Radiation damage and derivatization in macromolecular crystallography: a structure factor's perspective
2016 ◽
Vol 72
(3)
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pp. 388-394
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Keyword(s):
X Ray
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During, or even after, data collection the presence and effects of radiation damage in macromolecular crystallography may not always be immediately obvious. Despite this, radiation damage is almost always present, with site-specific damage occurring on very short time (dose) scales well before global damage becomes apparent. A result of both site-specific radiation damage and derivatization is a change in the relative intensity of reflections. The size and approximate rate of onset of X-ray-induced transformations is compared with the changes expected from derivatization, and strategies for minimizing radiation damage are discussed.
2013 ◽
Vol 46
(4)
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pp. 1225-1230
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2020 ◽
Vol 76
(12)
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pp. 616-622
1999 ◽
Vol 55
(10)
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pp. 1641-1653
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2011 ◽
Vol 44
(2)
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pp. 433-436
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2009 ◽
Vol 170
(1-3)
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pp. 19-24
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