CNN-type myocardial infarction prediction based on cardiac cycle determination

2021 ◽  
Author(s):  
Tsubasa Kanai ◽  
Nari Tanabe ◽  
Yasuo Miyagi ◽  
Junya Aoyama
Keyword(s):  
Myocardial Infarction ◽  
Cardiac Cycle

scholarly journals Improvements in Regional Left Ventricular Function Following Late Percutaneous Coronary Intervention for Anterior Myocardial Infarction

2017 ◽  
Vol 11 ◽  
pp. 117954681774663
Author(s):  
Srilakshmi M Adhyapak ◽  
Prahlad G Menon ◽  
Kiron Varghese ◽  
Abhinav Mehra ◽  
SB Lohitashwa ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Cardiac Cycle ◽  
Coronary Intervention ◽  
Anterior Wall ◽  
Left Ventricular ◽  
Anterior Myocardial Infarction ◽  
Regional Left Ventricular Function ◽  
Percutaneous Coronary ◽  
Anterior Wall Myocardial Infarction

Background: Late revascularization following a myocardial infarction has questionable clinical benefit. Methods: We studied 13 patients with anterior wall myocardial infarction who underwent percutaneous coronary intervention within 2 weeks of the primary event, by quantitative analysis of 2-dimensional echocardiographic images. Endocardial segmentations of the left ventricular (LV) endocardium from the 4-chamber views were studied over time to establish cumulative wall displacements (CWDs) throughout the cardiac cycle. Results: Left ventricular end-systolic volume decreased to 42 ± 8 mL/body surface area ( P = .034) and LV ejection fraction improved to 52% ± 7% ( P = .04). Analysis of LV endocardial CWD demonstrated significant improvements in mid-systolic to late-systolic phases in the apical LV segments, from 3.5 ± 0.32 to 5.89 ± 0.43 mm ( P = .019). Improvements in CWD were also observed in the late-diastolic phase of the cardiac cycle, from 1.50 ± 0.42 to 1.76 ± 0.52 mm ( P = .04). Conclusions: In our pilot patient cohort, following late establishment of infarct-related artery patency following an anterior wall myocardial infarction, regional improvements were noted in the LV apical segments during systole and late diastole.

3080Postsystolic shortening yields novel and independent prognostic information on cardiovascular events and mortality in patients with type 2 diabetes

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
P Brainin ◽  
M T Jensen ◽  
T Biering-Soerensen ◽  
R Moegelvang ◽  
T Fritz-Hansen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Primary Endpoint ◽  
Cardiovascular Events ◽  
Cardiac Cycle ◽  
Secondary Endpoint ◽  
Maximum Strain ◽  
Prognostic Information

Abstract Background Cardiovascular disease is the leading cause of death and disability in patients with type 2 diabetes. We aimed to evaluate if postsystolic shortening, a marker of impaired myocardial function, may provide prognostic information on cardiovascular events and mortality in patients with type 2 diabetes. Method We prospectively studied 783 patients with diabetes type 2 (63% male, age 65 [58, 70] years; HbA1c 54 [48, 65] mmol/mol; diabetes duration 11 [6, 17] years) who underwent speckle tracking echocardiography. Patients with left bundle branch block, atrial fibrillation and a history of heart failure and myocardial infarction were excluded. The primary endpoint was the composite of incident heart failure, myocardial infarction and cardiovascular death. The secondary endpoint was all-cause death. We defined the postsystolic index (PSI) as: [100x (maximum strain in cardiac cycle – peak systolic strain)/ (maximum strain in cardiac cycle)]. Results During the median follow-up of 4.9 years [4.2, 5.3], 87 patients (11%) reached the primary endpoint and 80 (10%) died from any cause. Each 1% increase in the PSI was associated with the primary (HR 1.07 95% CI 1.02–1.13, P<0.001, Fig A) and secondary endpoint (HR 1.09 95% CI 1.04–1.14, P<0.001, Fig B). After adjusting for age, sex, hypertension, smoking, duration of diabetes, cholesterol, eGFR, left ventricular ejection fraction and mass index, E/A-ratio, deceleration time and left atrial volume index, the PSI remained an independent predictor of both endpoints; primary (HR 1.07 per 1% increase 95% CI 1.01–1.14, P=0.028) and secondary endpoint (HR 1.07 per 1% increase, 95% CI 1.01–1.14, P=0.022). PSI and the endpoints Conclusion In patients with type 2 diabetes, assessment of PSI yields novel and independent prognostic information on cardiovascular events and mortality. Hence, PSI may offer guidance on risk stratification in patients with type 2 diabetes.

