scholarly journals SAP domain forms a flexible part of DNA aperture in Ku70/80

FEBS Journal ◽  
2021 ◽  
Author(s):  
Aleš Hnízda ◽  
Petr Tesina ◽  
Thanh‐Binh Nguyen ◽  
Zdeněk Kukačka ◽  
Lukas Kater ◽  
...  
Keyword(s):  
Author(s):  
Sanaz Bazaz Behbahani ◽  
Xiaobo Tan

In this paper, we propose a novel design for a pectoral fin joint of a robotic fish. This joint uses a flexible part to enable the rowing pectoral fin to feather passively and thus reduce the hydrodynamic drag in the recovery stroke. On the other hand, a mechanical stopper allows the fin to maintain its motion prescribed by the servomotor in the power stroke. The design results in net thrust even when the fin is actuated symmetrically for the power and recovery strokes. A dynamic model for this joint and for a pectoral fin-actuated robotic fish involving such joints is presented. The pectoral fin is modeled as a rigid plate connected to the servo arm through a pair of torsional spring and damper that describes the flexible joint. The hydrodynamic force on the fin is evaluated with blade element theory, where all three components of the force are considered due to the feathering degree of freedom of the fin. Experimental results on robotic fish prototype are provided to support the effectiveness of the design and the presented dynamic model. We utilize three different joints (with different sizes and different flexible materials), produced with a multi-material 3D printer, and measure the feathering angles of the joints and the forward swimming velocities of the robotic fish. Good match between the model predictions and experimental data is achieved, and the advantage of the proposed flexible joint over a rigid joint, where the power and recovery strokes have to be actuated at different speeds to produce thrust, is demonstrated.


2012 ◽  
Vol 562-564 ◽  
pp. 917-920
Author(s):  
Yao Hua Deng ◽  
Gui Xiong Liu

This paper discusses the FWP bending deformation processing computing problems. Using Rayleigh-Leeds method to solve the flexible part bending deformation. Designing flexible part bending deformation test function. Finding out the flexible part itself material characteristics, the relationship between Fz and deformation through satisfying FWP processing process of a flexible minimum potential energy conditions to work out the approximate solution of the flexible part bending deformation. Finally, think a rectangular flexible workpiece that made of polyurethane sponge as an experiment subject. The results show that the calculated results of the average of the relative deviation are only 6.85%. Proof that this bending deformation test functions satisfies the actual deformation calculation requirements.


1989 ◽  
Vol 86 (17) ◽  
pp. 6562-6566 ◽  
Author(s):  
M Matsumura ◽  
W J Becktel ◽  
M Levitt ◽  
B W Matthews

Four different disulfide bridges (linking positions 9-164, 21-142, 90-122, and 127-154) were introduced into a cysteine-free phage T4 lysozyme at sites suggested by theoretical calculations and computer modeling. The new cysteines spontaneously formed disulfide bonds on exposure to air in vitro. In all cases the oxidized (crosslinked) lysozyme was more stable than the corresponding reduced (noncrosslinked) enzyme toward thermal denaturation. Relative to wild-type lysozyme, the melting temperatures of the 9-164 and 21-142 disulfide mutants were increased by 6.4 degrees C and 11.0 degrees C, whereas the other two mutants were either less stable or equally stable. Measurement of the equilibrium constants for the reduction of the engineered disulfide bonds by dithiothreitol indicates that the less thermostable mutants tend to have a less favorable crosslink in the native structure. The two disulfide bridges that are most effective in increasing the stability of T4 lysozyme have, in common, a large loop size and a location that includes a flexible part of the molecule. The results suggest that stabilization due to the effect of the crosslink on the entropy of the unfolded polypeptide is offset by the strain energy associated with formation of the disulfide bond in the folded protein. The design of disulfide bridges is discussed in terms of protein flexibility.


2015 ◽  
Vol 14 (3-4) ◽  
Author(s):  
K Sadesh ◽  
PV Mohram ◽  
S Udhayakumar

<p>A part feeder intakes identical parts of arbitrary orientation and provides output in uniform orientation. A flexible feeder is capable of handling parts of several sizes. The two important modules of a flexible part feeder are (i) identification of part (ii) adjustments to accommodate the incoming part. This paper aims at first module i.e. developing a low cost part identification system using two proximity sensors and thereby eliminating the use of costlier vision systems. The proposed part identification system using two capacitive type proximity sensors was effective in identifying the size of incoming parts and the efficiency of the system was around 84.6%.</p>


