Non‐severe hypoglycaemia is associated with weight gain in patients with type 1 diabetes: Results from the Diabetes Control and Complication Trial

2018 ◽  
Vol 20 (5) ◽  
pp. 1289-1292 ◽  
Author(s):  
Anisoara Bumbu ◽  
Abdul Moutairou ◽  
Odette Matar ◽  
Frédéric Fumeron ◽  
Gilberto Velho ◽  
...  
2008 ◽  
Vol 04 (01) ◽  
pp. 62 ◽  
Author(s):  
Jonathan Purnell

The Diabetes Control and Complications Trial (DCCT) was a prospective, randomised, controlled clinical trial that began in the 1980s and was carried out over a decade to determine whether intensive treatment aimed at maintaining blood glucose concentrations close to the normal range could decrease the frequency and severity of microvascular complications in patients with type 1 diabetes. The results showed that intensive therapy effectively delays the onset and progression of diabetic retinopathy, nephropathy, and neuropathy in patients with type 1 diabetes.1The side effects associated with intensive therapy were a nearly three-fold increased frequency of severe hypoglycaemia and greater weight gain. For the majority of patients with type 1 diabetes, the benefits of intensive therapy were considered to vastly outweigh these risks. However, the potential detrimental effects of weight gain, especially on macrovascular risks, are being revisited.


2018 ◽  
Author(s):  
Jan Idkowiak ◽  
Sabba Elhag ◽  
Vrinda Saraff ◽  
Renuka Dias ◽  
Timothy Barrett ◽  
...  

Author(s):  
David S. Greene ◽  
Nancy Dunavant King

Abstract There is increasing evidence of specific medical and psychological benefits associated with humor within diabetes populations. The benefits of maintaining good diabetes control are also well established. The more general relationship between humor and diabetes control however remains unexplored. The purpose of this study was to examine if there was a difference between people with diabetes with an A1C ≤ 6.99% versus those ≥7.0% on four disparate types of humor. The sample consisted of 284 participants, 65.5% with type 1 diabetes, 68.3% female, 89.1% Caucasian, and 68.7% college educated. Participants completed the Humor Styles Questionnaire (HSQ) and were divided into two groups, A1C ≤ 6.99% and A1C ≥ 7.0%. The A1C ≤ 6.99% group scored significantly higher on both types of positive humor, affiliative humor (P < 0.01) and self-enhancing humor (P < 0.05). There was no significant difference between participants on either type of negative humor, aggressive humor (P > 0.05) or self-defeating humor (P > 0.05). Results indicate that good control (A1C ≤ 6.99%) is associated with positive humor. These findings provide evidence that there is an association between American Diabetes Association recommended levels of control and positive humor styles. Implications regarding positive humor and good diabetes control are discussed.


2021 ◽  
Vol 9 (1) ◽  
pp. e002035
Author(s):  
Merel M Ruissen ◽  
Hannah Regeer ◽  
Cyril P Landstra ◽  
Marielle Schroijen ◽  
Ingrid Jazet ◽  
...  

IntroductionLockdown measures have a profound effect on many aspects of daily life relevant for diabetes self-management. We assessed whether lockdown measures, in the context of the COVID-19 pandemic, differentially affect perceived stress, body weight, exercise and related this to glycemic control in people with type 1 and type 2 diabetes.Research design and methodsWe performed a short-term observational cohort study at the Leiden University Medical Center. People with type 1 and type 2 diabetes ≥18 years were eligible to participate. Participants filled out online questionnaires, sent in blood for hemoglobin A1c (HbA1c) analysis and shared data of their flash or continuous glucose sensors. HbA1c during the lockdown was compared with the last known HbA1c before the lockdown.ResultsIn total, 435 people were included (type 1 diabetes n=280, type 2 diabetes n=155). An increase in perceived stress and anxiety, weight gain and less exercise was observed in both groups. There was improvement in glycemic control in the group with the highest HbA1c tertile (type 1 diabetes: −0.39% (−4.3 mmol/mol) (p<0.0001 and type 2 diabetes: −0.62% (−6.8 mmol/mol) (p=0.0036). Perceived stress was associated with difficulty with glycemic control (p<0.0001).ConclusionsAn increase in perceived stress and anxiety, weight gain and less exercise but no deterioration of glycemic control occurs in both people with relatively well-controlled type 1 and type 2 diabetes during short-term lockdown measures. As perceived stress showed to be associated with glycemic control, this provides opportunities for healthcare professionals to put more emphasis on psychological aspects during diabetes care consultations.


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