Oral treatment with/without topical treatment vs topical treatment alone in Malassezia Folliculitis patients: A systematic review and meta‐analysis

2020 ◽  
Vol 33 (3) ◽  
Author(s):  
Nikolaos Chaitidis ◽  
Charalampos Festas ◽  
Ioanna Aritzi ◽  
Maria Kyriazopoulou
Keyword(s):  
Systematic Review ◽  
Topical Treatment ◽  
Oral Treatment ◽  
Meta Analysis ◽  
Malassezia Folliculitis

scholarly journals Oral Fluoroquinolone or Trimethoprim-Sulfamethoxazole vs ß-Lactams as Step-Down Therapy for Enterobacteriaceae Bacteremia: Systematic Review and Meta-analysis

2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Chitra Punjabi ◽  
Vivian Tien ◽  
Lina Meng ◽  
Stan Deresinski ◽  
Marisa Holubar
Keyword(s):  
Systematic Review ◽  
Oral Treatment ◽  
Meta Analysis ◽  
Published Data ◽  
All Cause Mortality ◽  
Dosing Regimens ◽  
Step Down ◽  
Selection Of ◽  
Infection Recurrence

Abstract Background Using published data, we sought to compare outcomes in patients transitioned to either oral fluoroquinolones (FQs) or trimethoprim-sulfamethoxazole (TMP-SMX) vs ß-lactams (BLs) after an initial intravenous (IV) course for gram-negative rod (GNR) bacteremia. Methods We conducted a systematic review of PubMed and EMBASE and published IDWeek abstracts. We included studies that reported all-cause mortality and/or infection recurrence in patients transitioned to oral FQ/TMP-SMX and BLs. Results Eight retrospective studies met inclusion criteria with data for 2289 patients, of whom 65% were transitioned to oral FQs, 7.7% to TMP-SMX, and 27.2% to BLs. Follow-up periods ranged from 21 to 90 days. All-cause mortality was not significantly different between patients transitioned to either FQ/TMP-SMX or BLs (odds ratio [OR], 1.13; 95% confidence interval [CI], 0.69–1.87). Overall recurrence of infection, either bacteremia or the primary site, occurred more frequently in patients transitioned to oral BLs vs FQs (OR, 2.05; 95% CI, 1.17–3.61). Analysis limited to recurrent bacteremia was similarly suggestive, although limited by small numbers (OR, 2.15; 95% CI, 0.93–4.99). However, based on known pharmacokinetics/pharmacodynamics, prescribed ß-lactam dosing regimens were frequently suboptimal. Conclusions In the step-down IV to oral treatment of GNR bacteremia, we found insufficient data regarding outcomes after oral TMP-SMX; however, selection of an FQ over commonly utilized ß-lactam regimens may reduce chances of infection recurrence. Although this may be a class effect, it may simply be the result of inadequate dosing of ß-lactams. Additional investigations are warranted to determine outcomes with TMP-SMX and optimized oral ß-lactam dosing regimens.

Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: A systematic review and meta-analysis

2015 ◽  
Vol 72 (6) ◽  
pp. 992-1002 ◽  
Author(s):  
Laureline Legendre ◽  
Thomas Barnetche ◽  
Juliette Mazereeuw-Hautier ◽  
Nicolas Meyer ◽  
Dedee Murrell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Topical Treatment ◽  
Meta Analysis

scholarly journals A Systematic Review and Comprehensive Critical Analysis Examining the Use of Prednisolone for the Treatment of Mild to Moderate Croup

2017 ◽  
Vol 11 (1) ◽  
pp. 241-261
Author(s):  
Anna Catherine Elliott ◽  
Graham R. Williamson
Keyword(s):  
Systematic Review ◽  
Single Dose ◽  
Systematic Reviews ◽  
Cost Benefit Analysis ◽  
Oral Treatment ◽  
Meta Analysis ◽  
Cost Benefit ◽  
Oral Prednisolone ◽  
Cochrane Library ◽  
Randomised Controlled

Background:Many randomised control trials and systematic reviews have examined the benefits of glucocorticoids for the treatment of croup in children, but they have reported mainly on dexamethasone as an oral treatment for croup. No systematic reviews have examined prednisolone alone.Aim:To determine in a systematic review of the literature whether a single dose of oral prednisolone is as effective as a single dose of dexamethasone for reducing croup symptoms in children.Search Strategy:A detailed search was conducted on the following databases: CINAHL, MEDLINE EBSCO, MEDLINE, OVID, PubMed, The Cochrane Library, ProQuest, EMBASE, JBI, Sum search, and OpenGrey. Study authors were contacted.Selection Criteria:Randomised Controlled Trials, clinical trials or chart reviews which examined children with croup who were treated with prednisolone alone, or when prednisolone was compared to a dexamethasone treatment and the effectiveness of the intervention was objectively measured using croup scores and re-attendance as primary outcomes.Data Collection and Analysis:Following PRISMA guidelines for systematic reviews, relevant studies were identified. Scores were graded agreed by two independent reviewers using QualSyst.Main Results:Four studies met the inclusion criteria, but were too heterogeneous to combine in statistical meta-analysis. The result suggests that although prednisolone appears as effective as dexamethasone when first given, it is less so for preventing re-presentation. Trial sample sizes were small, making firm conclusions difficult, however, a second dose of prednisolone the following day may be useful. More research including cost-benefit analysis is needed to examine the efficacy of prednisolone compared to dexamethasone.

The effects of oral treatment for systemic sclerosis related pulmonary arterial hypertension: A systematic review and meta-analysis

2020 ◽  
Vol 31 (1) ◽  
pp. 151-161 ◽  
Author(s):  
Yunxia Lei ◽  
Xiao Zhang ◽  
Haobo Lin ◽  
Yuan Feng ◽  
Jieying Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systemic Sclerosis ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Oral Treatment ◽  
Meta Analysis ◽  
Pulmonary Arterial

Occlusive versus neurotoxic agents for topical treatment of head lice infestation: A systematic review and meta‐analysis

2019 ◽  
Vol 37 (1) ◽  
pp. 86-92 ◽  
Author(s):  
Rowena Natividad S. Flores‐Genuino ◽  
Charissa Mia S. Gnilo ◽  
Belen L. Dofitas
Keyword(s):  
Systematic Review ◽  
Topical Treatment ◽  
Meta Analysis ◽  
Head Lice ◽  
Head Lice Infestation

Resina Draconis as a topical treatment for pressure ulcers: A systematic review and meta-analysis

2015 ◽  
Vol 23 (4) ◽  
pp. 565-574 ◽  
Author(s):  
Jiaqi Xu ◽  
Tian Xiong ◽  
Ying Yang ◽  
Jie Li ◽  
Jing Mao
Keyword(s):  
Systematic Review ◽  
Topical Treatment ◽  
Pressure Ulcers ◽  
Meta Analysis ◽  
Resina Draconis

Choosing the Most Efficacious and Safe Oral Treatment for Idiopathic Overactive Bladder: A Systematic Review and Network Meta-analysis

2021 ◽  
Author(s):  
Hadi Mostafaei ◽  
Hanieh Salehi-Pourmehr ◽  
Sandra Jilch ◽  
Greta Lisa Carlin ◽  
Keiichiro Mori ◽  
...  
Keyword(s):  
Systematic Review ◽  
Overactive Bladder ◽  
Oral Treatment ◽  
Meta Analysis

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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