Clinical profile of mechanically ventilated COVID-19 patients: a retrospective observational study

Author(s):  
Prashant Nasa
2018 ◽  
Vol 5 (4) ◽  
pp. 1600 ◽  
Author(s):  
Rajkumar M. Meshram ◽  
Ashwini Patil

Background: Although, diphtheria is eliminated by many developed countries by effective immunization, still diphtheria   continues to be endemic in India and leading cause of morbidity and mortality, especially in areas in the border of the two states. The objective of the present study was to recognize the clinical profile, morbidity and mortality pattern of diphtheria and to study their immunization status as a retrospective observational study performed in pediatric wards and paediatric intensive care unit.Methods: The medical records were recovered from the case files, searching for cases diagnosed as diphtheria from the Medical Record Section and Statistical Service of the institute.  A pre-established protocol was formed after approval from institutional ethical committee. Case study   included suspected, probable and confirmed cases of diphtheria as per the WHO definition guidelines. All the relevant data and information regarding age, gender, residence, socioeconomic status, immunization status, clinical details, laboratory investigation, complications, and treatment provided, and outcome were recorded.Results: Amongst 47 patients, 55.32% were >5years and mean age was 6.46±3.08 years with no difference in sex distribution.  2(4.25%) patients were completely immunized, 27(57.45%) were partially immunized and 18(38.30%) were not immunized. An immunization rate was less in females as compared to males. All patients presented with fever and membrane in throat followed by throat pain 95.74%, enlarged/congested tonsils 80.85%, respiratory difficulty 68.08%, dysphagia 59.57% bull neck 48.94% and voice change 36.17%. Myocarditis was the commonest (42.55%) complication followed by palatal palsy (14.89%), polyneuropathy (8.51%), acute renal failure (4.25%) and DIC & shock (4.25%) were observed. Case fatality rate was 21.28%. Maximum numbers of cases were noted during the rainy season.Conclusions: Shifting of occurrence of diphtheria in the age group of 5-15 years suggest the need to improve and strengthen the immunization activity specially booster doses in the border districts as most of the cases were from areas at the border of two states.


Author(s):  
Deepak Karn

Aim: to determine the prevalence and clinical profile of patients presented with posterior fossa extra dural hematoma. Materials and Methods: The present retrospective observational study was conducted in the Department of Neurosurgery, SKMCH, Muzaffarpur, Bihar, India.  The records were retrospectively analyzed for clinical presentation, admission Glasgow Coma Scale (GCS), mode of injury, type of intervention and postoperative outcome. Outcomes were assessed on the basis of Glasgow Outcome Score (GOS) at the time of discharge and at 3 months Results: Of these 39 patients, 28 were males and 11 females. The mean age of patients was 29.21 years. 24 patients had GCS 13-15 at admission followed by 9 with GCS 9-12 and only 5 of them had GCS <9 at admission. Mean EDH volume was 28.7 ml. 36 patients were operated, 5 patients managed conservatively. Conclusion: The posterior fossa is an uncommon site for epidural haematomas. Due to the small volume of the posterior fossa and contained important structures mortality can be high if the haematoma is missed. Clinical progress is silent and slow, but the deterioration is sudden and quick to become fatal if not promptly treated. Early recognition is extremely important. Keywords: Extradural hematoma, Posteriors fossa, GCS, Trauma


Author(s):  
Neena Bhalodiya ◽  
Kerul J. Prajapati ◽  
Parth Hingol ◽  
Simple Bhadania

<p class="abstract"><strong>Background:</strong> The study aimed to assess the profile of various pathological conditions that present with nasal mass in Indian patients.</p><p class="abstract"><strong>Methods:</strong> This is a retrospective observational study of 43 patients of sinonasal masses who visited GMERS Medical College and Hospital, Sola, Ahmedabad, India during May 2017 to March 2020. The clinical profile of sinus or nasal masses were observed along with their radiological features on computed tomography scans of paranasal sinuses. The age and gender sub group were also assessed for distribution of these conditions. Most of the patients were managed with surgical techniques.  </p><p class="abstract"><strong>Results:</strong> Overall, clinical profile of 43 patients was observed. The clinicopathological examination aided by endoscopic and imaging studies revealed that 20 (46.5%) patients presented with the non-neoplastic masses and remaining were with neoplastic masses (53.5%). The overall M: F ratio was 1.5:1. Most of the patients belong to         11-30 years age group. The most common symptoms were mass in the nasal cavity and nasal discharge. Polyps were most common lesions seen (25.6%). Surgical intervention in the form of biopsy, excision of mass, functional endoscopic sinus surgery was performed in all patients.</p><p class="abstract"><strong>Conclusions:</strong> This study gives an insight into various lesions presenting as sinonasal masses and their clinical and pathological profile. Overall, surgical management in form of excision by endoscopic or external approach is effective modality of treatment supplemented with appropriate medical management.</p>


2011 ◽  
Vol 9 (3) ◽  
pp. 267-271 ◽  
Author(s):  
Mubashir Ali Khan ◽  
Abdul Majeed Dar ◽  
Nadeem Ulnazeer Kawoosa ◽  
Abdul Gani Ahangar ◽  
Ghulam Nabi Lone ◽  
...  

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