Impact of Depression and Anxiety Symptoms on Patient‐Reported Outcomes in Patients With Migraine: Results From the American Registry for Migraine Research (ARMR)

2020 ◽  
Vol 60 (9) ◽  
pp. 1910-1919 ◽  
Author(s):  
Talia A. Pearl ◽  
Gina Dumkrieger ◽  
Catherine D. Chong ◽  
David W. Dodick ◽  
Todd J. Schwedt
Keyword(s):  
Patient Reported Outcomes ◽  
Anxiety Symptoms ◽  
Depression And Anxiety ◽  
Patient Reported

scholarly journals Determinants of patient-reported outcome trajectories and symptomatic recovery in Improving Access to Psychological Therapies (IAPT) services

2021 ◽  
pp. 1-10
Author(s):  
Jan Stochl ◽  
Emma Soneson ◽  
Freya Stuart ◽  
Jessica Fritz ◽  
Annabel E. L. Walsh ◽  
...  
Keyword(s):  
Symptom Severity ◽  
Severe Depression ◽  
Anxiety Symptoms ◽  
Rate Of Change ◽  
Depression And Anxiety ◽  
Rapid Improvement ◽  
Baseline Severity ◽  
Psychological Therapies ◽  
Patient Reported ◽  
Functionally Impaired

Abstract Background Despite evidence for the general effectiveness of psychological therapies, there exists substantial heterogeneity in patient outcomes. We aimed to identify factors associated with baseline severity of depression and anxiety symptoms, rate of symptomatic change over the course of therapy, and symptomatic recovery in a primary mental health care setting. Methods Using data from a service evaluation involving 35 527 patients in England's psychological and wellbeing [Improving Access to Psychological Therapies (IAPT)] services, we applied latent growth models to explore which routinely-collected sociodemographic, clinical, and therapeutic variables were associated with baseline symptom severity and rate of symptomatic change. We used a multilevel logit model to determine variables associated with symptomatic recovery. Results Being female, younger, more functionally impaired, and more socioeconomically disadvantaged was associated with higher baseline severity of both depression and anxiety symptoms. Being older, less functionally impaired, and having more severe baseline symptomatology was associated with more rapid improvement of both depression and anxiety symptoms (male gender and greater socioeconomic disadvantage were further associated with rate of change for depression only). Therapy intensity and appointment frequency seemed to have no correlation with rate of symptomatic improvement. Patients with lower baseline symptom severity, less functional impairment, and older age had a greater likelihood of achieving symptomatic recovery (as defined by IAPT criteria). Conclusions We must continue to investigate how best to tailor psychotherapeutic interventions to fit patients’ needs. Patients who begin therapy with more severe depression and/or anxiety symptoms and poorer functioning merit special attention, as these characteristics may negatively impact recovery.

scholarly journals An Increase in Mediterranean Dietary Score, Through SunGold® Kiwifruit, Potentially Improves Mental Wellbeing

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 401-401
Author(s):  
Huyen Tran Diep Pham ◽  
Catherine Wall ◽  
Simone Bayer ◽  
Paul Blatchford ◽  
Richard Gearry
Keyword(s):  
Mediterranean Diet ◽  
Dietary Pattern ◽  
Anxiety Symptoms ◽  
Mental Wellbeing ◽  
P Value ◽  
The Novel ◽  
Depression And Anxiety ◽  
Patient Reported ◽  
Habitual Diet ◽  
The Mediterranean

