SEX HORMONE CONCENTRATIONS IN POST-MENOPAUSAL WOMEN RELATION TO OBESITY, FAT MASS, AGE AND YEARS POST-MENOPAUSE

1978 ◽  
Vol 9 (1) ◽  
pp. 59-66 ◽  
Author(s):  
A. VERMEULEN and ◽  
L. VERDONCK
Keyword(s):  
Fat Mass ◽  
Sex Hormone ◽  
Menopausal Women ◽  
Post Menopause ◽  
Post Menopausal

Sleep in post-menopausal women: Differences between early and late post-menopause

2009 ◽  
Vol 145 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Helena Hachul ◽  
Lia Rita Azeredo Bittencourt ◽  
José Maria Soares ◽  
Sergio Tufik ◽  
Edmund Chada Baracat
Keyword(s):  
Menopausal Women ◽  
Post Menopause ◽  
Post Menopausal

Non-weight-bearing effect of trunk and peripheral fat mass on bone mineral density in pre- and post-menopausal women

Maturitas ◽  
2008 ◽  
Vol 60 (3-4) ◽  
pp. 244-247 ◽  
Author(s):  
Akiko Kuwahata ◽  
Yukie Kawamura ◽  
Yukie Yonehara ◽  
Takashi Matsuo ◽  
Ichiro Iwamoto ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Fat Mass ◽  
Weight Bearing ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals Snoring is associated with body composition in （peri-post）menopausal women

2019 ◽  
Author(s):  
minfang tao ◽  
yang zhou ◽  
fei liu ◽  
changbin li ◽  
yanwei zheng ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Chinese Women ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Menopausal Transition ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Menopausal Women ◽  
Post Menopausal

Abstract Background: Little attention has been paid to whether snoring frequency is associated with body composition in menopausal women, particularly in China. This study objected to investigate the association between self-reported snoring and body composition in (peri-post) menopausal Chinese women as well as glucose/lipid metabolic indicators. Methods: This cross-sectional study enrolled 715 participants aged 40-67 years from the Menopause Clinic in the Shanghai Sixth People’s Hospital. Participants were categorized into four subgroups stratified by self-reported snoring frequency: never, rarely (<1 night per week), occasionally (1-2 nights per week), regularly (≥3 nights per week), while body composition was measured using bioelectrical impedance analysis(BIA).Besides, blood sample were collected to test the glycolipid indicators. Results: In our sample of investigation, regular snoring (≥3 nights per week) was found to be an independent risk factor for higher fat mass (total, upper limbs, trunk), with the highest risk of 2.4 times for fat mass of trunk after adjusting for glucose/lipid metabolic confounders(p=0.003). Meanwhile, regular snoring was independently associated with higher fat mass (total and each segment) only in the menopausal transition (p=0.023). Conclusion: We suggested that self-reported regular snoring may be taken as a simple alternative to predict higher fat mass (≥17.11kg, upper quartile) in menopausal women. Similarly, body composition should be attached to the great importance to those who in menopausal transition in order to help to prevent obstructive sleep apnea(OSA).

Abstract MP04: Sex Hormones and 10 Year Progression of Coronary Artery Calcium Among Post-Menopausal Women in the Multi-Ethnic Study of Atherosclerosis

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Vinita Subramanya ◽  
Di Zhao ◽  
Pamela Ouyang ◽  
Wendy Ying ◽  
Dhananjay Vaidya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Sex Hormones ◽  
Coronary Artery Calcium ◽  
Cardiac Ct ◽  
Sex Hormone ◽  
Cvd Risk ◽  
Menopausal Women ◽  
Androgenic Hormone ◽  
Post Menopausal

Background: Cardiovascular disease (CVD) is the leading cause of death in women. Sex differences in risk factors, prevalence and mortality suggest the involvement of sex hormones in disease processes. Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis and its progression. CAC is prognostic of CVD risk, independent of traditional risk factors, even among low-risk women. We hypothesized that a more androgenic hormone pattern will predict CAC progression over 10 years in post-menopausal women. Methods: We studied 2759 post-menopausal women, aged 45-84 years, participating in MESA who underwent serum sex hormone measurement and a cardiac CT scan for CAC at baseline (2000-2002). Among these, 2427 women had up to 3 follow-up cardiac CT scans at subsequent visits spanning 10 years. CAC was assessed by Agatson units. CAC and sex hormones were log-transformed for analysis. Using multivariable-adjusted Poisson and linear mixed effects models, we tested the longitudinal associations of testosterone (T), free T, dehydroepiandrosterone (DHEA), estradiol (E2), and sex hormone binding globulin (SHBG) with prevalent CAC and progression of CAC over 10 years. Results: At baseline, average age was 65 years, 46% had prevalent CAC and 32% were using hormone therapy (HT). Cross-sectionally, there were no associations between sex hormones and prevalent CAC. After adjustment for demographics, lifestyle factors and use of HT, higher levels of free T and lower levels of SHBG were associated with an increase in CAC progression over 10 years ( Table, Model 2). These associations remained statistically significant after adjusting for potential mediating cardiovascular risk factors (Model 3) and in sensitivity analyses excluding women on HT. Conclusion: A more androgenic hormone profile of higher free T and lower SHBG is associated with a greater CAC progression over 10 years in post-menopausal women. Sex hormone levels may help identify women at increased CVD risk who may benefit from other risk reduction strategies.

