Proton pump inhibitor use and hearing loss in patients with type 2 diabetes: evidence from a hospital‐based case‐control study and a population‐based cohort study

2021 ◽  
Author(s):  
Jeong Yee ◽  
Hye Won Han ◽  
Hye Sun Gwak
Keyword(s):  
Type 2 Diabetes ◽  
Hearing Loss ◽  
Cohort Study ◽  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Association between cardiometabolic disease and severe COVID-19: a nationwide case–control study of patients requiring invasive mechanical ventilation

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e044486 ◽  
Author(s):  
Per Svensson ◽  
Robin Hofmann ◽  
Henrike Häbel ◽  
Tomas Jernberg ◽  
Per Nordberg
Keyword(s):  
Type 2 Diabetes ◽  
Mechanical Ventilation ◽  
Case Control Study ◽  
Invasive Mechanical Ventilation ◽  
Population Based ◽  
Case Control ◽  
Population Type ◽  
Susceptible Patient ◽  
Control Study

AimsThe risks associated with diabetes, obesity and hypertension for severe COVID-19 may be confounded and differ by sociodemographic background. We assessed the risks associated with cardiometabolic factors for severe COVID-19 when accounting for socioeconomic factors and in subgroups by age, sex and region of birth.Methods and resultsIn this nationwide case–control study, 1.086 patients admitted to intensive care with COVID-19 requiring mechanical ventilation (cases), and 10.860 population-based controls matched for age, sex and district of residency were included from mandatory national registries. ORs with 95% CIs for associations between severe COVID-19 and exposures with adjustment for confounders were estimated using logistic regression. The median age was 62 years (IQR 52–70), and 3003 (24.9%) were women. Type 2 diabetes (OR, 2.3 (95% CI 1.9 to 2.7)), hypertension (OR, 1.7 (95% CI 1.5 to 2.0)), obesity (OR, 3.1 (95% CI 2.4 to 4.0)) and chronic kidney disease (OR, 2.5 (95% CI 1.7 to 3.7)) were all associated with severe COVID-19. In the younger subgroup (below 57 years), ORs were significantly higher for all cardiometabolic risk factors. The risk associated with type 2 diabetes was higher in women (p=0.001) and in patients with a region of birth outside European Union(EU) (p=0.004).ConclusionDiabetes, obesity and hypertension were all independently associated with severe COVID-19 with stronger associations in the younger population. Type 2 diabetes implied a greater risk among women and in non-EU immigrants. These findings, originating from high-quality Swedish registries, may be important to direct preventive measures such as vaccination to susceptible patient groups.Trial registration numberClinicaltrial.gov (NCT04426084).

scholarly journals Hearing Loss and Associated Factors in Iranian Patients with Type 2 Diabetes: A Case-Control Study

Thrita ◽  
2016 ◽  
Vol 5 (4) ◽  
Author(s):  
Saeed Nouri ◽  
Raika Jamali ◽  
Kurosh Gharagozli ◽  
Mohammad Reza Sharif ◽  
Bardia Jamali
Keyword(s):  
Type 2 Diabetes ◽  
Hearing Loss ◽  
Associated Factors ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Iranian Patients

Proton Pump Inhibitor Use and Risk of Colorectal Cancer: A Population-Based, Case–Control Study

2007 ◽  
Vol 133 (3) ◽  
pp. 755-760 ◽  
Author(s):  
Douglas J. Robertson ◽  
Heidi Larsson ◽  
Søren Friis ◽  
Lars Pedersen ◽  
John A. Baron ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

Perinatal Risk Factors in Young Adult-Onset Type 1 and Type 2 Diabetes—A Population-Based Case-Control Study

2009 ◽  
Vol 64 (8) ◽  
pp. 511-512
Author(s):  
Niina Lammi ◽  
Paul A. Blomstedt ◽  
Elena Moltchanova ◽  
Johan G. Eriksson ◽  
Jaakko Tuomilehto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Adult Onset ◽  
Perinatal Risk Factors ◽  
Control Study

scholarly journals Long-term excess risk of stroke in people with Type 2 diabetes in Sweden according to blood pressure level: a population-based case-control study

2017 ◽  
Vol 34 (4) ◽  
pp. 522-530 ◽  
Author(s):  
C. Hedén Ståhl ◽  
M. Lind ◽  
A.-M. Svensson ◽  
M. Kosiborod ◽  
S. Gudbjörnsdottir ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Blood Pressure Level ◽  
Population Based ◽  
Case Control ◽  
Pressure Level ◽  
Control Study
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