Water dispersibility of the β‐carotene source and its effect on the physical, thermal, and in vitro release properties of an inclusion complex

Author(s):  
Floirendo P. Flores ◽  
Fanbin Kong
2008 ◽  
Vol 43 (3) ◽  
pp. 464-470 ◽  
Author(s):  
Gladys E. Granero ◽  
Marcos M. Maitre ◽  
Claudia Garnero ◽  
Marcela R. Longhi

2007 ◽  
Vol 342-343 ◽  
pp. 489-492 ◽  
Author(s):  
Hullathy Subban Ganapathy ◽  
Min Hee Woo ◽  
Yeong Soon Gal ◽  
Kwon Taek Lim

The inclusion complex of CO2-soluble peracetylated-β-cyclodextrin (PAc-β- CD), heptakis(2,3,6-tri-O-acetyl)-β-cyclodextrin, and highly water-soluble drug captopril, was prepared by a chemical solvent-free method using supercritical carbon dioxide. The captopril-PAc-β-CD inclusion complex was further confirmed by DSC and XRD studies. In- vitro release of captopril from an oily suspension confirmed that the dissolution rate of captopril was much retarded from the inclusion complex as a result of the hydrophobic properties of PAc-β-CD.


2011 ◽  
Vol 56 (2) ◽  
pp. 137-143 ◽  
Author(s):  
Wagner L. Priamo ◽  
Alana M. de Cezaro ◽  
Stéphani C. Benetti ◽  
J. Vladimir Oliveira ◽  
Sandra R.S. Ferreira

2015 ◽  
Vol 63 (50) ◽  
pp. 10831-10837 ◽  
Author(s):  
Jiang Yi ◽  
Fang Zhong ◽  
Yuzhu Zhang ◽  
Wallace Yokoyama ◽  
Liqing Zhao

LWT ◽  
2014 ◽  
Vol 59 (2) ◽  
pp. 867-873 ◽  
Author(s):  
Zhanqun Hou ◽  
Yuwei Liu ◽  
Fei Lei ◽  
Yanxiang Gao

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Nunthiya Deepuppha ◽  
Sudarat Khadsai ◽  
Boonjira Rutnakornpituk ◽  
Uthai Wichai ◽  
Metha Rutnakornpituk

pH- and thermoresponsive nanocomposite composed of poly(N-acryloyl glycine) (PNAG) matrix and magnetite nanoparticle (MNP) was synthesized and then used for drug controlled release application. The effects of crosslinkers, e.g., ethylenediamine and tris(2-aminoethyl)amine, and their concentrations (1 and 10 mol%) on the size, magnetic separation ability, and water dispersibility of the nanocomposite were investigated. The nanocomposite crosslinked with tris(2-aminoethyl)amine (size ranging between 50 and 150 nm in diameter) can be rapidly separated by a magnet while maintaining its good dispersibility in water. It can respond to the pH and temperature change as indicated by the changes in its zeta potential and hydrodynamic size. From the in vitro release study, theophylline as a model drug was rapidly released when the pH changed from neutral to acidic/basic conditions or when increasing the temperature from 10°C to 37°C. This novel nanocomposite showed a potential application as a magnetically guidable vehicle for drug controlled release with pH- and thermotriggered mechanism.


2003 ◽  
Vol 20 (5) ◽  
pp. 569-579 ◽  
Author(s):  
S.-A. Seo ◽  
G. Khang ◽  
J. M. Rhee ◽  
J. Kim ◽  
H. B. Lee

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