scholarly journals Differentiating impacts of non‐pharmaceutical interventions on non‐coronavirus disease‐2019 respiratory viral infections: Hospital‐based retrospective observational study in Taiwan

2021 ◽  
Author(s):  
Andrew Po‐Liang Chen ◽  
Isaac Yen‐Hao Chu ◽  
Mei‐Lin Yeh ◽  
Yin‐Yin Chen ◽  
Chia‐Lin Lee ◽  
...  
Keyword(s):  
Observational Study ◽  
Viral Infections ◽  
Retrospective Observational Study ◽  
Respiratory Viral Infections ◽  
Pharmaceutical Interventions

scholarly journals Differentiating Impacts of Non-Pharmaceutical Interventions on Non-Coronavirus-Disease-2019 Respiratory Viral Infections: Hospital-Based Retrospective Observational Study in Taiwan

2021 ◽  
Author(s):  
Po-Liang Chen ◽  
Isaac Yen-Hao Chu ◽  
Mei-Lin Yeh ◽  
Yin-Yin Chen ◽  
Chia-Lin Lee ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Observational Study ◽  
Pediatric Patients ◽  
Viral Infections ◽  
Respiratory Viruses ◽  
Influenza Viruses ◽  
Retrospective Observational Study ◽  
Enveloped Viruses ◽  
Respiratory Viral Infections ◽  
Pharmaceutical Interventions

Background Physical distancing and facemask use are worldwide recognized as effective non-pharmaceutical interventions (NPIs) against the coronavirus disease 2019 (COVID-19). Since January 2020, Taiwan has introduced both NPIs but their effectiveness on non-COVID-19 respiratory viruses (NCRVs) remain underexplored. Methods This retrospective observational study examined electronic records at a tertiary hospital in northern Taiwan from pre-COVID (January–December 2019) to post-COVID period (January–May 2020). Patients with respiratory syndromes were tested for both enveloped (e.g. influenza virus and seasonal coronavirus) and non-enveloped RVs (e.g. enterovirus and rhinovirus) using multiplex reverse-transcription polymerase chain reaction assays. Monthly positivity rates of NCRVs among adult and pediatric patients were analyzed with comparison between pre- and post-COVID periods. Results A total of 9693 patients underwent 12127 multiplex RT-PCR tests. The average positivity rate of NCRVs reduced by 11.2% (25.6% to 14.4%) after nationwide PHIs. Despite the COVID-19 pandemic, the most commonly identified enveloped and non-enveloped viruses were influenza virus and enterovirus/rhinovirus, respectively. Observed reduction in NCRV incidence was predominantly contributed by enveloped NCRVs including influenza viruses. We did not observe epidemiological impacts of NPIs on non-enveloped viruses but an increasing trend in enterovirus/rhinovirus test positivity rate among pediatric patients. Our data were validated using Taiwan’s national notification database. Conclusions Our frontline investigation suggests that the current NPIs in Taiwan might not effectively control the transmission of non-enveloped respiratory viruses, despite their protective effects against influenza and seasonal coronavirus. Hydrogen peroxide or chloride-based disinfectants should be integrated into national preventative strategies against respiratory viral infections in the post-COVID-19 era.

scholarly journals A Silver Lining? Fewer non-SARS-CoV-2 Respiratory Viruses during the COVID-19 Pandemic

2021 ◽  
Author(s):  
Zachary M Most ◽  
Michael Holcomb ◽  
Andrew R Jamieson ◽  
Trish M Perl
Keyword(s):  
Count Data ◽  
Viral Infections ◽  
Respiratory Viruses ◽  
Aggregate Level ◽  
Case Count ◽  
Health Initiatives ◽  
Respiratory Viral Infections ◽  
Public Health Initiatives ◽  
Silver Lining ◽  
Pharmaceutical Interventions

Abstract Non-pharmaceutical interventions (NPIs) have “flattened the curve” of the COVID-19 pandemic, however the effect of these interventions on other respiratory viruses is unknown. We used aggregate level case count data for eight respiratory viruses and compared the institutional and statewide case counts before and during the period that NPIs were active. We observed a 61% (IRR 0.39, 95% CI 0.37 to 0.41, P < 0.0001) decrease in non-SARS-CoV-2 respiratory viral infections when NPIs were implemented. This finding, if further verified, should guide future public health initiatives to mitigate viral epidemics.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

Chemokines in Respiratory Viral Infections: Focus on Their Diagnostic and Therapeutic Potential

2011 ◽  
Vol 31 (4) ◽  
pp. 341-356 ◽  
Author(s):  
Virginia Amanatidou ◽  
Apostolos Zaravinos ◽  
Stavros Apostolakis ◽  
Demetrios A. Spandidos
Keyword(s):  
Viral Infections ◽  
Therapeutic Potential ◽  
Respiratory Viral Infections

SYNDROME OF SYSTEMIC INFLAMMATORY RESPONSE IN PATIENTS WITH ACUTE RESPIRATORY VIRAL INFECTIONS OF CHILDREN

2017 ◽  
Vol 96 (4) ◽  
pp. 22-27 ◽  
Author(s):  
I. V. Babachenko ◽  
◽  
L. A. Alekseeva ◽  
O. M. Ibragimova ◽  
Т. V. Bessonova ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Viral Infections ◽  
Systemic Inflammatory Response ◽  
Respiratory Viral Infections
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