Abstract P012: Association Between Testosterone And Sex Hormone Binding Globulin And Risk Of Ischemic Stroke: The Atherosclerosis Risk In Communities Study

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Carin A Northuis ◽  
Erin Michos ◽  
Christie M Ballantyne ◽  
Ron C Hoogeveen ◽  
Pamela L Lutsey ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Sex Hormones ◽  
Stroke Risk ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Atherosclerosis Risk In Communities ◽  
Menopausal Women ◽  
Atherosclerosis Risk ◽  
Post Menopausal

Background: Sex hormones are associated with obesity, diabetes mellitus, and other stroke risk factors; however, studies on sex hormones and stroke risk report inconsistent results. We assessed the associations of testosterone and sex hormone binding globulin (SHBG) with risk of ischemic stroke among men and post-menopausal women in the Atherosclerosis Risk in Communities (ARIC) Study. Methods: A total of 4,349 men and 4,720 post-menopausal women who had SHBG and total testosterone measurements at visit 4 (1996-98) were followed through 2018 for the development of ischemic stroke. We examined log transformed SHBG and testosterone exposure as quartiles and as per 1 SD increment. We used Cox regression to estimate the hazard ratios (HR) for ischemic stroke, adjusting for demographic, behavioral and clinical variables. Analyses were stratified by sex and menopausal hormone therapy (HT) use. Results: Participants were aged 63±6 years at baseline, 52% were women (25% HT users), and 21% Black. There were 691 strokes over a median follow-up of 19.8 years. Mean log SHBG (nmol/L) and testosterone (nmol/L) were 4.3±0.7 and 3.1±0.5 for HT users, 3.6±0.7 and 3.2±0.5 for non-HT users, and 3.4±0.5 and 6.2±0.5 for men. Quartile 1 vs Q4 for SHBG and testosterone were ≤50.3 vs >121 and ≤16 vs >28 in HT users, ≤23.3 vs >55 and ≤17.9 vs >32.7 in non-HT users, and ≤23.3 vs >41.8 and ≤388 vs >657 in men. SHBG and testosterone were not significantly associated with stroke in any group (Figure). The HRs [95% confidence interval] for highest to lowest SHBG and testosterone quartiles were 1.04 [0.51-2.14] and 1.64 [0.85-3.17] in HT-users, 1.02 [0.70-1.48] and 1.16 [0.83-1.62] in HT non-users, and 0.96 [0.70-1.32] and 0.87 [0.63-1.21] in men, respectively. The HRs for stroke associated with 1 SD increase in SHBG and testosterone were 1.14 [0.88-1.46] and 1.19 [0.96-1.46] in HT users. Associations were also null among non-HT users and men. Conclusion: SHBG and testosterone were not associated with ischemic stroke risk in this cohort of older men and post-menopausal women.

scholarly journals Impact of a lignan-rich diet on adiposity and insulin sensitivity in post-menopausal women

2009 ◽  
Vol 102 (2) ◽  
pp. 195-200 ◽  
Author(s):  
Anne-Sophie Morisset ◽  
Simone Lemieux ◽  
Alain Veilleux ◽  
Jean Bergeron ◽  
S. John Weisnagel ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Body Fat ◽  
Fat Mass ◽  
Metabolic Profile ◽  
Body Fat Mass ◽  
Dietary Record ◽  
Menopausal Women ◽  
Total Body Fat ◽  
Total Body ◽  
Post Menopausal

There has been a growing interest in lignans, a class of phyto-oestrogens, because of their potentially favourable effects on human health. The aim of the present study was to compare the metabolic profile of post-menopausal women consuming various amounts of dietary lignans. Phyto-oestrogen intake was assessed using a 3-d dietary record analysed with a Canadian food phyto-oestrogen content data table in 115 post-menopausal women (age 56·8 (sd 4·4) years and BMI 28·5 (sd 5·9) kg/m2). Plasma enterolactone (ENL), the major biologically active metabolite of dietary lignans, was determined by time-resolved fluoroimmunoassay. Anthropometrics, abdominal adipose tissue areas (computed tomography), body composition (hydrostatic weighing) and insulin sensitivity (hyperinsulinaemic–euglycaemic clamp) were measured in all women. Women in the high dietary lignan intake subgroup (n 29) had a significantly lower BMI and total body fat mass, as well as a better glucose disposal rate (GDR; P < 0·05), compared with women in the low lignan intake subgroup (n 28). The majority of women with the highest dietary lignan intake were also in the highest quartile of plasma ENL (59 %). Women in the highest ENL quartile had a significantly lower BMI (26·1 (sd 4·4) v. 30·4 (sd 6·9) kg/m2, P < 0·05), total body fat mass (24·8 (sd 9·8) v. 33·3 (sd 13·3) kg, P < 0·05), 2 h postload glycaemia (5·5 (sd 0·9) v. 5·7 (sd 0·8) nmol/l, P < 0·05) and a higher GDR (8·3 (sd 2·7) v. 5·5 (sd 2·8), P < 0·01) compared with women in the lowest ENL quartile. In conclusion, women with the highest ENL concentrations had a better metabolic profile including higher insulin sensitivity and lower adiposity measures.

