Classification of bacterial morphotypes from images of ZN-stained sputum-smears towards diagnosing drug-resistant TB

Author(s):  
Rijul Saurabh Soans ◽  
A G Ramakrishnan ◽  
V P Shenoy ◽  
Ramesh R Galigekere
The Lancet ◽  
2000 ◽  
Vol 356 (9245) ◽  
pp. 1932
Author(s):  
Annelies van Rie ◽  
Nulda Beyers ◽  
Don Enarson ◽  
Rob Warren ◽  
Paul van Helden

2020 ◽  
Vol 15 ◽  
Author(s):  
Ewelina Pyzik ◽  
Renata Urban-Chmiel ◽  
Radosław P. Radzki

Aim: The aim of review was to comprehensively characterize the antimicrobial efficacy of bacteriophages in eliminating pathogens occurring in companion animals, as an alternative to antibiotics for controlling infections that pose potential threats to the health and life of people and to the environment. Methods: The review contains detailed information on the characteristics and classification of bacteriophages and an analysis of their life cycle. The dominant element is a detailed analysis of the experimental use of bacteriophages in combating infections caused by various microorganisms in companion animals with regard to their potential use in therapy. Results: It seems that in the near future phage therapies will provide an alternative to antibiotics in the treatment of diseases caused by multi-drug resistant bacteria in people and animals. Conclusions: The effectiveness of phages therapies depends on many factors and the properties of the bacteriophages themselves, which requires comprehensive knowledge of them.


The Lancet ◽  
2000 ◽  
Vol 356 (9223) ◽  
pp. 22-25 ◽  
Author(s):  
Annelies Van Rie ◽  
Robin Warren ◽  
Madalene Richardson ◽  
Robert P Gie ◽  
Donald A Enarson ◽  
...  

Viruses ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 538
Author(s):  
Zainab Usman ◽  
Stoyan Velkov ◽  
Ulrike Protzer ◽  
Michael Roggendorf ◽  
Dmitrij Frishman ◽  
...  

Hepatitis D virus (HDV) causes the most severe form of viral hepatitis, which may rapidly progress to liver cirrhosis and hepatocellular carcinoma (HCC). It has been estimated that 15–20 million people worldwide are suffering from the chronic HDV infection. Currently, no effective therapies are available to treat acute or chronic HDV infection. The remarkable sequence variability of the HDV genome, particularly within the hypervariable region has resulted in the provisional classification of eight major genotypes and various subtypes. We have developed a specialized database, HDVdb, which contains a collection of partial and complete HDV genomic sequences obtained from the GenBank and from our own patient cohort. HDVdb enables the researchers to investigate the genetic variability of all available HDV sequences, correlation of genotypes to epidemiology and pathogenesis. Additionally, it will contribute in understanding the drug resistant mutations and develop effective vaccines against HDV infection. The database can be accessed through a web interface that allows for static and dynamic queries and offers integrated generic and specialized sequence analysis tools, such as annotation, genotyping, primer prediction, and phylogenetic analyses.


The Lancet ◽  
2000 ◽  
Vol 356 (9245) ◽  
pp. 1931-1932
Author(s):  
Kathy DeRiemer ◽  
Ma de Lourdes García García ◽  
Alfredo Ponce de León Garduño ◽  
José Sifuentes Osornio ◽  
Peter M Small

The Lancet ◽  
2000 ◽  
Vol 356 (9245) ◽  
pp. 1930-1931
Author(s):  
Pamela Sonnenberg ◽  
Peter Godfrey-Faussett ◽  
Judith R Glynn ◽  
Stuart Shearer ◽  
Jill Murray

1966 ◽  
Vol 24 ◽  
pp. 21-23
Author(s):  
Y. Fujita

We have investigated the spectrograms (dispersion: 8Å/mm) in the photographic infrared region fromλ7500 toλ9000 of some carbon stars obtained by the coudé spectrograph of the 74-inch reflector attached to the Okayama Astrophysical Observatory. The names of the stars investigated are listed in Table 1.


Author(s):  
Gerald Fine ◽  
Azorides R. Morales

For years the separation of carcinoma and sarcoma and the subclassification of sarcomas has been based on the appearance of the tumor cells and their microscopic growth pattern and information derived from certain histochemical and special stains. Although this method of study has produced good agreement among pathologists in the separation of carcinoma from sarcoma, it has given less uniform results in the subclassification of sarcomas. There remain examples of neoplasms of different histogenesis, the classification of which is questionable because of similar cytologic and growth patterns at the light microscopic level; i.e. amelanotic melanoma versus carcinoma and occasionally sarcoma, sarcomas with an epithelial pattern of growth simulating carcinoma, histologically similar mesenchymal tumors of different histogenesis (histiocytoma versus rhabdomyosarcoma, lytic osteogenic sarcoma versus rhabdomyosarcoma), and myxomatous mesenchymal tumors of diverse histogenesis (myxoid rhabdo and liposarcomas, cardiac myxoma, myxoid neurofibroma, etc.)


Author(s):  
Irving Dardick

With the extensive industrial use of asbestos in this century and the long latent period (20-50 years) between exposure and tumor presentation, the incidence of malignant mesothelioma is now increasing. Thus, surgical pathologists are more frequently faced with the dilemma of differentiating mesothelioma from metastatic adenocarcinoma and spindle-cell sarcoma involving serosal surfaces. Electron microscopy is amodality useful in clarifying this problem.In utilizing ultrastructural features in the diagnosis of mesothelioma, it is essential to appreciate that the classification of this tumor reflects a variety of morphologic forms of differing biologic behavior (Table 1). Furthermore, with the variable histology and degree of differentiation in mesotheliomas it might be expected that the ultrastructure of such tumors also reflects a range of cytological features. Such is the case.


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