Infant growth during the first year of life following a pregnancy lifestyle intervention in routine care—Findings from the cluster‐randomised
            GeliS
            trial

Lifestyle interventions during pregnancy were shown to beneficially influence maternal dietary behaviour and physical activity, but their effect on health behaviour after delivery is unclear. The objective of this secondary analysis was to investigate the sustained effect of a lifestyle intervention in routine care on maternal health behaviour during the first year postpartum. The cluster-randomised controlled “Healthy living in pregnancy” (GeliS) study included 2286 pregnant women. Data on maternal health behaviour were collected at 6–8 weeks (T1pp) and one year postpartum (T2pp) using validated questionnaires. The intervention group showed a lower mean intake of fast food (T1pp: p = 0.016; T2pp: p < 0.001) and soft drinks (T1pp: p < 0.001), a higher mean intake of vegetables (T2pp: p = 0.015) and was more likely to use healthy oils for meal preparation than the control group. Dietary quality rated by a healthy eating index was higher in the intervention group (T1pp: p = 0.093; T2pp: p = 0.043). There were minor trends towards an intervention effect on physical activity behaviour. The proportion of smokers was lower in the intervention group (p < 0.001, both time points). The lifestyle intervention within routine care modestly improved maternal postpartum dietary and smoking behaviours.

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Leptin levels at birth and infant growth: the EPOCH study

Journal of Developmental Origins of Health and Disease ◽

10.1017/s204017441400021x ◽

2014 ◽

Vol 5 (3) ◽

pp. 214-218 ◽

Cited By ~ 16

Author(s):

J. L. Kaar ◽

J. T. Brinton ◽

T. Crume ◽

R. F. Hamman ◽

D. H. Glueck ◽

...

Keyword(s):

Cord Blood ◽

Perinatal Outcomes ◽

Epidemiological Studies ◽

In Utero ◽

Feedback Mechanism ◽

Infant Growth ◽

Sufficient Evidence ◽

First Year ◽

First Year Of Life ◽

Maternal Overweight

Objective: To examine the association of cord blood leptin with body mass index (BMI) growth velocity from birth to 12 months of age among infants exposed and not exposed to over-nutrition in utero (defined as maternal overweight/obesity or presence of gestational diabetes). Methods: 185 infants enrolled in the Exploring Perinatal Outcomes among Children study (76 exposed and 109 not exposed) had leptin and insulin measured in cord blood. Longitudinal weight and length measures in the first 12 months of life (average 4 per participant) obtained from medical records were used to compute BMI growth rates. Mixed models were used to examine associations of cord blood leptin with growth. Results: Compared with unexposed infants, those exposed had significantly higher cord blood insulin (8.64 v. 6.97 uU/ml, P<0.01) and leptin levels (8.89 v. 5.92 ng/ml, P=0.05) as well as increased birth weights (3438.04 v. 3306.89 g, P=0.04). There was an inverse relationship between cord leptin levels and BMI growth from birth to 12 months of age (P=0.005); however, exposure to over-nutrition in utero did not significantly modify this association (P=0.59). Conclusion: We provide support of a possible operational feedback mechanism by which lower cord blood leptin levels are associated with faster infant growth in the first year of life. Our data do not tend to support the hypothesis that this mechanism is altered in infants exposed to over-nutrition in utero; however our sample is too small to provide sufficient evidence. Larger epidemiological studies are needed to elucidate the mechanisms responsible for increased propensity for obesity in exposed offspring.

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Sodium Chloride Supplementation Is Not Routinely Performed in the Majority of German and Austrian Infants with Classic Salt-Wasting Congenital Adrenal Hyperplasia and Has No Effect on Linear Growth and Hydrocortisone or Fludrocortisone Dose

Hormone Research in Paediatrics ◽

10.1159/000481775 ◽

2017 ◽

Vol 89 (1) ◽

pp. 7-12 ◽

Cited By ~ 5

Author(s):

Walter Bonfig ◽

Friedhelm Roehl ◽

Stefan Riedl ◽

Jürgen Brämswig ◽

Annette Richter-Unruh ◽

...

