Can low serum brain‐derived neurotrophic factor levels be associated with lifelong premature ejaculation?; A pilot study

Andrologia ◽  
2020 ◽  
Vol 52 (10) ◽  
Author(s):  
Yavuz T. Atik ◽  
Ahmet Gokce ◽  
Fikret Halis ◽  
Haci Ibrahim Cimen
Keyword(s):  
Pilot Study ◽  
Neurotrophic Factor ◽  
Premature Ejaculation ◽  
Brain Derived Neurotrophic Factor ◽  
Lifelong Premature Ejaculation ◽  
Low Serum

scholarly journals Low serum brain-derived neurotrophic factor is associated with suicidal ideation in major depressive disorder

2019 ◽  
Vol 273 ◽  
pp. 108-113 ◽  
Author(s):  
Maryam S. Khan ◽  
Gwyneth W.Y. Wu ◽  
Victor I. Reus ◽  
Christina M. Hough ◽  
Daniel Lindqvist ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicidal Ideation ◽  
Depressive Disorder ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Major Depressive ◽  
Low Serum

Low serum levels of brain-derived neurotrophic factor and epidermal growth factor in patients with chronic schizophrenia

2008 ◽  
Vol 101 (1-3) ◽  
pp. 58-66 ◽  
Author(s):  
Yumiko Ikeda ◽  
Noriaki Yahata ◽  
Itsuo Ito ◽  
Masatoshi Nagano ◽  
Tomoko Toyota ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Neurotrophic Factor ◽  
Chronic Schizophrenia ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Epidermal Growth ◽  
Low Serum

scholarly journals Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0240342
Author(s):  
Robin M. Voigt ◽  
Shohreh Raeisi ◽  
Jingyun Yang ◽  
Sue Leurgans ◽  
Christopher B. Forsyth ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Pilot Study ◽  
Neurotrophic Factor ◽  
Intestinal Barrier ◽  
Brain Derived Neurotrophic Factor ◽  
Barrier Dysfunction ◽  
Barrier Integrity ◽  
Risk Of Death ◽  
Intestinal Barrier Integrity ◽  
Global Cognition

The inflammatory hypothesis posits that sustained neuroinflammation is sufficient to induce neurodegeneration and the development of Alzheimer’s disease (AD) and Alzheimer’s dementia. One potential source of inflammation is the intestine which harbors pro-inflammatory microorganisms capable of promoting neuroinflammation. Systemic inflammation is robustly associated with neuroinflammation as well as low levels of brain derived neurotrophic factor (BDNF) in the systemic circulation and brain. Thus, in this pilot study, we tested the hypothesis that intestinal barrier dysfunction precedes risk of death, incident AD dementia and MCI, cognitive impairment and neuropathology. Serum BDNF was associated with changes in global cognition, working memory, and perceptual speed but not risk of death, incident AD dementia, incident MCI, or neuropathology. Neither of the markers of intestinal barrier integrity examined, including lipopolysaccharide binding protein (LBP) nor intestinal fatty acid binding protein (IFABP), were associated with risk of death, incident AD dementia, incident mild cognitive impairment (MCI), change in cognition (global or domains), or neuropathology. Taken together, the data in this pilot study suggest that intestinal barrier dysfunction does not precede diagnosis of AD or MCI, changes in cognition, or brain pathology. However, since MCI and AD are related to global cognition, the findings with BDNF and the contiguous cognitive measures suggest low power with the trichotomous cognitive status measures. Future studies with larger sample sizes are necessary to further investigate the results from this pilot study.

Extreme conditioning session augments brain-derived neurotrophic factor in healthy novice participants: a pilot study

2021 ◽  
Author(s):  
Emy Suelen Pereira ◽  
Walter Krause Neto ◽  
Atilio Sersun Calefi ◽  
Mariana Georgetti ◽  
Larissa Guerreiro ◽  
...  
Keyword(s):  
Pilot Study ◽  
Neurotrophic Factor ◽  
Conditioning Session ◽  
Brain Derived Neurotrophic Factor
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