scholarly journals Contrast Echocardiography with a Quantitative Assessment of Myocardial Perfusion in Patients with Previous Q-Wave Myocardial Infarction

Kardiologiia ◽  
2020 ◽  
Vol 60 (2) ◽  
pp. 17-23
Author(s):  
I. N. Umnov ◽  
A. L. Bobrov ◽  
M. N. Alekhin
Keyword(s):  
Myocardial Infarction ◽  
Myocardial Perfusion ◽  
Cardiac Cycle ◽  
High Efficiency ◽  
Contrast Echocardiography ◽  
Ultrasound Contrast Agent ◽  
Left Ventricular ◽  
Myocardial Segment ◽  
Ultrasound Signal ◽  
Q Wave

Objective. To assess possibilities of contrast echocardiography with quantitative evaluation of myocardial perfusion in patients with previous Q-wave myocardial infarction.Materials and Methods. We examined 15 men (42-72 years) with coronary artery disease and previous myocardial infarction, and pathological Q-wave in 2 or more ECG leads. Quantification of left ventricular (LV) myocardial perfusion was performed by calculating of the ultrasound signal tissue intensity from the LV myocardial segments during intravenous administration of the ultrasound contrast agent (SonoVue). The Tissue intensive curve (TIC) analysis was done in the end-diastolic period before and on the fourth cardiac cycle after applying the "flash". Changes in the intensity of myocardial perfusion (A4, dB) was estimated as the difference between the intensity values of the ultrasound signal in the myocardial segment during the period of filling the contrast bubbles on 4-th cardiac cycle and before applying the «flash». Measurements were performed in 16 segments of the LV. A contrast cardiac magnetic resonance imaging (contrast MRI) was performed in order to verify the LV scar. Fibrotic changes of 50% of myocardial wall or more were considered as signs of post-infarction scar.Results. The dynamics of perfusion and scar presence in 240 myocardial segments were evaluated. The median A4 was 1 dB (range, -20 to 10 dB). MRI revealed 82 of 240 segments with the large-focal scar. The effectiveness of the diagnostic test (quantitative contrast perfusion echocardiography with A4 assessment) to detect myocardial scar was investigated. ROC curve analysis showed good model quality, AUC=0,787 (0,730-0,837); sensitivity 82.9%; specificity 75.3%; p<0.01. The cut-off point for A4 was -1.Conclusion. A new approach to quantitative contrast assessment of perfusion allows to identify perfusion disorders with high efficiency in patients with previous Q-wave myocardial infarction.

scholarly journals Upstroke Time Per Cardiac Cycle as A Novel Parameter for Mortality Prediction in Patients with Acute Myocardial Infarction

2020 ◽  
Vol 9 (4) ◽  
pp. 904 ◽  
Author(s):  
Po-Chao Hsu ◽  
Wen-Hsien Lee ◽  
Wei-Chung Tsai ◽  
Ying-Chih Chen ◽  
Nai-Yu Chi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Predictive Value ◽  
Cardiac Cycle ◽  
Multivariable Analysis ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Basic Model ◽  
Overall Mortality