Keyword(s):

Sodium Chloride ◽

Congenital Adrenal Hyperplasia ◽

Routine Care ◽

Sodium Content ◽

Adrenal Crisis ◽

First Year ◽

Adrenal Hyperplasia ◽

Salt Wasting ◽

First Year Of Life ◽

Oral Sodium

Introduction: Sodium chloride supplementation in salt-wasting congenital adrenal hyperplasia (CAH) is generally recommended in infants, but its implementation in routine care is very heterogeneous. Objective: To evaluate oral sodium chloride supplementation, growth, and hydrocortisone and fludrocortisone dose in infants with salt-wasting CAH due to 21-hydroxylase in 311 infants from the AQUAPE CAH database. Results: Of 358 patients with classic CAH born between 1999 and 2015, 311 patients had salt-wasting CAH (133 females, 178 males). Of these, 86 patients (27.7%) received oral sodium chloride supplementation in a mean dose of 0.9 ± 1.4 mmol/kg/day (excluding nutritional sodium content) during the first year of life. 225 patients (72.3%) were not treated with sodium chloride. The percentage of sodium chloride-supplemented patients rose from 15.2% in children born 1999–2004 to 37.5% in children born 2011–2015. Sodium chloride-supplemented and -unsupplemented infants did not significantly differ in hydrocortisone and fludrocortisone dose, target height-corrected height-SDS, and BMI-SDS during the first 2 years of life. Conclusion: In the AQUAPE CAH database, approximately one-third of infants with salt-wasting CAH receive sodium chloride supplementation. Sodium chloride supplementation is performed more frequently in recent years. However, salt supplementation had no influence on growth, daily fludrocortisone and hydrocortisone dose, and frequency of adrenal crisis.

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Infant Growth During the First Year of Life and Subsequent Hospitalization to 8 Years of Age

Epidemiology ◽

10.1097/ede.0b013e3181cd709e ◽

2010 ◽

Vol 21 (3) ◽

pp. 332-339 ◽

Cited By ~ 16

Author(s):

L. L. Hui ◽

C. Mary Schooling ◽

M. Y. Wong ◽

L. M. Ho ◽

T. H. Lam ◽

...

Keyword(s):

Infant Growth ◽

First Year ◽

First Year Of Life

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Poor maternal anthropometric status before conception is associated with a deleterious infant growth during the first year of life: a longitudinal preconceptional cohort

Pediatric Obesity ◽

10.1111/ijpo.12573 ◽

2019 ◽

Vol 15 (1) ◽

Cited By ~ 1

Author(s):

Gino Agbota ◽

Nadine Fievet ◽

Barbara Heude ◽

Manfred Accrombessi ◽

Urbain Ahouayito ◽

...

Keyword(s):

Infant Growth ◽

First Year ◽

First Year Of Life ◽

Anthropometric Status

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Correction To: Effects of a lifestyle intervention in routine care on prenatal physical activity – findings from the cluster-randomised GeliS trial

BMC Medical Education ◽

10.1186/s12909-019-1889-z ◽

2019 ◽

Vol 19 (1) ◽

Author(s):

Julia Hoffmann ◽

Julia Günther ◽

Kristina Geyer ◽

Lynne Stecher ◽

Kathrin Rauh ◽

...

Keyword(s):

Physical Activity ◽

Lifestyle Intervention ◽

Routine Care ◽

Cluster Randomised

Following publication of the original article [1], the author notified us about incorrectly formatted of Table 2 and Table 3.

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Association of antioxidant vitamins and oxidative stress levels in pregnancy with infant growth during the first year of life

Public Health Nutrition ◽

10.1017/s1368980007001322 ◽

2008 ◽

Vol 11 (10) ◽

pp. 998-1005 ◽

Cited By ~ 14

Author(s):

Juhee Hong ◽

Eun Ae Park ◽

Young-Ju Kim ◽

Hwa Young Lee ◽

Bo-Hyun Park ◽

...