2021 ◽  
Vol 12 (4) ◽  
Author(s):  
H Sydoruk ◽  

Abstract. The article summarizes the theoretical experience of studying the structural and semantic characteristics of scientific and technical terms and agricultural terms in particular. It has substantiated the fact that the agrarian sphere is experiencing a rapid emergence of terms-innovations that are quickly passing all stages of structural-semantic assimilation. A significant percentage of terms are formed as a result of rethinking their previous meanings, which leads to the emergence of so-called semantic terms. Analysis of structural and semantic features of agricultural terms showed that their formation occurs through derivation, terminologization of common vocabulary and assimilation of borrowings. The paper also analyzes examples of the functioning of English-language multicomponent clusters and the peculiarities of their translation. The purpose of research is to clarify the structural and semantic features of agricultural terminology, to identify and describe the processes of formation of one- and multi-component agricultural terms, to determine the main word-forming types of agricultural terminology. Results of research. Agrarian terminology, which is a set of words and stable phrases corresponding to the concepts functioning in this area (objects, phenomena and actions), is a mobile and flexible part of common vocabulary, and therefore requires systematization. The main carriers of these concepts are nouns, a certain number of verbs and adjectives which most serve as definitions in multicomponent clusters and are not independent. Word-forming means are mainly Latin-Greek morphemes, word stems and phrases. Depending on the participation of language in term formation, the terms of the agricultural sector are divided into three types: simple terms or word-terms; complex terms; terms-phrases or multicomponent clusters Agrarian terminology uses such ways of word formation as lexical-semantic, lexical-syntactic, morphological, abbreviation, and morphological-syntactic. Many commonly used lexical items acquire meanings inherent in the agricultural sector, becoming terms with a narrower meaning. Modern scientific literature on agricultural topics contains terms that have two or more meanings in this area, the clarification of which is only disclosed by the context. In translation, such ambiguity causes blurring of meaning, vagueness, substitution of terms and ultimately distortion of the content as a whole. It is important to consider the lexical and grammatical environment of the term. Due to the context, the following translation issues can be addressed: a) the word is used in its common or special narrow meaning; b) the choice of one of several meanings of a polysemous term in a particular context. From agrarian vocabulary, terminological units move into colloquial language, sometimes becoming jargons or terminoids that function in limited areas of engineering and technology, forming a layer of stylized new scientific and technical terms. Professional slang is usually short, expressive and to some extent stylistically colored. The most successful of them are fixed in the terminology system over time and receive official recognition in a certain subject area, being fixed in dictionaries, and some pass to other areas and into the common language. Specifics of functioning the terminological combinations require appropriate methods of their translation, among which there are a few main ones: literal translation of lexical units is carried out with the help of calque; replacement of parts of speech; explanatory translation of terms; translation with word order changes, primarily in attributive group. Conclusions. Agro-biological terminology tends to be poly-variant in translation, polysemy and homonymy. In order to overcome the difficulties in translating professional texts, it is necessary to work more actively with special vocabulary, thoroughly study the issues of ambiguity, synonyms and antonyms, word formation and methods of translation. The above considerations open opportunities for the practical application of these methods of translation of agro-biological terminology, and for further creative search for the correct perception of professionally oriented texts.


2019 ◽  
pp. 141-164
Author(s):  
William M. Schniedewind

Advanced education was the most flexible part of the scribal curriculum. It could be tailored to the particular specialty of the scribe: the palace, the temple, commerce, military, etc. The advanced curriculum was often taken from other spheres, such as temple hymns or rituals, and used for scribal study (much like the Gettysburg Address or the “Star-Spangled Banner” might be reused as part of a school curriculum). There is evidence of cuneiform literature including Gilgamesh, Adapa, and law codes like Hammurabi that have been excavated in the southern Levant dating to the second millennium BCE. This provides a tangible vector of transmission for these traditions into the early alphabetic scribal tradition.


Author(s):  
Michel Joël Tchatchueng Kammegne ◽  
Yvan Tondji ◽  
Ruxandra Mihaela Botez ◽  
Lucian Teodor Grigorie ◽  
Mahmoud Mamou ◽  
...  

A morphing wing can improve the aircraft aerodynamic performance by changing the wing airfoil depending on the flight conditions. In this paper, a new control methodology is presented for a morphing wing demonstrator tested in a subsonic wind tunnel in the open-loop configuration. Actuators integrated inside the wing are used to modify the flexible structure, which is an integral part of the wing. In this project, the actuators are made in-house and controlled with logic control, which is developed within the main frame of this work. The characterization of the flow (laminar or turbulent) over the wing is obtained starting from the pressure signals measured over the flexible part of the wing (upper surface). The signals are acquired by using some pressure sensors (Kulite sensors) incorporated in this flexible part of the wing upper surface. The technique used to collect Kulite pressure data and the post-processing methodology are explained. The recorded pressure data are sometimes subjected to noise, which is filtered before being processed. The standard deviation and power spectrum visualization of the pressure data approaches are used to evaluate the quality of the flow over the wing and estimate the transition point position in the area monitored by the Kulite sensors. In addition, infrared thermography visualization is implemented to observe the transition region over the entire wing upper surface, and to validate the methodology applied to the pressure data in this way. The demonstrator measures 1.5 m chordwise and 1.5 m spanwise. Four miniature actuators fixed on two actuation lines are used to morph the wing. The wing is also equipped with a rigid aileron. The experimental aerodynamic results obtained after post processing validate the numerical prediction for the transition location.


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