scholarly journals Phyto-oestrogens and bone health

2008 ◽  
Vol 67 (2) ◽  
pp. 184-195 ◽  
Author(s):  
Véronique Coxam
Keyword(s):  
Hormone Replacement Therapy ◽  
Bone Loss ◽  
Replacement Therapy ◽  
Bone Health ◽  
Hormone Replacement ◽  
Early Period ◽  
Long Duration ◽  
Menopausal Women ◽  
Post Menopause ◽  
Post Menopausal

As oestrogen deficiency is the main cause in the pathogenesis of osteoporosis hormone-replacement therapy remains the mainstay for prevention. However, prophylaxis by hormone-replacement therapy is limited. Phyto-oestrogens, which are weakly-oestrogenic compounds present in plants, deserve particular mention because emerging data support the suggestion that they may prevent bone loss associated with the menopause. In the past few years extensive research using animal models has provided convincing data to indicate a significant improvement in bone mass or other end points following feeding with soyabean. Moreover, observational studies relate the lower incidence of osteoporosis among women in the Eastern world to a diet rich in phyto-oestrogens. However, it is not valid to extrapolate to the Western situation. The varied clinical trials that have been published suggest that isoflavones reduce bone loss in women in the early period post menopause, but a definitive result requires more investigations of the effect of phyto-oestrogens on bone health that have substantial sample size and are of long duration. In addition, the clinical efficacy of soya foods in preventing osteopenia depends on their intestinal metabolism. Thus, phyto-oestrogens are a source for putative innovative dietary health intervention for post-menopausal women. However, more data are necessary, particularly in relation to their effect on the risk of fracture.

scholarly journals STUDY OF CALCIUM, PHOSPHORUS AND ACID PHOSPHATASE IN PRE-AND POST-MENOPAUSAL WOMEN

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Gangaram Bhadarge ◽  
Badade ZG ◽  
Rahul Kadam
Keyword(s):  
Acid Phosphatase ◽  
Phosphorus Acid ◽  
T Score ◽  
Menopausal Women ◽  
The World ◽  
Calcium Phosphorus ◽  
Post Menopause ◽  
Post Menopausal ◽  
One Year ◽  
Hazard Factor

Introduction: More than 75 million individuals overall experience the ill effects of osteoporosis of which 80 % for example 44 million are postmenopausal ladies. Osteoporosis is second just to cardiovascular disease as a main medicinal services issue, as per the World Health Organization. Around the world, the lifetime hazard for ladies to have an osteoporotic break is 30 – 40%. Menopauseis one of the most significant physiological occasions; it is identified with the suspension of ovarian capacity and the finish of conceptive cycle. The occurrence of osteoporosis in postmenopausal ladies keeps on expanding with continuously maturing populaces. Pre-menopause refers to a ladies' regenerative or rich life, from the main menstrual period to the last. Post-menopause is characterized as the time after menopause, in any event one year without a period. Osteoporosisis a dynamic infection which prompts the exhaustion in the bone structure with loss of bone mineral thickness (BMD) expanding the hazard factor of breaks throughout the years. High danger of creating osteoporosis is described by low BMD and shows a disintegration of the smaller scale engineering with the BMD is the consequence of a harmony between bone resorption because of osteoclasts and bone arrangement because of osteoblasts, during an on-going renovating process. Aim: Study of Calcium, Phosphorus, Acid Phosphatase and BMD T score in Pre-and Post-Menopausal Women. Material and Methods: The present study includes total 100 subjects that include 50 pre-menopausal women (age 35 to 45 years) and 50 post -menopause women (age 46 to 60 years).  Blood samples were collected from the subjects were obtained for Calcium, Phosphorus and Acid Phosphatase from Medicine /Orthopaedics/ Obstetrics and Gynaecology Wards. Conclusion: Menopause is one of the most significant physiological occasions: it is identified with the end of ovarian capacity and the finish of conceptive cycle. The rate of osteoporosis in postmenopausal ladies keeps on expanding with continuously maturing populaces. Pre-menopause alludes to a lady's regenerative or prolific life, from the principal menstrual period to the last. Post-menopause is the time after menopause, in any event one year without a period. Beginning stage of menopause builds hazard for some postmenopausal wellbeing inconveniences, for example, osteoporosis, ischemic ailment, and ovarian malignancy, though later menopause is a hazard factor for endometrial and bosom disease. Abbreviation: Menopause, Osteoporosis, BMD T score, Calcium, Phosphorus, Acid phosphatase.

Sign in / Sign up

Export Citation Format

Share Document