EFFECT OF HAEMORRHAGE ON THE POWER OF LOW FREQUENCY BLOOD PRESSURE FLUCTUATIONS IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS

1995 ◽  
Vol 22 (s1) ◽  
pp. S112-Sl13
Author(s):  
S. Eliash ◽  
O. Oz ◽  
S. Akselrod ◽  
S. Cohen
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Pressure Fluctuations ◽  
Low Frequency ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

scholarly journals Effects of Chronic Cholinergic Stimulation Associated With Aerobic Physical Training on Cardiac Morphofunctional and Autonomic Parameters in Spontaneously Hypertensive Rats

2021 ◽  
Author(s):  
Camila B. Gardim ◽  
Ana Catarine V. Oliveira ◽  
Bruno Augusto Aguilar ◽  
Stella V. Philbois ◽  
Hugo C. D. Souza
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Physical Training ◽  
Spontaneously Hypertensive Rats ◽  
Low Frequency ◽  
Pyridostigmine Bromide ◽  
Cholinergic Stimulation ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Pharmacological Blockade

Abstract We investigated in spontaneously hypertensive rats (SHR) the hemodynamic, cardiac morphofunctional, and cardiovascular autonomic adaptations after a protocol of aerobic physical training associated with chronic cholinergic stimulation. Fifty-four SRH were divided into two groups: trained and untrained. Afterward, each group was subdivided into three smaller groups: vehicle, treated with pyridostigmine bromide at 5mg/kg/day, and at 15mg/kg/day. The following protocols were assessed: echocardiography, autonomic double pharmacological blockade, analysis of heart rate variability (HRV), blood pressure variability (BPV), and baroreflex sensitivity (BRS). Physical training and pyridostigmine bromide reduced blood pressure and heart rate and increased vagal participation in cardiac tonic autonomic balance. Associated the responses were potentialized. Pyridostigmine bromide increased the oscillation of low frequency (LF:0.2-0.75Hz) and high frequency (HF:0.75-3Hz) of HRV. However, the association with physical training attenuated HF oscillations. Pyridostigmine bromide also increased LF oscillations of BPV. Both treatments promoted morphofunctional adaptations and associated increased the ejection volume, ejection fraction, cardiac output, and cardiac index. In conclusion, the association of pyridostigmine bromide and physical training promoted greater benefits in hemodynamic parameters and increase vagal influence on cardiac autonomic tonic balance. Nonetheless, pyridostigmine bromide alone seems to negatively affect BPV, while the association of treatment negatively influences HRV.

An experimental study in reducing blood pressure in spontaneously hypertensive rats through extracellular signal-regulated kinase inhibition

2010 ◽  
Vol 34 (8) ◽  
pp. S31-S31
Author(s):  
Li Jing ◽  
Jian‑zhong Zhang ◽  
Jin‑ping Sun ◽  
Xin An ◽  
Feng‑ying Guo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Experimental Study ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Kinase Inhibition ◽  
Spontaneously Hypertensive ◽  
Extracellular Signal Regulated Kinase ◽  
Extracellular Signal

INFLUENCE OF BRADYKININ ON BLOOD PRESSURE REGULATION OF SPONTANEOUSLY HYPERTENSIVE RATS MAINTAINED ON DIFFERENT SODIUM INTAKES

1987 ◽  
Vol 14 (8) ◽  
pp. 659-664 ◽  
Author(s):  
B. Waeber ◽  
J. F. Aubert ◽  
J. Nussberger ◽  
R. Vavrek ◽  
J. M. Stewart ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Blood Pressure Regulation ◽  
Pressure Regulation ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

Effect oftrans fatty acids on plasma lipids, platelet function and systolic blood pressure in stroke-prone spontaneously hypertensive rats

Lipids ◽  
1991 ◽  
Vol 26 (1) ◽  
pp. 46-52 ◽  
Author(s):  
M. T. Chiang ◽  
M. I. Otomo ◽  
H. Itoh ◽  
Y. Furukawa ◽  
S. Kimura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Fatty Acids ◽  
Systolic Blood Pressure ◽  
Platelet Function ◽  
Spontaneously Hypertensive Rats ◽  
Plasma Lipids ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive
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