scholarly journals A new method for characterization of coronary plaque composition via IVUS images

2009 ◽  
Author(s):  
Arash Taki ◽  
Alireza Roodaki ◽  
Olivier Pauly ◽  
S. K. Setarehdan ◽  
Gozde Unal ◽  
...  
Keyword(s):  
Coronary Plaque ◽  
New Method ◽  
Plaque Composition

scholarly journals Coronary CT Angiography in the Quantitative Assessment of Coronary Plaques

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Zhonghua Sun ◽  
Lei Xu
Keyword(s):  
Quantitative Assessment ◽  
Coronary Plaque ◽  
Plaque Composition ◽  
Coronary Syndrome ◽  
Coronary Ct ◽  
Vulnerable Plaques ◽  
Clinical Presentations ◽  
Recent Developments ◽  
The Relationship

Coronary computed tomography angiography (CCTA) has been recently evaluated for its ability to assess coronary plaque characteristics, including plaque composition. Identification of the relationship between plaque composition by CCTA and patient clinical presentations may provide insight into the pathophysiology of coronary artery plaque, thus assisting identification of vulnerable plaques which are associated with the development of acute coronary syndrome. CCTA-generated 3D visualizations allow evaluation of both coronary lesions and lumen changes, which are considered to enhance the diagnostic performance of CCTA. The purpose of this review is to discuss the recent developments that have occurred in the field of CCTA with regard to its diagnostic accuracy in the quantitative assessment of coronary plaques, with a focus on the characterization of plaque components and identification of vulnerable plaques.

A new method for approximation of closed convex subsets of B(H)

Filomat ◽  
2017 ◽  
Vol 31 (19) ◽  
pp. 6005-6013
Author(s):  
Mahdi Iranmanesh ◽  
Fatemeh Soleimany
Keyword(s):  
Best Approximation ◽  
Numerical Range ◽  
New Method ◽  
C Algebra ◽  
Convex Subsets

In this paper we use the concept of numerical range to characterize best approximation points in closed convex subsets of B(H): Finally by using this method we give also a useful characterization of best approximation in closed convex subsets of a C*-algebra A.

On a generalization of the Rényi–Srivastava characterization of the Poisson law

2021 ◽  
Vol 58 (1) ◽  
pp. 68-82
Author(s):  
Jean-Renaud Pycke
Keyword(s):  
Life Insurance ◽  
Collective Model ◽  
New Method ◽  
Bell Polynomials ◽  
Explicit Formulas ◽  
Compound Distributions ◽  
Poisson Law ◽  
Pierre Loti

AbstractWe give a new method of proof for a result of D. Pierre-Loti-Viaud and P. Boulongne which can be seen as a generalization of a characterization of Poisson law due to Rényi and Srivastava. We also provide explicit formulas, in terms of Bell polynomials, for the moments of the compound distributions occurring in the extended collective model in non-life insurance.

scholarly journals Spectroscopic characterization of a thermodynamically stable doubly charged diatomic molecule: MgAr2+

2021 ◽  
Author(s):  
Dominik Wehrli ◽  
Matthieu Génévriez ◽  
Frédéric Merkt
Keyword(s):  
High Resolution ◽  
Diatomic Molecule ◽  
Spectroscopic Characterization ◽  
New Method ◽  
High Resolution Spectroscopy ◽  
Singly Charged ◽  
Doubly Charged

We present a new method to study doubly charged molecules relying on high-resolution spectroscopy of the singly charged parent cation, and report on the first spectroscopic characterization of a thermodynamically stable diatomic dication, MgAr2+.

scholarly journals A New Ultrasensitive Bioluminescence-Based Method for Assaying Monoacylglycerol Lipase

2021 ◽  
Vol 22 (11) ◽  
pp. 6148
Author(s):  
Matteo Miceli ◽  
Silvana Casati ◽  
Pietro Allevi ◽  
Silvia Berra ◽  
Roberta Ottria ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Kinetic Constants ◽  
New Method ◽  
Monoacylglycerol Lipase ◽  
Enzymatic Cleavage ◽  
Highly Sensitive ◽  
Bioluminescence Assay ◽  
Identification And Characterization ◽  
In Cells

A novel bioluminescent Monoacylglycerol lipase (MAGL) substrate 6-O-arachidonoylluciferin, a D-luciferin derivative, was synthesized, physico-chemically characterized, and used as highly sensitive substrate for MAGL in an assay developed for this purpose. We present here a new method based on the enzymatic cleavage of arachidonic acid with luciferin release using human Monoacylglycerol lipase (hMAGL) followed by its reaction with a chimeric luciferase, PLG2, to produce bioluminescence. Enzymatic cleavage of the new substrate by MAGL was demonstrated, and kinetic constants Km and Vmax were determined. 6-O-arachidonoylluciferin has proved to be a highly sensitive substrate for MAGL. The bioluminescence assay (LOD 90 pM, LOQ 300 pM) is much more sensitive and should suffer fewer biological interferences in cells lysate applications than typical fluorometric methods. The assay was validated for the identification and characterization of MAGL modulators using the well-known MAGL inhibitor JZL184. The use of PLG2 displaying distinct bioluminescence color and kinetics may offer a highly desirable opportunity to extend the range of applications to cell-based assays.

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