Wireless Web services are becoming a reality, if they have not already. The unique characteristics of the mobile devices and wireless communication medium, such as limited computing power, limited network bandwidth, limited battery life, unpredictable online time, mobility, and so forth,, imply that the infrastructure for wireless Web services will be very different from its wired counterpart. This chapter discusses the challenges and the stateof- the-art solutions to ensure highly performable wireless Web services. In particular, this chapter’s focus is on three technical issues: optimization of the wireless Web services messaging protocol, caching, and fault tolerance. Finally, limitations of the current approaches and an outline of future research directions on wireless Web services are also discussed.