Keyword(s):

Oxidative Stress ◽

Cohort Study ◽

Vitamin C ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Infant Growth ◽

First Year ◽

First Year Of Life ◽

And Oxidative Stress ◽

In Pregnancy

AbstractObjectiveWhereas there are numerous reports in the literature relating the impact of maternal nutritional status on subsequent birth outcome, much less is known about the long-term impact on infant growth after birth. Therefore, we conducted a prospective cohort study to investigate the association of maternal micronutrient status (vitamins A, C and E, folate) and oxidative stress status in pregnancy with infant growth during the first year of life.DesignProspective cohort study.SettingOutpatient clinic of obstetrics, Ewha Womans University Hospital, Seoul, South Korea.Subjects and methodsTwo groups were constructed for this study – the Ewha pregnancy cohort (n = 677) and the infant growth cohort comprising follow-up live newborns of all the recruited pregnant women (n = 317). Maternal serum vitamin and urinary oxidative stress levels were collected and infant weights and heights were measured at birth and at 6 and 12 months after birth.ResultsDivision of the subjects into folate-deficient and normal groups revealed that infant weight and height at 0, 6 and 12 months were adversely affected by folate deficiency. High maternal vitamin C was associated with increased infant weight and height at birth and after birth.ConclusionOur findings indicate the importance of preventing folate deficiency and supplementing vitamin C during pregnancy.

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Relationship of Weight Gain During Pregnancy to Birth Weight and Infant Growth and Development in the First Year of Life

Obstetrics and Gynecology ◽

10.1097/00006250-196803000-00021 ◽

1968 ◽

Vol 31 (3) ◽

pp. 417-423 ◽

Cited By ~ 72

Author(s):

JUDITH E. SINGER ◽

MILTON WESTPHAL ◽

KENNETH NISWANDER

Keyword(s):

Weight Gain ◽

Birth Weight ◽

Growth And Development ◽

Infant Growth ◽

First Year ◽

First Year Of Life ◽

Relationship Of ◽

Weight Gain During Pregnancy

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Maternal Diet Quality and Infant Growth Trajectories During the First Year of Life (OR35-07-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz048.or35-07-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Andrea Lopez-Cepero ◽

Lisa Nobel ◽

Tiffany Moore-Simas ◽

Milagros Rosal

Keyword(s):

Diet Quality ◽

Rapid Growth ◽

Maternal Diet ◽

Infant Growth ◽

Growth Trajectory ◽

Growth Trajectories ◽

First Year ◽

Lower Odds ◽

Trajectory Models ◽

First Year Of Life

Abstract Objectives To examine the association between maternal diet quality and infant weight for length growth trajectory during their first year of life. Methods Participants were singleton infant-mother pairs (N = 77) enrolled in the Pregnancy and Postpartum Observational Dietary Study. Mothers completed socio-demographics and dietary (24-hour recalls) assessments at 3 months postpartum. The Alternate Healthy Eating Index (aHEI) was calculated to measure maternal diet quality. Infant weight for length measures from birth to 12 months were abstracted from pediatric records. World Health Organization guidelines were used to calculate infants’ weight for length percentiles. Group-based trajectory analysis was done to identify subgroups of infants with similar growth profiles and to evaluate the association between maternal aHEI and infant's growth trajectory. Models were adjusted for maternal age, race, education and excessive gestational weight gain (GWG). Results Mothers’ mean age was 28 years ± 5.2; 27% were Latina, and 55% had some college education or more; 60% had experienced excessive GWG; and their average aHEI was 26.7 ± 7.5. Three infant growth trajectories were identified: a low and stable growth group (43.2%), a rapid growth group (33.5%), and a moderate growth group (23.3%). Maternal aHEI was significantly associated with lower odds of having their infant in the rapid growth group (OR = 0.83; P = 0.012), with each unit increase in aHEI score being associated with 17% lower odds of infant's rapid growth. Conclusions Trajectory models suggested three patterns of infant growth. Higher maternal diet quality was associated with lower odds of infant rapid growth. Future studies are needed to replicate these findings in larger cohorts and identify mediators of this association to prevent childhood obesity. Funding Sources CCTS (UL1TR001453), NCATS (UL1TR000161), NIMHD (1P60MD006912-02), CDC (U48-DP001933), NIGMS (R25GM113686-02), NHLBI (F30HL128012), and Canadian Institutes of Health Research (DFS-140394).

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