Enabling the Analysis of Mental Health Patterns Using an Efficient Machine Learning Approach

Author(s):  
Saleh Afzoon ◽  
Nabi Rezvani ◽  
Farshad Khunjush
2021 ◽  
Author(s):  
Zaid Abdi Alkareem Alyasseri ◽  
Mohammed Azmi Al-Betar ◽  
Mohammed A. Awadallah ◽  
Sharif Naser Makhadmeh ◽  
Osama Ahmad Alomari ◽  
...  

2021 ◽  
pp. 116073
Author(s):  
Paulo Augusto de Lima Medeiros ◽  
Gabriel Vinícius Souza da Silva ◽  
Felipe Ricardo dos Santos Fernandes ◽  
Ignacio Sánchez-Gendriz ◽  
Hertz Wilton Castro Lins ◽  
...  

2017 ◽  
Vol 14 (11) ◽  
pp. 141-150 ◽  
Author(s):  
Lingwen Zhang ◽  
Yishun Li ◽  
Yajun Gu ◽  
Wenkao Yang

2021 ◽  
Author(s):  
Xin Bai ◽  
Xin Guo ◽  
Linjun Wang

Diabatization of one-electron states in flexible molecular aggregates is a great challenge due to the presence of surface crossings between molecular orbital (MO) levels and the complex interaction between MOs of neighboring molecules. In this work, we present an efficient machine learning approach to calculate electronic couplings between quasi-diabatic MOs without the need of nonadiabatic coupling calculations. Using MOs of rigid molecules as references, the MOs that can be directly regarded to be quasi-diabatic in molecular dynamics are selected out, state tracked, and phase corrected. On the basis of this information, artificial neural networks are trained to characterize the structure-dependent onsite energies of quasi-diabatic MOs and the inter-molecular electronic couplings. A representative sequence of DNA is systematically studied as an illustration. Smooth time evolution of electronic couplings in all base pairs is obtained with quasi-diabatic MOs. Especially, our method can calculate electronic couplings between different quasi-diabatic MOs independently, and thus possesses unique advantages in many applications.


2021 ◽  
Author(s):  
Ravi Iyer ◽  
Elizabeth Seabrook ◽  
Suku Sukunesan ◽  
Maja Nedeljkovic ◽  
Denny Meyer

Abstract We aimed to demonstrate how a large collection of publicly accessible Australian Coroner’s Court case files (n=4459) (2009-2019) can be automatically classified for determination of death by suicide, presence of mental health disorder and sex of deceased via Natural Language Processing (NLP) methods - supervised machine learning and unsupervised dictionary-based and string search based approaches. We achieved superior levels of accuracy in the machine learning classification (Gradient Boosting vs. Random Forest baseline) of deaths by suicide of 83.3% (sensitivity = 85.1%, Specificity = 79.1%) and an accuracy of 98.3% for the dictionary-based classification of mental health disorder, as defined by the OCD-10 (sensitivity = 99.0%, specificity = 97.9%). Our machine learning approach automatically classified 24.2% (1078/4459) of the case files as referring to deaths by suicide while 63.7% (2940/4459) where classified as exhibiting a mental health disorder1. We employed a two-stage machine learning approach involving feature engineering, followed by predictive modelling in the second. Feature engineering involved several steps including removal of low value text, parts of speech analysis, term document weighting and topic clustering. Predictive classification involved extensive hyperparameter tuning to yield the most accurate model. We validated our models against a manually pre-coded subsample of case files, and also via binary logistic regression to test the contribution of each classified mental health disorder against determinations of deaths by suicide according to extant literature. This validation step confirmed elevated odds of suicide attributed to diagnoses of Depression, Schizophrenia and Obsessive Compulsive Disorder. Finally, we offer a short case study to demonstrate the efficacy of our approach in investigating a subset of case findings referring to suicides resulting from family violence. We offer a proof of concept model that demonstrates an objective and scalable approach to the analysis of legal texts. The use of NLP methods in analysing Coroner's Court case findings has important implications for the ongoing development of a real-time surveillance of suicide system in Australia.


2022 ◽  
Vol 12 ◽  
Author(s):  
Liana C. L. Portugal ◽  
Camila Monteiro Fabricio Gama ◽  
Raquel Menezes Gonçalves ◽  
Mauro Vitor Mendlowicz ◽  
Fátima Smith Erthal ◽  
...  

Background: Healthcare workers are at high risk for developing mental health problems during the COVID-19 pandemic. There is an urgent need to identify vulnerability and protective factors related to the severity of psychiatric symptoms among healthcare workers to implement targeted prevention and intervention programs to reduce the mental health burden worldwide during COVID-19.Objective: The present study aimed to apply a machine learning approach to predict depression and PTSD symptoms based on psychometric questions that assessed: (1) the level of stress due to being isolated from one's family; (2) professional recognition before and during the pandemic; and (3) altruistic acceptance of risk during the COVID-19 pandemic among healthcare workers.Methods: A total of 437 healthcare workers who experienced some level of isolation at the time of the pandemic participated in the study. Data were collected using a web survey conducted between June 12, 2020, and September 19, 2020. We trained two regression models to predict PTSD and depression symptoms. Pattern regression analyses consisted of a linear epsilon-insensitive support vector machine (ε-SVM). Predicted and actual clinical scores were compared using Pearson's correlation coefficient (r), the coefficient of determination (r2), and the normalized mean squared error (NMSE) to evaluate the model performance. A permutation test was applied to estimate significance levels.Results: Results were significant using two different cross-validation strategies to significantly decode both PTSD and depression symptoms. For all of the models, the stress due to social isolation and professional recognition were the variables with the greatest contributions to the predictive function. Interestingly, professional recognition had a negative predictive value, indicating an inverse relationship with PTSD and depression symptoms.Conclusions: Our findings emphasize the protective role of professional recognition and the vulnerability role of the level of stress due to social isolation in the severity of posttraumatic stress and depression symptoms. The insights gleaned from the current study will advance efforts in terms of intervention programs and public health messaging.


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