High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System

2018 ◽  
Vol 28 (6) ◽  
pp. 1-7 ◽  
Author(s):  
Da Li ◽  
Yong Ren
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gradient Magnetic Field ◽  
High Gradient

scholarly journals The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip

2019 ◽  
Vol 9 (3) ◽  
pp. 360-373 ◽  
Author(s):  
Ali Alirezaie Alavijeh ◽  
Mohammad Barati ◽  
Meisam Barati ◽  
Hussein Abbasi Dehkordi
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Cell Growth ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cell Types ◽  
Diagnosis And Treatment ◽  
Abnormal Cell ◽  
On Chip

Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell types precisely. This study describes usual strategies and consideration for the synthesis of MNPs and incorporates payload drug on MNPs. They have advantages such as visual targeting and delivering which will be discussed in this review. In addition, we considered body magnetic field to make drug delivery process more effective and safer by the application of MNPs and tumor-on-chip.

Design and Electromagnetic FEM Analysis of a High Gradient Magnet for the Magnetic Targeted Drug Delivery System

2013 ◽  
Vol 753-755 ◽  
pp. 995-1001
Author(s):  
Rui Lin Zhang ◽  
Jie Feng ◽  
Ya Nan Qu ◽  
Ping Geng ◽  
Shou Liang Qi
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Open Circuit ◽  
Experimental Result ◽  
High Gradient ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

Magnetic targeted-drug delivery system (MTDs) works as a promising cancer treatment approach, and is entering the mainstream. It applies an external magnetic field to attract and guide the magnetic nanoparticles (MNPs) carrying treatment agent and targeted antibodies to the lesion region. Its key factor is the high gradient magnet. Here three types of magnets are proposed, i.e., open circuit magnet, close circuit magnet with planar poles, and close circuit magnet with concave-convex poles. And then their magnet field distributions are calculated through the finite element method (FEM). The simulation results are compared with each other and the measurement of Gauss Meter for the manufactured magnet, and the primary experimental result is also reported. It is found the closed magnet circuit with concave-convex poles shows about 2.0 and 1.2 times higher magnetic field intensity (H) than the open magnet circuit and the close magnet circuit with planar poles, respectively. Most important is it owns largest Grad (H) (1.0 e6 A/m2) among three magnets. The simulation agrees well with the measurement, and the primary experimental results also show the magnet can attract MNPs efficiently. Hence the calculation enables provide with credible input for the further trajectory simulation for MNPs.

scholarly journals Doxorobicin as cargo in a redox-responsive drug delivery system capped with water dispersible ZnS nanoparticles

RSC Advances ◽  
2020 ◽  
Vol 10 (27) ◽  
pp. 15825-15835
Author(s):  
Lukáš Žid ◽  
Vladimír Zeleňák ◽  
Vladimír Girman ◽  
Jozef Bednarčík ◽  
Adriana Zeleňáková ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Capping Agent ◽  
Zns Nanoparticles ◽  
Water Dispersible ◽  
Redox Responsive ◽  
Premature Release

Redox-responsive drug delivery system was studied. ZnS nanoparticles served as pore capping agent to prevent premature release of anticancer drug. Such cargo can be monitored by magnetic field which opens possibilities its use in theranostics.

Magnetic stimulus responsive vancomycin drug delivery system based on chitosan microbeads embedded with magnetic nanoparticles

2017 ◽  
Vol 106 (6) ◽  
pp. 2169-2176 ◽  
Author(s):  
Ankita Mohapatra ◽  
Michael A. Harris ◽  
David LeVine ◽  
Madhav Ghimire ◽  
Jessica A. Jennings ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Magnetic Stimulus ◽  
Stimulus Responsive
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