Elevated liver enzymes and comorbidities in type 2 diabetes: Multicenter analysis of 51,645 patients of the DPV database

2021 ◽  
Author(s):  
Svenja Meyhöfer ◽  
Alexander J. Eckert ◽  
Michael Hummel ◽  
Markus Laimer ◽  
Michael Roden ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Elevated Liver Enzymes ◽  
Multicenter Analysis

Elevated Liver Enzymes and Comorbidities in Type 2 Diabetes: A Population-Based Multicenter Analysis of 51,645 Patients of the DPV Database

2021 ◽  
Author(s):  
Svenja Meyhöfer ◽  
Alexander J. Eckert ◽  
Michael Hummel ◽  
Markus Laimer ◽  
Michael Roden ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Population Based ◽  
Elevated Liver Enzymes ◽  
Multicenter Analysis

scholarly journals Safety and efficacy of liraglutide in patients with type 2 diabetes with elevated liver enzymes: individual patient data meta-analysis of the LEAD programme

The Lancet ◽  
2013 ◽  
Vol 381 ◽  
pp. S20 ◽  
Author(s):  
MJ Armstrong ◽  
DD Houlihan ◽  
IA Rowe ◽  
WHO Clausen ◽  
B Elbrønd ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Patient Data ◽  
Safety And Efficacy ◽  
Elevated Liver Enzymes

scholarly journals Elevated Liver Enzymes in Patients with Type 2 Diabetes Mellitus and Non-alcoholic Fatty Liver Disease

Cureus ◽  
2018 ◽  
Author(s):  
Amrendra Mandal ◽  
Bikash Bhattarai ◽  
Paritosh Kafle ◽  
Mazin Khalid ◽  
Saikiran K Jonnadula ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Liver Disease ◽  
Fatty Liver Disease ◽  
Liver Enzymes ◽  
Alcoholic Fatty Liver ◽  
Elevated Liver Enzymes ◽  
Alcoholic Fatty Liver Disease

Increased Risk of Type 2 Diabetes in Subjects with Both Elevated Liver Enzymes and Ultrasonographically Diagnosed Nonalcoholic Fatty Liver Disease: A 4-year Longitudinal Study

2013 ◽  
Vol 44 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Ji Hun Choi ◽  
Eun Jung Rhee ◽  
Ji Cheol Bae ◽  
Se Eun Park ◽  
Cheol Young Park ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Disease ◽  
Longitudinal Study ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Enzymes ◽  
Nonalcoholic Fatty Liver ◽  
Elevated Liver Enzymes ◽  
Increased Risk

Benefits of exenatide on obesity and non-alcoholic fatty liver disease with elevated liver enzymes in patients with type 2 diabetes

2014 ◽  
Vol 30 (6) ◽  
pp. 521-529 ◽  
Author(s):  
Ning Shao ◽  
Hong Yu Kuang ◽  
Ming Hao ◽  
Xin Yuan Gao ◽  
Wen Jian Lin ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Enzymes ◽  
Alcoholic Fatty Liver ◽  
Elevated Liver Enzymes ◽  
Alcoholic Fatty Liver Disease

scholarly journals Assessment of Hepatic Steatosis and Fibrosis in Egyptian Patients with Type 2 Diabetes Mellitus

2021 ◽  
pp. 144-151
Author(s):  
Eman Basiouny ◽  
Faiza Lashin ◽  
Manal Hamisa ◽  
Amal Selim
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Hepatic Steatosis ◽  
Liver Enzymes ◽  
Early Management ◽  
Elevated Liver Enzymes

