challenges of the DNA nanodevices in biomedical applications are discussed.

Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System

Traditional Chinese medicine (TCM) has demonstrated superior therapeutic effect for musculoskeletal diseases for thousands of years. Recently, the herbal extracts of TCM have received rapid advances in musculoskeletal tissue engineering (MTE). A literature review collecting both English and Chinese references on bioactive herbal extracts of TCM in biomaterial-based approaches was performed. This review provides an up-to-date overview of application of TCMs in the field of MTE, involving regulation of multiple signaling pathways in osteogenesis, angiogenesis, anti-inflammation, and chondrogenesis. Meanwhile, we highlight the potential advantages of TCM, opening the possibility of its extensive application in MTE. Overall, the superiority of traditional Chinese medicine turns it into an attractive candidate for coupling with advanced additive manufacturing technology.

Thermal real scalar triplet dark matter

Real scalar triplet dark matter, which is known to be an attractive candidate for a thermal WIMP, is comprehensively studied paying particular attention to the Sommerfeld effect on the dark matter annihilation caused by the weak interaction and the other interaction between the dark matter and the Higgs boson. We find a parameter region that includes the so-called ‘WIMP-Miracle’ one is still surviving, i.e. it respects all constraints imposed by dark matter searches at collider experiments, underground experiments (direct detection) and astrophysical observations (indirect detection). The region is also found to be efficiently searched for by various near future experiments. In particular, the XENONnT experiment will cover almost the entire parameter region.

Enhanced One-Photon and Two-Photon Amplified Spontaneous Emissions of CsPbBr3 Thin Films by Insulating Polymer Coating

Lead halide perovskite is an attractive candidate for fabricating low-cost one-photon and two-photon-pumped lasers. However, the presence of vast trap sites and the leakage of electric fields limit the efficient amplified spontaneous emission (ASE) performances. Herein, we show that incorporating an insulating polymethylmethacrylate layer with a proper thickness onto perovskite films can play an important role in not only reducing both one-photon and two-photon ASE thresholds but also improving the light exposure stability remarkably. By means of spectroscopic investigation and optical simulation, the enhancement was ascribed to the trap passivation and electric field restraint and improved light outcoupling due to the dielectric confinement by the formation of symmetric waveguides structure. This work indicates the possibility of simple and effective approaches to realize efficient ASE and lasing.

Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection

The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates strategies to identify prophylactic and therapeutic drug candidates to enter rapid clinical development. This is particularly true, given the uncertainty about the endurance of the immune memory induced by both previous infections or vaccines, and given the fact that the eradication of SARS-CoV-2 might be challenging to reach, given the attack rate of the virus, which would require unusually high protection by a vaccine. Here, we show how raloxifene, a selective estrogen receptor modulator with anti-inflammatory and antiviral properties, emerges as an attractive candidate entering clinical trials to test its efficacy in early-stage treatment COVID-19 patients.

In-Line Mach–Zehnder Interferometers Based on a Capillary Hollow-Core Fiber Using Vernier Effect for a Highly Sensitive Temperature Sensor

In this paper, we propose a highly sensitive temperature sensor based on two cascaded Mach–Zehnder interferometers (MZIs) that work using the Vernier effect. The all-fiber MZIs were assembled by splicing a segment of capillary hollow-core fiber (CHCF) between two sections of multimode fibers (MMFs). This cascaded configuration exhibits a temperature sensitivity of 1.964 nm/°C in a range from 10 to 70 °C, which is ~67.03 times higher than the sensitivity of the single MZI. Moreover, this device exhibits a high-temperature resolution of 0.0153 °C. A numerical analysis was carried out to estimate the devices’ temperature sensitivity and calculate the magnification of the sensitivity produced by the Vernier effect. The numerical results have an excellent agreement with the experimental results and provide a better insight into the working principle of the MZI devices. The sensor’s performance, small size, and easy fabrication make us believe that it is an attractive candidate for temperature measurement in biological applications.

Electrospinning of chitosan-based nanofibers: from design to prospective applications

Chitosan is a biopolymer originating from renewable resources, with great properties which make it an attractive candidate for plenty of applications of contemporary interest. By manufacturing chitosan into nanofibers using the electrospinning method, its potential is amplified due to the enhancement of the active surface and the low preparation cost. Many attempts were made with the aim of preparing chitosan-based nanofibers with controlled morphology targeting their use for tissue engineering, wound healing, food packaging, drug delivery, air and water purification filters. This was a challenging task, which resulted in a high amount of data, sometimes with apparent contradictory results. In this light, the goal of the paper is to present the main routes reported in the literature for chitosan electrospinning, stressing the advantages and disadvantages of each of them. Special emphasis is placed on the influence of various electrospinning parameters on the morphological characteristics of the fibers and their suitability for distinct applications.