Abstract Objectives Research suggests that high adherence to Mediterranean dietary pattern significantly improve depression and anxiety symptoms. Thus, the objective was to utilize the novel and validated Mediterranean Diet Serving Score (MDSS) method to assess habitual intake of a study cohort, which evaluated SunGold® kiwifruit and psyllium powder interventions, against the Mediterranean diet recommendations. The link between the MDSS and mental wellbeing were then explored. Methods The project's data was collected during the randomized cross-over controlled trial Christchurch Irritable Bowel Syndrome cohort to investigate mechanisms for gut relief and improved transit - Psyllium and Kiwifruit translation study (COMFORT-PSYKI). Participants were randomized into two interventions: psyllium powder or SunGold® kiwifruit. MDSS was evaluated from dietary records with the recommended serving sizes obtained from the New Zealand Food Composition Database. Depression and anxiety score were collected through the Patient-Reported Outcomes Measurement Information System (PROMIS) survey. Results The habitual diet of the participants (n = 45, mean age 39 ± 15 years) had a low MDSS (mean 5.04 ± 2.38, out of 24 points) when compared against the Mediterranean pyramid recommendations. Their MDSS improved with daily consumption of two SunGold® kiwifruit significantly (mean 6.27 ± 2.81, P-value < 0.05) compared to Psyllium powder (mean 5.58 ± 3.05, P-value = 0.906). Moreover, mean depression (42.33 ± 6.08, P-value) and anxiety (43.24 ± 7.71) scores were reported lower with the higher MDSS of SunGold® intervention at 42.33 ± 6.08 (P-value = 0.315) and 43.24 ± 7.71 (P-value = 0.906), respectively. Conclusions This project suggests that consuming two SunGold® kiwifruit daily could significantly enhance participants’ habitual diet to meet the Mediterranean diet recommendations and healthy eating guideline. This improvement could potentially lead to a reduction in depression and anxiety symptoms. The feasibility of the novel MDSS method was also demonstrated to be suitable for dietary pattern assessment among adult New Zealanders. Future investigations are warranted to confirm the association between dietary pattern and mental wellbeing. Funding Sources This project was funded by Zespri International Limited (Zespri) and Callaghan Innovation R&D Experience Grant.

scholarly journals Changes in patients’ depression and anxiety associated with changes in patient-reported outcomes after spine surgery

2020 ◽  
Vol 32 (6) ◽  
pp. 871-890 ◽  
Author(s):  
Rafa Rahman ◽  
Alvaro Ibaseta ◽  
Jay S. Reidler ◽  
Nicholas S. Andrade ◽  
Richard L. Skolasky ◽  
...  
Keyword(s):  
Sleep Disturbance ◽  
Physical Function ◽  
Spine Surgery ◽  
Patient Reported Outcomes ◽  
Social Roles ◽  
Deformity Correction ◽  
Depression And Anxiety ◽  
Postoperative Changes ◽  
Patient Reported ◽  
Persistent Depression

OBJECTIVEThe authors conducted a study to analyze associations between changes in depression/anxiety before and 12 months after spine surgery, as well as changes in scores using the Patient-Reported Outcomes Measurement Information System (PROMIS) at the same time points.METHODSPreoperatively and 12 months postoperatively, the authors assessed PROMIS scores for depression, anxiety, pain, physical function, sleep disturbance, and satisfaction with participation in social roles among 206 patients undergoing spine surgery for deformity correction or degenerative disease. Patients were stratified according to preoperative/postoperative changes in depression and anxiety, which were categorized as persistent, improved, newly developed postoperatively, or absent. Multivariate regression was used to control for confounders and to compare changes in patient-reported outcomes (PROs).RESULTSFifty patients (24%) had preoperative depression, which improved in 26 (52%). Ninety-four patients (46%) had preoperative anxiety, which improved in 70 (74%). Household income was the only preoperative characteristic that differed significantly between patients whose depression persisted and those whose depression improved. Compared with the no-depression group, patients with persistent depression had less improvement in all 4 domains, and patients with postoperatively developed depression had less improvement in pain, physical function, and satisfaction with social roles. Compared with the group of patients with postoperatively improved depression, patients with persistent depression had less improvement in pain and physical function, and patients with postoperatively developed depression had less improvement in pain. Compared with patients with no anxiety, those with persistent anxiety had less improvement in physical function, sleep disturbance, and satisfaction with social roles, and patients with postoperatively developed anxiety had less improvement in pain, physical function, and satisfaction with social roles. Compared with patients with postoperatively improved anxiety, patients with persistent anxiety had less improvement in pain, physical function, and satisfaction with social roles, and those with postoperatively developed anxiety had less improvement in pain, physical function, and satisfaction with social roles. All reported differences were significant at p < 0.05.CONCLUSIONSMany spine surgery patients experienced postoperative improvements in depression/anxiety. Improvements in 12-month PROs were smaller among patients with persistent or postoperatively developed depression/anxiety compared with patients who had no depression or anxiety before or after surgery and those whose depression/anxiety improved after surgery. Postoperative changes in depression/anxiety may have a greater effect than preoperative depression/anxiety on changes in PROs after spine surgery. Addressing the mental health of spine surgery patients may improve postoperative PROs.■ CLASSIFICATION OF EVIDENCE Type of question: causation; study design: prospective cohort study; evidence: class III.

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