Aims: To assess hepatic steatosis and fibrosis in patients of type 2 diabetes mellitus (T2DM), their possible risk factors and their association with metabolic syndrome and micro or macro-albuminuria. Study Design: Cross sectional study. Place and Duration of Study: Outpatient Clinic of Diabetes, Metabolism and Endocrinology Unit in internal medicine department, Tanta University, Egypt in a period between September 2019 to March 2020. Methodology: We included 200 patients had a diagnosis of T2DM according to American Diabetes Association criteria. Then patients were assessed for presence of hepatic steatosis and fibrosis using fibroscan and we used liver stiffness measurements (LSMs, as a measure of fibrosis) and controlled attenuation parameter (CAP, as a measure of steatosis) and routine laboratory data were done to rule out possible risk factors. Results: 98.5% of participants had hepatic steatosis and 53.5% of participants had hepatic fibrosis. Those patients had longer duration of DM, higher BMI, bad control of T2DM, higher lipid profile values, association with metabolic syndrome, micro and macro-albuminuria and non-significantly elevated liver enzymes. Conclusion: Hepatic steatosis and fibrosis are highly prevalent in patients with T2DM, incidence of hepatic steatosis and fibrosis is positively correlated with longer duration of DM, higher BMI, bad control of DM, dyslipidemia, presence of metabolic syndrome, diabetic nephropathy, weakly correlated with liver enzymes. TE is an accurate and non-invasive tool to be used in screening for hepatic steatosis and fibrosis ,so we recommend screening for hepatic steatosis and fibrosis using fibroscan to help in early management and prevent its progression into liver cirrhosis.

scholarly journals Prevalence of elevated liver enzymes and its relationship with type 2 diabetes mellitus in North Indian adults

2021 ◽  
pp. 100130
Author(s):  
Sana Alam ◽  
Alok Raghav ◽  
Alisha Reyaz ◽  
Akif Ahsan ◽  
Ashok Kumar Ahirwar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Liver Enzymes ◽  
Elevated Liver Enzymes

scholarly journals Prevalence of elevated liver enzymes and its association with type 2 diabetes: A cross‐sectional study in Bangladeshi adults

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Shiful Islam ◽  
Sadaqur Rahman ◽  
Tangigul Haque ◽  
Abu Hasan Sumon ◽  
AZ Mahbub Ahmed ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elevated Liver Enzymes

scholarly journals Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver enzymes: individual patient data meta-analysis of the LEAD program

2012 ◽  
Vol 37 (2) ◽  
pp. 234-242 ◽  
Author(s):  
M. J. Armstrong ◽  
D. D. Houlihan ◽  
I. A. Rowe ◽  
W. H. O. Clausen ◽  
B. Elbrønd ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Patient Data ◽  
Safety And Efficacy ◽  
Elevated Liver Enzymes

scholarly journals Study Comparing the Liver Enzymes in Hypertensive and Normotensive Patients with Type 2 Diabetes

2021 ◽  
Vol 8 (7) ◽  
pp. 207-211
Author(s):  
Rishad Ahmed
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Liver Enzymes ◽  
Good Control ◽  
Diabetic Patients ◽  
Uncontrolled Diabetes ◽  
Elevated Liver Enzymes ◽  
Patients With Diabetes ◽  
Altered Liver

Objective: There were few clinical trials which indicate altered liver biochemical findings in diabetic patients, but through investigation to compare the liver enzymes in-between hypertensive and normotensive patients with type 2 diabetes was not evaluated. Thus main objective of current study was to compare the liver enzymes in hypertensive and normotensive patients with type 2 diabetes. Materials and Methods: This was a retrospective observational study conducted in a tertiary medical teaching hospital in Kolkata. Hospital OPD reports and patients clinical case records were used to fetch the required data in a predesigned clinical record pro forma. Result: Total 180 patients were participated in this observational retrospective trial where 33% patient were normotensive but having T2DM and 67% patients were hypertensive with T2DM. There were no statistically significant differences between the study variables among both the groups. However elevated level of GGT, ALT and AST were observed in T2DM normotensive patients as compare to T2DM hypertensive patients. abnormal liver functions were recorded in patients with uncontrolled diabetes as compared to patients with good control (p<0.05). Conclusion: The current study concluded that elevated liver enzymes like bilirubin, GGT, SGOT and SGPT were common among diabetes mellitus patients and comparable with patients with hypertensive as well as normotensive patients with diabetes mellitus. Keywords: Liver enzymes, T2DM, hypertension.

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