Background: Acute myocardial infarction (AMI) is one of the leading causes of death in the world. How to simply predict mortality for AMI patients is important because the appropriate treatment should be done for the patients with higher risk. Recently, a novel parameter of upstroke time per cardiac cycle (UTCC) in lower extremities was reported to be a good predictor of peripheral artery disease and mortality in elderly. However, there was no literature discussing the usefulness of UTCC for prediction of cardiovascular (CV) and overall mortality in AMI patients. Methods: 184 AMI patients admitted to the cardiac care unit were enrolled. Ankle-brachial index (ABI) and UTCC were measured by an ABI-form device in the same day of admission. Results: The median follow-up to mortality was 71 months. There were 36 CV and 124 overall mortality. Higher UTCC was associated with increased CV and overall mortality after multivariable analysis (P = 0.033 and P < 0.001, respectively). However, ABI was only associated with CV mortality and overall mortality in the univariable analysis but became insignificant after the multivariable analysis. In addition, after adding UTCC into a basic model including important clinical parameters, left ventricular ejection fraction, Charlson comorbidity index, and ABI, we found the basic model + UTCC had a better predictive value for overall mortality than the basic model itself (P < 0.001). Conclusions: Our study is the first one to evaluate the usefulness of UTCC in AMI patients for prediction of long-term mortality. Our study showed UTCC was an independent predictor of long-term CV and overall mortality and had an additive predictive value for overall mortality beyond conventional parameters. Therefore, screening AMI patients by UTCC might help physicians to identify the high-risk group with increased mortality.

Heart and blood supply

2018 ◽  
Author(s):  
Hugh Devlin ◽  
Rebecca Craven
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Cardiovascular Disease ◽  
Infective Endocarditis ◽  
Blood Loss ◽  
Cerebrovascular Accident ◽  
Cardiac Cycle ◽  
Oral Bacteria ◽  
Transient Ischaemic Attacks ◽  
Heart Physiology

The heart in relation to dentistry is the topic of this chapter. Heart physiology is described with respect to the cardiac cycle, control of contraction, ECG, and arrhythmias. Control of the cardiovascular system is next considered and the clinical application of this in fainting, shock, and blood loss. Atherosclerosis, angina, and myocardial infarction are described. This leads to a discussion of heart failure and drugs commonly used in cardiovascular disease. Infective endocarditis and rheumatic fever are discussed and the associations between oral bacteria and cardiovascular disease. The concluding section deals with stroke (cerebrovascular accident or CVA), transient ischaemic attacks (TIA) and vascular dementia.

Temporal and Spatial Heterogeneity of Blood Supply to the Heart: Visualization and Interpretation

1997 ◽  
Vol 36 (04/05) ◽  
pp. 319-321 ◽  
Author(s):  
F. Kajiya
Keyword(s):  
Myocardial Infarction ◽  
Spatial Heterogeneity ◽  
Cardiac Cycle ◽  
Coronary Circulation ◽  
Blood Velocity ◽  
Flow Heterogeneity ◽  
Velocity Waveform ◽  
Flow Fluctuation ◽  
Temporal And Spatial ◽  
Temporal And Spatial Heterogeneity

Abstract:Blood flow of the heart muscle (the coronary circulation) exhibits both temporal and spatial heterogeneity. In this paper, the unique blood velocity waveform during a cardiac cycle, the flow fluctuation of a longer period and the within-layer spatial flow heterogeneity of the coronary circulation are described with a reference to the pathogenesis of angina pectoris and myocardial infarction.

An electron microscopic study of the intra-myocardial lesions in cases of acute myocardial infarction

1978 ◽  
Vol 36 (2) ◽  
pp. 484-485
Author(s):  
Masahiro Ono ◽  
Kaoru Aihara ◽  
Gompachi Yajima
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Vessels ◽  
Vascular Wall ◽  
Vascular Changes ◽  
Electron Microscopic ◽  
Main Trunk ◽  
Mechanical Destruction ◽  
Transmission Electron ◽  
Myocardial Lesions

The pathogenesis of the arteriosclerosis in the acute myocardial infarction is the matter of the extensive survey with the transmission electron microscopy in experimental and clinical materials. In the previous communication,the authors have clarified that the two types of the coronary vascular changes could exist. The first category is the case in which we had failed to observe no occlusive changes of the coronary vessels which eventually form the myocardial infarction. The next category is the case in which occlusive -thrombotic changes are observed in which the myocardial infarction will be taken placed as the final event. The authors incline to designate the former category as the non-occlusive-non thrombotic lesions. The most important findings in both cases are the “mechanical destruction of the vascular wall and imbibition of the serous component” which are most frequently observed at the proximal portion of the coronary main trunk.

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