ENDOSCOPIC OBSERVATION OF MUCOSAL SPREAD LESION OF CHOLANGIOCARCINOMA USING PERORAL CHOLANGIOSCOPY WITH NARROW BAND IMAGING

Abstract Background The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to elucidate the appropriate air volume during endoscopic observation to improve the visibility of esophageal SCC. Methods This retrospective study included a total of 101 flat type esophageal SCCs identified between April 2017 and January 2019 at the Department of Gastrointestinal Oncology, Osaka International Cancer Institute. Video images of narrow band imaging (NBI) under both less-air and standard-air conditions were recorded digitally. Videos were evaluated by five endoscopists. Relative visibility between less-air and standard-air conditions of the brownish area, brownish color change of the epithelium, and dilated intrapapillary capillary loop (IPCL) were graded as 5 (definitely better under less-air condition) to 1 (definitely worse under less-air condition), with 3 indicating average visibility (equivalent to standard-air observation). Results The mean (standard deviation) visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs under less-air condition were 3.94 (0.58), 3.73 (0.57), and 4.13 (0.60), respectively, which were significantly better than that under standard-air condition (p < 0.0001). Esophageal SCC evaluated as ≥ 4 in the mean visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs accounted for 50% (51/101 lesions), 34% (34/101 lesions), and 67% (68/101 lesions), respectively. Conclusions The present results suggested that NBI with less air might improve the visibility of flat type esophageal SCC compared with NBI with standard air. Less-air NBI observation may facilitate the detection of flat type esophageal SCC. Trial registration The present study is a non-intervention trial.

Download Full-text

369 Usefulness of Direct Peroral Cholangioscopy Using an Ultra-Slim Upper Endoscope Combined With Narrow-Band Imaging for the Diagnosis of Superficial Flat Elevated or Polypoid Lesions of Bile Duct

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2012.04.054 ◽

2012 ◽

Vol 75 (4) ◽

pp. AB137

Author(s):

Jong Ho Moon ◽

Hyun Jong Choi ◽

Su Jin Hong ◽

Bong MIN Ko ◽

Sang Gyune Kim ◽

...

Keyword(s):

Bile Duct ◽

Narrow Band ◽

Narrow Band Imaging ◽

Peroral Cholangioscopy ◽

Direct Peroral Cholangioscopy

Download Full-text

Magnifying Endoscopic Features of Follicular Lymphoma Involving the Stomach: A Report of Two Cases

Case Reports in Gastrointestinal Medicine ◽

10.1155/2016/2082698 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Masaya Iwamuro ◽

Katsuyoshi Takata ◽

Seiji Kawano ◽

Nobuharu Fujii ◽

Yoshiro Kawahara ◽

...

Keyword(s):

Lymph Nodes ◽

Follicular Lymphoma ◽

Narrow Band ◽

Narrow Band Imaging ◽

Gastric Body ◽

Mesenteric Lymph Nodes ◽

Mesenteric Lymph ◽

Endoscopic Observation ◽

Structural Differences ◽

Detection And Recognition

A 70-year-old woman presented with follicular lymphoma involving the stomach, duodenum, jejunum, bone, and lymph nodes. Esophagogastroduodenoscopy revealed multiple depressed lesions in the stomach. Examination with magnifying endoscopy showed branched abnormal vessels along with gastric pits, which were irregularly shaped but were preserved. The second case was a 45-year-old man diagnosed with stage II1follicular lymphoma with duodenal, ileal, and colorectal involvement, as well as lymphadenopathy of the mesenteric lymph nodes. Esophagogastroduodenoscopy performed six years after the diagnosis revealed multiple erosions in the gastric body and angle. Magnifying endoscopic observation with narrow-band imaging showed that the gastric pits were only partially preserved and were destroyed in most of the stomach. Branched abnormal vessels were also seen. Pathological features were consistent with follicular lymphoma in both cases. The structural differences reported between the two cases appear to reflect distinct pathologies. Disappearance of gastric pits in the latter case seems to result from loss of epithelial cells, probably due to chronic inflammation. In both cases, branched abnormal vasculature was observed. These two cases suggest that magnified observations of abnormal branched microvasculature may facilitate endoscopic detection and recognition of the extent of gastric involvement in patients with follicular lymphoma.

Download Full-text